Pyxis Oncology, Inc. (PYXS) stock
PYXSNasdaqPharmaceutical PreparationsFiscal year ends December 31
$1.81−0.08 (-4.23%)
Close on Oct 30, 2026Market cap $150.97MP/E –Yield –
Price history
Pyxis Oncology share prices for every month, newest first. Adjusted for stock splits, not for dividends.
Close, Oct 30, 2026
$1.81
-4.23% on the day
52-week range
$1.03 – $5.55
-67.4% from the high
Change over 52 weeks
-47.1%
From $3.42 on Oct 30, 2025
Average volume
1.30M
Shares a day, last 90 sessions
| Month | Open | High | Low | Close | Change | Volume |
|---|---|---|---|---|---|---|
| Oct 2026 | $2.31 | $2.31 | $1.63 | $1.81 | -22.32% | 22,707,495 |
| Sep 2026 | $3.24 | $4.15 | $2.12 | $2.33 | -28.09% | 26,718,232 |
| Aug 2026 | $2.70 | $4.00 | $1.90 | $3.24 | +22.26% | 28,710,082 |
| Jul 2026 | $3.01 | $3.20 | $2.13 | $2.65 | -11.96% | 22,667,028 |
| Jun 2026 | $1.78 | $3.40 | $1.54 | $3.01 | +67.22% | 23,573,535 |
| May 2026 | $1.71 | $2.92 | $1.57 | $1.80 | +5.88% | 15,009,234 |
| Apr 2026 | $1.45 | $1.98 | $1.40 | $1.70 | +16.44% | 8,059,924 |
| Mar 2026 | $1.40 | $1.70 | $1.26 | $1.46 | -0.68% | 7,625,733 |
| Feb 2026 | $1.44 | $1.69 | $1.27 | $1.47 | +1.38% | 9,103,759 |
| Jan 2026 | $1.18 | $2.17 | $1.13 | $1.45 | +26.09% | 25,546,980 |
| Dec 2025 | $5.10 | $5.13 | $1.03 | $1.15 | -77.84% | 39,357,179 |
| Nov 2025 | $3.48 | $5.55 | $3.48 | $5.19 | +45.79% | 14,949,683 |
| Oct 2025 | $2.20 | $3.89 | $2.10 | $3.56 | +60.36% | 18,876,084 |
| Sep 2025 | $1.28 | $2.37 | $1.27 | $2.22 | +73.44% | 18,132,988 |
| Aug 2025 | $1.10 | $1.44 | $0.97 | $1.28 | +14.29% | 9,460,566 |
| Jul 2025 | $1.10 | $1.38 | $1.04 | $1.12 | +1.82% | 9,200,585 |
| Jun 2025 | $1.23 | $1.41 | $1.10 | $1.10 | -9.09% | 14,685,622 |
| May 2025 | $1.12 | $1.33 | $1.03 | $1.21 | +10.00% | 9,762,199 |
| Apr 2025 | $0.9799 | $1.16 | $0.8332 | $1.10 | +12.26% | 11,019,947 |
| Mar 2025 | $1.21 | $1.24 | $0.9799 | $0.9799 | -17.66% | 10,209,494 |
| Feb 2025 | $1.51 | $1.56 | $1.11 | $1.19 | -24.20% | 14,432,283 |
| Jan 2025 | $1.58 | $1.82 | $1.39 | $1.57 | +0.64% | 11,667,678 |
| Dec 2024 | $2.01 | $2.09 | $1.49 | $1.56 | -22.39% | 24,514,482 |
| Nov 2024 | $3.60 | $5.39 | $1.76 | $2.01 | -43.54% | 43,528,780 |
| Oct 2024 | $3.64 | $4.19 | $3.00 | $3.56 | -3.00% | 12,755,510 |
| Sep 2024 | $3.72 | $3.89 | $3.39 | $3.67 | -3.17% | 9,733,723 |
| Aug 2024 | $3.92 | $3.95 | $3.10 | $3.79 | -3.32% | 8,930,895 |
| Jul 2024 | $3.28 | $4.13 | $2.81 | $3.92 | +18.43% | 13,048,182 |
| Jun 2024 | $3.82 | $4.10 | $2.95 | $3.31 | -11.50% | 15,625,526 |
| May 2024 | $4.44 | $4.78 | $3.57 | $3.74 | -15.96% | 8,485,026 |
| Apr 2024 | $4.34 | $6.18 | $4.06 | $4.45 | +4.46% | 13,766,498 |
| Mar 2024 | $6.46 | $6.79 | $3.60 | $4.26 | -33.02% | 15,257,096 |
| Feb 2024 | $3.80 | $6.85 | $3.16 | $6.36 | +66.93% | 18,669,767 |
