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Upstream Bio, Inc. (UPB) stock

UPBNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 11, 2026Score 9/30
$3.41+0.14 (+4.28%)

Close on Oct 30, 2026Market cap $186.77MP/E –Yield –

Price history

Upstream Bio share prices for every trading day, newest first. Adjusted for stock splits, not for dividends.

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Close, Oct 30, 2026
$3.41
+4.28% on the day
52-week range
$2.68 – $33.68
-89.9% from the high
Change over 52 weeks
-86.8%
From $25.77 on Oct 30, 2025
Average volume
757,862
Shares a day, last 90 sessions
DateOpenHighLowCloseChangeVolume
Oct 30, 2026$3.26$3.43$3.15$3.41+4.28%946,124
Oct 29, 2026$3.00$3.32$2.97$3.27+9.73%1,179,150
Oct 28, 2026$2.78$2.99$2.68$2.98+6.81%1,323,093
Oct 27, 2026$2.76$2.94$2.68$2.79+1.45%1,179,621
Oct 26, 2026$2.75$2.97$2.72$2.75+0.36%983,844
Oct 23, 2026$2.95$2.96$2.70$2.74-8.36%1,051,217
Oct 22, 2026$2.77$2.99$2.70$2.99+6.79%1,450,028
Oct 21, 2026$2.83$2.98$2.77$2.80-0.71%1,410,488
Oct 20, 2026$2.79$3.09$2.78$2.82+0.71%1,676,022
Oct 19, 2026$2.76$3.07$2.75$2.80+1.45%1,603,699
Oct 16, 2026$3.39$3.39$2.74$2.76-18.10%1,836,415
Oct 15, 2026$3.44$3.56$3.29$3.37-1.46%1,285,463
Oct 14, 2026$3.48$3.60$3.29$3.42-3.66%1,574,473
Oct 13, 2026$4.14$4.16$3.52$3.55-14.87%1,037,523
Oct 12, 2026$4.68$4.72$4.12$4.17-11.28%848,408
Oct 9, 2026$4.54$4.76$4.51$4.70+3.30%1,187,830
Oct 8, 2026$4.53$4.65$4.37$4.55-1.30%2,857,189
Oct 7, 2026$4.55$4.72$4.50$4.61+0.44%908,403
Oct 6, 2026$4.84$4.87$4.53$4.59-5.36%1,062,306
Oct 5, 2026$5.07$5.10$4.67$4.85-3.77%1,010,578
Oct 2, 2026$5.12$5.21$4.86$5.040.00%956,519
Oct 1, 2026$5.25$5.35$4.98$5.04-4.36%832,377
Sep 30, 2026$5.23$5.46$5.15$5.27+1.54%851,221
Sep 29, 2026$5.28$5.31$4.99$5.19-2.08%784,211
Sep 28, 2026$5.34$5.39$5.12$5.30-1.12%615,402
Sep 25, 2026$5.20$5.39$5.07$5.36+3.68%429,212
Sep 24, 2026$5.19$5.20$5.05$5.17-0.39%566,581
Sep 23, 2026$5.48$5.49$4.99$5.19-5.46%552,994
Sep 22, 2026$5.44$5.56$5.38$5.49+2.33%360,533
Sep 21, 2026$5.42$5.44$5.27$5.37+0.47%364,035

Seasonality

UPB return in each calendar month over the last 3 years, including dividends. The current month runs to the latest close.

YearJanFebMarAprMayJunJulAugSepOctNovDec
Average-10.0%-50.8%-2.8%26.7%-4.6%0.9%15.3%8.4%-5.3%1.1%-0.6%-14.9%
Months up1 of 20 of 21 of 22 of 20 of 21 of 21 of 22 of 21 of 21 of 21 of 20 of 2
202614.5%-75.3%17.2%2.0%-8.9%-17.2%-8.8%4.9%-20.4%-35.3%
2025-34.5%-26.4%-22.8%51.3%-0.3%19.0%39.4%11.9%9.8%37.4%10.6%-5.1%
2024-11.8%-24.8%