TWSTNasdaqBiological Products, (No Diagnostic Substances)Fiscal year ends September 30
Twist Bioscience Corp
Financials through Q3 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 3, 2026
$139.77+7.02 (+5.29%)
Close on Oct 19, 2026
- Market cap
- $8.72B
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
100.0%
76M of 63M shares
Institutional holders
336
90 new, 31 sold out
Net institutional buying
-1M
In Q2 2026
Insider trades, 12 months
0 buys · 170 sales
Net sold $128.70M
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| FMR LLC | 8,760,081 | 13.20% | 13G (passive) amendment | Aug 31, 2026 |
| Artisan Investments GP LLC | 6,410,900 | 10.60% | 13G (passive) amendment | Sep 30, 2025 |
| Artisan Partners Limited Partnership | 6,217,213 | 10.10% | 13G (passive) amendment | Feb 27, 2026 |
| BlackRock, Inc. | 4,927,750 | 8.30% | 13G (passive) amendment | Mar 31, 2025 |
| Artisan Partners Holdings LP | 4,802,017 | 7.70% | 13G (passive) amendment | Jun 30, 2026 |
| Abigail P. Johnson | 4,703,044 | 7.60% | 13G (passive) | Jun 30, 2026 |
| ARK Investment Management LLC | 4,549,803 | 7.31% | 13G (passive) amendment | Jun 30, 2026 |
| T. Rowe Price Associates, Inc. | 3,634,470 | 5.80% | 13G (passive) | Jun 30, 2026 |
| Catherine D. Wood | 3,385,850 | 5.11% | 13G (passive) amendment | Aug 31, 2026 |
| Vanguard Capital Management | 3,101,909 | 5.05% | 13G (passive) | Mar 31, 2026 |
| State Street Corporation | 3,089,063 | 5.10% | 13G (passive) | Sep 30, 2025 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of TWST | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| BlackRock, Inc. | 5,833,891 | 9.30% | $600.19M | +279,529 | 0.01% |
| Artisan Partners Limited Partnership | 4,802,017 | 7.66% | $494.03M | −1,565,760 | 0.78% |
| FMR LLC | 4,703,044 | 7.50% | $483.85M | +2,813,099 | 0.02% |
| ARK Investment Management LLC | 4,549,803 | 7.26% | $468.08M | −1,792,930 | 3.04% |
| Price T Rowe Associates Inc /Md/ | 3,634,652 | 5.80% | $373.93K | +3,564,347 | 0.04% |
| State Street Corp | 3,232,532 | 5.15% | $332.56M | −438,150 | 0.01% |
| Vanguard Portfolio Management LLC | 2,824,989 | 4.51% | $290.63M | +175,888 | 0.01% |
| Vanguard Capital Management LLC | 2,699,280 | 4.30% | $277.70M | +60,236 | 0.01% |
| EdgePoint Investment Group Inc. | 2,521,635 | 4.02% | $259.43M | −2,860,886 | 1.96% |
| William Blair Investment Management, LLC | 2,174,594 | 3.47% | $223.72M | −3,095,124 | 0.67% |
| Farallon Capital Management LLC | 2,136,400 | 3.41% | $219.79M | +708,750 | 1.01% |
| Invesco Ltd. | 1,928,229 | 3.07% | $198.38M | −243,669 | 0.02% |
| Geode Capital Management, LLC | 1,619,361 | 2.58% | $166.63M | +99,648 | 0.01% |
| Thrivent Financial for Lutherans | 1,433,503 | 2.29% | $147.48K | +120,959 | 0.25% |
| Goldman Sachs Group Inc | 1,408,418 | 2.25% | $144.90M | −297,128 | 0.01% |
| Morgan Stanley | 1,189,861 | 1.90% | $122.41M | +643,016 | 0.01% |
| D. E. Shaw & Co., Inc. | 1,185,605 | 1.89% | $121.98M | +1,138,961 | 0.06% |
| Baillie Gifford & Co | 1,086,779 | 1.73% | $111.81M | −128,372 | 0.10% |
| Driehaus Capital Management LLC | 1,022,526 | 1.63% | $105.20M | +437,830 | 0.61% |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,000,344 | 1.60% | $102.92M | −495,755 | 0.06% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 336 | 76M | 100.0% | 90 / 100 | 101 / 31 | 19M | 20M |
| Q1 2026 | 281 | 77M | 100.0% | 70 / 76 | 89 / 27 | 18M | 10M |
| Q4 2025 | 244 | 75M | 100.0% | 48 / 75 | 77 / 38 | 9M | 9M |
| Q3 2025 | 239 | 75M | 100.0% | 34 / 98 | 63 / 35 | 11M | 8M |
| Q2 2025 | 244 | 71M | 100.0% | 35 / 80 | 89 / 51 | 9M | 8M |
| Q1 2025 | 263 | 70M | 100.0% | 47 / 91 | 79 / 26 | 9M | 5M |
| Q4 2024 | 247 | 66M | 100.0% | 32 / 89 | 84 / 28 | 6M | 8M |
| Q3 2024 | 246 | 69M | 100.0% | 35 / 91 | 77 / 50 | 12M | 7M |
| Q2 2024 | 263 | 69M | 100.0% | 62 / 88 | 79 / 35 | 10M | 12M |
| Q1 2024 | 238 | 73M | 100.0% | 44 / 79 | 75 / 24 | 6M | 6M |
| Q4 2023 | 219 | 73M | 100.0% | 46 / 57 | 74 / 20 | 13M | 6M |
| Q3 2023 | 195 | 66M | 100.0% | 28 / 57 | 66 / 26 | 5M | 7M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of TWST | Value | % of fund | As of |
|---|---|---|---|---|---|
| ARK Innovation ETF | 2,010,667 | 3.21% | $184.08M | 3.31% | Jul 31, 2026 |
| Vanguard Total Stock Market Index Fund | 1,874,473 | 2.99% | $192.85M | 0.01% | Jun 30, 2026 |
