StockData

Spyre Therapeutics, Inc. (SYRE) stock

SYRENasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 4, 2026Score 7/30
$96.56−2.40 (-2.43%)

Close on Oct 30, 2026Market cap $8.51BP/E –Yield –

Price history

Spyre Therapeutics share prices for every week, newest first. Adjusted for stock splits, not for dividends.

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Close, Oct 30, 2026
$96.56
-2.43% on the day
52-week range
$21.15 – $110.18
-12.4% from the high
Change over 52 weeks
+298.0%
From $24.26 on Oct 30, 2025
Average volume
1.25M
Shares a day, last 90 sessions
Week ofOpenHighLowCloseChangeVolume
Oct 26, 2026$91.54$100.42$90.35$96.56+6.90%3,535,423
Oct 19, 2026$82.29$95.17$80.94$90.33+13.05%5,439,699
Oct 12, 2026$86.30$86.62$76.87$79.90-6.76%6,361,130
Oct 5, 2026$93.02$95.01$77.05$85.69-8.05%11,057,653
Sep 28, 2026$84.72$95.27$83.26$93.19+8.75%7,092,531
Sep 21, 2026$91.07$94.06$82.93$85.69-5.05%5,880,624
Sep 14, 2026$90.21$95.19$88.47$90.25-0.39%8,013,280
Sep 8, 2026$85.00$92.10$85.00$90.60+1.82%4,043,965
Aug 31, 2026$89.15$90.97$84.00$88.98-1.53%6,562,034
Aug 24, 2026$106.49$110.15$89.45$90.36-15.15%7,111,477
Aug 17, 2026$102.94$110.18$101.44$106.49+2.76%4,722,873
Aug 10, 2026$106.19$107.00$95.61$103.63-1.22%3,749,020
Aug 3, 2026$97.15$108.14$92.71$104.91+6.69%3,748,968
Jul 27, 2026$102.01$105.05$92.37$98.33-3.72%4,872,727
Jul 20, 2026$101.02$103.57$97.00$102.13+1.90%3,570,792
Jul 13, 2026$95.72$105.09$92.37$100.23+2.55%7,798,001
Jul 6, 2026$87.27$99.34$86.60$97.74+12.82%6,044,325
Jun 29, 2026$86.56$91.96$84.81$86.63-1.43%6,138,520
Jun 22, 2026$95.00$102.06$81.65$87.89-0.51%16,040,794
Jun 15, 2026$81.57$90.99$80.79$88.34+9.35%6,451,167
Jun 8, 2026$75.53$84.43$70.89$80.79+9.69%5,837,487
Jun 1, 2026$72.39$79.54$68.50$73.65+0.20%6,015,187
May 26, 2026$74.87$76.12$71.08$73.50-0.74%2,579,648
May 18, 2026$75.08$75.65$64.67$74.05-1.16%4,867,060
May 11, 2026$75.15$78.80$72.54$74.92-0.17%6,279,078
May 4, 2026$68.26$75.91$67.18$75.05+8.10%5,495,948
Apr 27, 2026$69.53$76.00$67.50$69.42-0.36%6,074,114
Apr 20, 2026$72.20$74.84$68.33$69.67-4.57%4,636,111
Apr 13, 2026$67.00$75.00$59.02$73.01+42.35%15,552,365
Apr 6, 2026$47.58$54.39$46.79$51.29+7.80%3,722,501
Mar 30, 2026$47.75$51.06$44.80$47.58+0.57%3,085,126
Mar 23, 2026$42.02$49.31$40.91$47.31+14.69%4,336,851
Mar 16, 2026$40.73$45.39$40.73$41.25+3.41%4,927,681
Mar 9, 2026$39.75$42.93$39.00$39.89-0.65%3,668,781
Mar 2, 2026$41.27$42.93$38.36$40.15-6.65%3,595,483
Feb 23, 2026$43.01$45.76$42.03$43.01-0.46%3,484,127
Feb 17, 2026$36.39$43.56$34.96$43.21+17.96%4,465,923
Feb 9, 2026$35.12$37.98$32.35$36.63+4.30%3,633,533
Feb 2, 2026$31.76$35.21$30.92$35.12+9.82%3,068,895
Jan 26, 2026$31.52$34.03$31.52$31.98-0.17%2,196,194
Jan 20, 2026$32.34$35.07$31.62$32.04-3.63%2,364,581
Jan 12, 2026$30.60$34.21$30.00$33.24+8.59%3,527,606
Jan 5, 2026$30.49$31.69$28.00$30.61+0.10%3,354,062
Dec 29, 2025$32.77$33.31$30.11$30.58-7.16%2,163,267
Dec 22, 2025$32.93$34.52$32.30$32.94-1.38%2,299,360
Dec 15, 2025$33.93$34.96$32.26$33.40-0.65%6,394,926
Dec 8, 2025$33.95$35.31$33.24$33.62+0.51%4,467,025
Dec 1, 2025$30.55$34.54$28.16$33.45+11.50%4,316,882
Nov 24, 2025$24.95$30.21$24.58$30.00+23.66%2,658,981
Nov 17, 2025$23.47$25.42$23.01$24.26+3.23%2,928,717
Nov 10, 2025$22.93$24.50$21.63$23.50+4.35%2,620,029
Nov 3, 2025$23.95$24.45$21.15$22.52-7.93%3,629,191

Seasonality

SYRE return in each calendar month over the last 10 years, including dividends. The current month runs to the latest close.

YearJanFebMarAprMayJunJulAugSepOctNovDec
Average3.5%2.9%2.2%-1.0%-4.6%17.5%1.0%8.2%0.3%13.4%1.0%-0.4%
Months up4 of 105 of 105 of 102 of 105 of 105 of 105 of 107 of 105 of 105 of 104 of 94 of 9
2026-2.4%34.5%17.3%47.6%-1.3%20.8%10.8%-9.2%-0.3%8.5%
2025-1.2%-14.3%-18.1%-5.6%0.3%-2.0%13.4%-2.8%1.6%45.9%22.6%9.2%
202420.4%5.9%38.2%-12.9%5.8%-32.7%17.0%4.5%2.3%10.6%-12.6%-18.1%
202311.1%-21.6%-26.0%-41.8%-23.0%246.8%25.4%1.8%-14.8%-5.0%60.3%15.3%
2022-9.5%-35.6%-17.0%-37.4%9.7%-68.0%-17.8%25.9%0.6%95.8%-59.7%8.4%
2021-11.7%7.2%6.3%-1.8%-15.0%5.3%-11.9%18.3%9.7%-7.9%-14.8%-23.9%
2020-5.0%-5.9%-31.8%66.7%13.4%5.0%-25.9%6.2%-2.5%8.3%11.5%-8.1%
201922.0%-8.5%-3.7%-14.9%-8.9%9.8%30.8%-12.9%-1.5%-1.0%12.4%-10.6%
201819.8%11.9%36.8%-5.8%14.3%-0.9%-20.5%30.0%-12.4%-9.8%-2.4%-11.0%
2017-8.3%55.4%20.2%-4.0%-41.0%-8.8%-11.4%20.5%19.9%-11.1%-8.7%35.3%