| Jan 2024 | $1.79 | $4.35 | $1.79 | $3.81 | +111.67% | 16,247,594 |
| Dec 2023 | $1.59 | $2.18 | $1.58 | $1.80 | +13.21% | 4,139,608 |
| Nov 2023 | $1.66 | $1.85 | $1.35 | $1.59 | -4.79% | 2,277,567 |
| Oct 2023 | $1.96 | $2.13 | $1.55 | $1.67 | -16.08% | 1,877,112 |
| Sep 2023 | $2.19 | $2.46 | $1.54 | $1.99 | -8.72% | 3,774,159 |
| Aug 2023 | $2.54 | $2.67 | $2.09 | $2.18 | -15.50% | 3,569,940 |
| Jul 2023 | $2.57 | $2.87 | $2.30 | $2.58 | +0.78% | 4,988,634 |
| Jun 2023 | $3.23 | $3.40 | $2.39 | $2.56 | -20.50% | 7,580,475 |
| May 2023 | $2.95 | $3.98 | $2.72 | $3.22 | +9.15% | 12,564,245 |
| Apr 2023 | $4.50 | $4.73 | $2.67 | $2.95 | -26.43% | 36,417,075 |
| Mar 2023 | $2.23 | $6.92 | $1.70 | $4.01 | +76.65% | 194,796,095 |
| Feb 2023 | $1.60 | $2.46 | $1.48 | $2.27 | +45.51% | 3,188,899 |
| Jan 2023 | $1.35 | $1.65 | $1.34 | $1.56 | +16.42% | 754,061 |
| Dec 2022 | $1.57 | $1.62 | $1.10 | $1.34 | -7.59% | 6,740,447 |
| Nov 2022 | $1.90 | $1.90 | $1.34 | $1.45 | -22.46% | 2,611,592 |
| Oct 2022 | $1.97 | $2.39 | $1.49 | $1.87 | -5.08% | 1,503,210 |
| Sep 2022 | $2.52 | $2.96 | $1.71 | $1.97 | -23.94% | 1,059,541 |
| Aug 2022 | $2.60 | $3.11 | $2.50 | $2.59 | -2.26% | 650,745 |
| Jul 2022 | $2.38 | $3.21 | $2.37 | $2.65 | +11.34% | 2,608,578 |
| Jun 2022 | $2.48 | $2.55 | $2.14 | $2.38 | -3.64% | 5,857,541 |
| May 2022 | $2.46 | $2.68 | $1.96 | $2.47 | +0.82% | 5,691,153 |
| Apr 2022 | $4.02 | $5.00 | $2.40 | $2.45 | -39.36% | 3,704,328 |
| Mar 2022 | $6.13 | $6.56 | $4.00 | $4.04 | -33.55% | 1,800,653 |
| Feb 2022 | $9.54 | $9.87 | $5.26 | $6.08 | -36.27% | 853,108 |
| Jan 2022 | $11.19 | $11.50 | $8.01 | $9.54 | -13.04% | 2,094,160 |
| Dec 2021 | $12.94 | $12.94 | $7.90 | $10.97 | -14.10% | 5,382,379 |
| Nov 2021 | $13.22 | $14.00 | $10.25 | $12.77 | -4.27% | 2,678,648 |
| Oct 2021 | $19.00 | $19.00 | $10.89 | $13.34 | – | 9,005,037 |
Seasonality
PYXS return in each calendar month over the last 6 years, including dividends. The current month runs to the latest close.
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Average | 28.4% | 10.7% | -1.7% | -6.5% | 2.0% | 4.5% | 4.1% | 3.1% | 1.9% | 2.8% | -5.9% | -21.7% |
| Months up | 4 of 5 | 3 of 5 | 1 of 5 | 3 of 5 | 4 of 5 | 1 of 5 | 4 of 5 | 2 of 5 | 1 of 5 | 1 of 5 | 1 of 5 | 1 of 5 |
| 2026 | 26.1% | 1.4% | -0.7% | 16.4% | 5.9% | 67.2% | -12.0% | 22.3% | -28.1% | -22.3% | ||
| 2025 | 0.6% | -24.2% | -17.7% | 12.3% | 10.0% | -9.1% | 1.8% | 14.3% | 73.4% | 60.4% | 45.8% | -77.8% |
| 2024 | 111.7% | 66.9% | -33.0% | 4.5% | -16.0% | -11.5% | 18.4% | -3.3% | -3.2% | -3.0% | -43.5% | -22.4% |
| 2023 | 16.4% | 45.5% | 76.7% | -26.4% | 9.2% | -20.5% | 0.8% | -15.5% | -8.7% | -16.1% | -4.8% | 13.2% |
| 2022 | -13.0% | -36.3% | -33.6% | -39.4% | 0.8% | -3.6% | 11.3% | -2.3% | -23.9% | -5.1% | -22.5% | -7.6% |
| 2021 | -4.3% | -14.1% |