StockData

Spyre Therapeutics, Inc. (SYRE) stock

SYRENasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 4, 2026Score 7/30
$96.56−2.40 (-2.43%)

Close on Oct 30, 2026Market cap $8.51BP/E –Yield –

Price history

Spyre Therapeutics share prices for every trading day, newest first. Adjusted for stock splits, not for dividends.

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Close, Oct 30, 2026
$96.56
-2.43% on the day
52-week range
$21.15 – $110.18
-12.4% from the high
Change over 52 weeks
+298.0%
From $24.26 on Oct 30, 2025
Average volume
1.25M
Shares a day, last 90 sessions
DateOpenHighLowCloseChangeVolume
Oct 30, 2026$96.78$98.96$94.68$96.56-2.43%661,126
Oct 29, 2026$99.71$100.42$97.95$98.96-0.79%567,636
Oct 28, 2026$98.39$100.14$97.55$99.75+0.71%724,549
Oct 27, 2026$93.00$99.24$92.37$99.05+6.60%944,931
Oct 26, 2026$91.54$94.19$90.35$92.91+2.86%637,181
Oct 23, 2026$90.71$91.90$88.69$90.33-2.17%503,013
Oct 22, 2026$92.95$94.57$91.27$92.33-0.67%802,950
Oct 21, 2026$92.78$95.17$92.32$92.95+1.70%1,153,116
Oct 20, 2026$85.12$93.22$85.08$91.40+7.88%1,708,557
Oct 19, 2026$82.29$86.05$80.94$84.72+6.03%1,272,063
Oct 16, 2026$80.21$80.52$78.13$79.90-0.25%1,273,467
Oct 15, 2026$76.87$80.88$76.87$80.10+1.87%1,148,032
Oct 14, 2026$80.13$82.45$77.95$78.63-2.26%1,624,638
Oct 13, 2026$85.12$85.32$80.45$80.45-6.34%1,441,084
Oct 12, 2026$86.30$86.62$84.21$85.90+0.25%873,909
Oct 9, 2026$79.90$86.22$78.73$85.69+7.25%1,116,437
Oct 8, 2026$79.58$80.91$77.05$79.90-1.18%2,326,678
Oct 7, 2026$78.91$82.22$78.00$80.85+0.92%2,719,344
Oct 6, 2026$92.08$92.08$79.36$80.11-13.60%4,252,337
Oct 5, 2026$93.02$95.01$89.49$92.72-0.50%642,857
Oct 2, 2026$91.16$95.27$90.48$93.19+3.63%1,235,019
Oct 1, 2026$89.13$94.06$87.25$89.93+1.01%1,662,580
Sep 30, 2026$88.64$95.08$88.00$89.03+5.09%2,096,144
Sep 29, 2026$85.09$86.64$83.26$84.72-1.25%1,053,253
Sep 28, 2026$84.72$87.12$84.00$85.79+0.12%1,045,535
Sep 25, 2026$88.10$88.10$85.63$85.69-1.61%560,081
Sep 24, 2026$87.46$87.46$82.93$87.09-1.22%1,729,587
Sep 23, 2026$91.56$91.56$86.30$88.17-4.13%918,769
Sep 22, 2026$91.53$93.58$89.90$91.97-0.07%1,223,437
Sep 21, 2026$91.07$94.06$89.65$92.03+1.97%1,448,750

Seasonality

SYRE return in each calendar month over the last 10 years, including dividends. The current month runs to the latest close.

YearJanFebMarAprMayJunJulAugSepOctNovDec
Average3.5%2.9%2.2%-1.0%-4.6%17.5%1.0%8.2%0.3%13.4%1.0%-0.4%
Months up4 of 105 of 105 of 102 of 105 of 105 of 105 of 107 of 105 of 105 of 104 of 94 of 9
2026-2.4%34.5%17.3%47.6%-1.3%20.8%10.8%-9.2%-0.3%8.5%
2025-1.2%-14.3%-18.1%-5.6%0.3%-2.0%13.4%-2.8%1.6%45.9%22.6%9.2%
202420.4%5.9%38.2%-12.9%5.8%-32.7%17.0%4.5%2.3%10.6%-12.6%-18.1%
202311.1%-21.6%-26.0%-41.8%-23.0%246.8%25.4%1.8%-14.8%-5.0%60.3%15.3%
2022-9.5%-35.6%-17.0%-37.4%9.7%-68.0%-17.8%25.9%0.6%95.8%-59.7%8.4%
2021-11.7%7.2%6.3%-1.8%-15.0%5.3%-11.9%18.3%9.7%-7.9%-14.8%-23.9%
2020-5.0%-5.9%-31.8%66.7%13.4%5.0%-25.9%6.2%-2.5%8.3%11.5%-8.1%
201922.0%-8.5%-3.7%-14.9%-8.9%9.8%30.8%-12.9%-1.5%-1.0%12.4%-10.6%
201819.8%11.9%36.8%-5.8%14.3%-0.9%-20.5%30.0%-12.4%-9.8%-2.4%-11.0%
2017-8.3%55.4%20.2%-4.0%-41.0%-8.8%-11.4%20.5%19.9%-11.1%-8.7%35.3%