| iShares Russell 2000 ETF | 1,594,038 | 2.54% | $163.99M | 0.20% | Jun 30, 2026 |
| State Street(R) SPDR(R) S&P(R) Biotech ETF | 1,469,111 | 2.34% | $151.14M | 1.41% | Jun 30, 2026 |
| Vanguard Small-Cap Index Fund | 1,357,205 | 2.16% | $139.63M | 0.07% | Jun 30, 2026 |
| ARK Genomic Revolution ETF | 1,314,736 | 2.10% | $120.36M | 7.73% | Jul 31, 2026 |
| T. Rowe Price New Horizons Fund, Inc. | 959,300 | 1.53% | $98.69M | 0.67% | Jun 30, 2026 |
| Artisan Mid Cap Fund | 893,167 | 1.42% | $91.89M | 2.88% | Jun 30, 2026 |
| Bridge Builder Small/Mid Cap Growth Fund | 866,923 | 1.38% | $89.19M | 0.80% | Jun 30, 2026 |
| Invesco Discovery Fund | 822,247 | 1.31% | $54.98M | 0.70% | May 31, 2026 |
| Vanguard Small-Cap Growth Index Fund | 780,792 | 1.25% | $80.33M | 0.17% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 714,822 | 1.14% | $73.54M | 0.08% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund | 679,049 | 1.08% | $62.17M | 0.18% | Jul 31, 2026 |
| Vanguard Explorer Fund | 604,500 | 0.96% | $55.34M | 0.25% | Jul 31, 2026 |
| iShares Russell 2000 Growth ETF | 573,272 | 0.91% | $58.98M | 0.38% | Jun 30, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| Emily M. Leproust | Chief Executive Officer, Director | 616,205 | 0.98% | Sep 25, 2026 |
| Dennis Cho | See Remarks | 73,303 | 0.12% | Sep 23, 2026 |
| Paula Green | SVP of Human Resources | 116,720 | 0.19% | Sep 23, 2026 |
| Robert F. Werner | Chief Accounting Officer | 44,399 | 0.07% | Sep 10, 2026 |
| Patrick John Finn | President and COO | 210,802 | 0.34% | Aug 25, 2026 |
| Adam Laponis | Chief Financial Officer | 108,633 | 0.17% | Aug 25, 2026 |
| Katryn Blake | Director | 17,208 | 0.03% | Aug 14, 2026 |
| Robert Chess | Director | 63,612 | 0.10% | Aug 11, 2026 |
| Melissa A. Starovasnik | Director | 22,222 | 0.04% | Jun 1, 2026 |
| Jan Johannessen | Director | 29,754 | 0.05% | May 14, 2026 |
| Robert P. Ragusa | Director | 28,983 | 0.05% | Feb 9, 2026 |
| Keith Crandell | Director | 103,618 | 0.17% | Feb 9, 2026 |
| Nelson Chan | Director | 33,251 | 0.05% | Feb 9, 2026 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −83 | $184.60 | $15.32K | 613,699 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −2,485 | $175.23 | $435.45K | 616,417 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −945 | $176.39 | $166.69K | 615,472 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −164 | $177.17 | $29.06K | 615,308 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −330 | $178.67 | $58.96K | 614,978 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −143 | $179.93 | $25.73K | 614,835 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −515 | $180.39 | $92.90K | 614,320 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −21 | $181.45 | $3.81K | 614,299 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −501 | $183.76 | $92.06K | 613,782 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 24, 2026 | Sale(10b5-1 plan) | −16 | $182.50 | $2.92K | 614,283 |
| Paula Green SVP of Human Resources | Sep 21, 2026 | Sale | −294 | $165.49 | $48.65K | 116,720 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 21, 2026 | Sale | −1,687 | $165.49 | $279.18K | 618,902 |
| Dennis Cho See Remarks | Sep 21, 2026 | Sale | −348 | $165.49 | $57.59K | 73,303 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −14,493 | $160.44 | $2.33M | 635,192 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −23,884 | $159.53 | $3.81M | 649,685 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −232,173 | $158.09 | $36.70M | 673,569 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −32,260 | $157.49 | $5.08M | 905,742 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −9,097 | $156.47 | $1.42M | 938,002 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −13,378 | $155.46 | $2.08M | 947,099 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −869 | $163.39 | $141.99K | 620,589 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −3,399 | $153.40 | $521.41K | 964,652 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −6,644 | $152.21 | $1.01M | 968,051 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −2,440 | $151.46 | $369.56K | 974,695 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Option exercise | +75,439 | $8.82 | $665.37K | 977,135 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Option exercise | +133,269 | $26.66 | $3.55M | 901,696 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −11,169 | $161.49 | $1.80M | 624,023 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −2,565 | $162.31 | $416.33K | 621,458 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 17, 2026 | Sale(10b5-1 plan) | −4,175 | $154.17 | $643.66K | 960,477 |
