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UPBNasdaqPharmaceutical PreparationsFiscal year ends December 31

Upstream Bio, Inc.

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 11, 2026
$2.80+0.04 (+1.45%)

Close on Oct 19, 2026

Market cap
$152.79M
P/E (TTM)
–
Dividend yield
–

Share price

−$18.17 (−86.65%)past year

Daily closes, adjusted for splits. Drag across the chart to measure a change.Earnings

Upstream Bio, Inc. grew revenue 16.0% to $3.16M over the twelve months to Jun 30, 2026. Free cash flow was -$133.44M.

Revenue
$3.16M
+16.0% vs. a year earlier
Operating income
-$169.98M
TTM Q2 2026
Free cash flow
-$133.44M
FY2025
EPS, diluted
-$2.89
TTM Q2 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Jun 30, 2026

Valuation

Market cap
$152.79M
P/E ratio
–
Price to sales
48.38
Price to book
0.56
Dividend yield
–
Free cash flow yield
-87.34%

Fundamentals

Revenue
$3.16M
Net income
-$156.50M
EPS, diluted
-$2.89
Free cash flow
-$133.44M
Book value per share
$4.97
Diluted shares
55M

Four years at a glance

Fiscal years 2022 to 2025 and trailing twelve months, USD

Revenue

$3.16M+16.0% YoY

Operating income

-$169.98M

Net income

-$156.50M

EPS, diluted

-$2.89

Free cash flow

–
Reported periodTrailing twelve months