| Paula Green SVP of Human Resources | Sep 8, 2026 | Sale | −907 | $122.62 | $111.22K | 117,014 |
| Robert F. Werner Chief Accounting Officer | Sep 8, 2026 | Sale | −238 | $122.62 | $29.18K | 44,399 |
| Dennis Cho See Remarks | Sep 8, 2026 | Sale | −412 | $122.62 | $50.52K | 73,651 |
| Emily M. Leproust Chief Executive Officer, Director | Sep 8, 2026 | Sale | −2,302 | $122.62 | $282.27K | 768,427 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 25, 2026 | Sale(10b5-1 plan) | −1,093 | $154.45 | $168.81K | 770,729 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 25, 2026 | Sale(10b5-1 plan) | −12,648 | $150.56 | $1.90M | 799,651 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 25, 2026 | Sale(10b5-1 plan) | −12,236 | $151.36 | $1.85M | 787,415 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 25, 2026 | Sale(10b5-1 plan) | −6,412 | $152.75 | $979.43K | 781,003 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 25, 2026 | Sale(10b5-1 plan) | −9,181 | $153.93 | $1.41M | 771,822 |
| Robert F. Werner Chief Accounting Officer | Aug 24, 2026 | Sale | −854 | $140.77 | $120.22K | 44,637 |
| Robert F. Werner Chief Accounting Officer | Aug 21, 2026 | Sale | −669 | $139.07 | $93.04K | 45,491 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 21, 2026 | Sale | −6,639 | $139.07 | $923.29K | 812,299 |
| Dennis Cho See Remarks | Aug 21, 2026 | Sale | −1,598 | $139.07 | $222.23K | 74,063 |
| Adam Laponis Chief Financial Officer | Aug 21, 2026 | Sale | −1,965 | $139.07 | $273.27K | 108,633 |
| Patrick John Finn President and COO | Aug 21, 2026 | Sale | −4,046 | $139.07 | $562.68K | 210,802 |
| Paula Green SVP of Human Resources | Aug 21, 2026 | Sale | −1,360 | $139.07 | $189.14K | 117,921 |
| Dennis Cho See Remarks | Aug 19, 2026 | Sale(10b5-1 plan) | −14,205 | $129.75 | $1.84M | 75,661 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −33,354 | $115.90 | $3.87M | 259,679 |
| Patrick John Finn President and COO | Aug 18, 2026 | Option exercise | +23,355 | $67.85 | $1.58M | 293,033 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −10,420 | $116.82 | $1.22M | 249,259 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −8,868 | $117.70 | $1.04M | 240,391 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −4,500 | $119.04 | $535.68K | 235,891 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −12,917 | $119.86 | $1.55M | 222,974 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −6,296 | $121.01 | $761.88K | 216,678 |
| Patrick John Finn President and COO | Aug 18, 2026 | Sale(10b5-1 plan) | −2,000 | $122.58 | $245.16K | 214,678 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 12, 2026 | Sale(10b5-1 plan) | −19,952 | $125.08 | $2.50M | 818,938 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 12, 2026 | Option exercise | +19,952 | $26.66 | $531.92K | 838,890 |
| Katryn Blake Director | Aug 12, 2026 | Sale | −2,240 | $122.88 | $275.25K | 17,208 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 10, 2026 | Option exercise | +113,318 | $26.66 | $3.02M | 932,256 |
| Emily M. Leproust Chief Executive Officer, Director | Aug 10, 2026 | Sale(10b5-1 plan) | −113,318 | $125.16 | $14.18M | 818,938 |
| Robert Chess Director | Aug 7, 2026 | Sale(10b5-1 plan) | −18,417 | $110.89 | $2.04M | 21,084 |
| Robert Chess Director | Aug 7, 2026 | Option exercise | +18,417 | $11.89 | $218.98K | 39,501 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.
Planned insider sales
Notices of proposed sale filed on Form 144 before shares are sold
| Seller | Filed | Shares | Market value | Planned sale | Acquired through |
|---|---|---|---|---|---|
| Adam Laponis Officer | Oct 9, 2026 | 2,462 | $384.82K | Oct 9, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Oct 5, 2026 | 4,548 | $919.37K | Oct 5, 2026 | Restricted Stock Vesting |
| Patrick John Finn Officer | Oct 2, 2026 | 25,714 | $4.86M | Oct 2, 2026 | Restricted Stock Vesting |
| Adam Laponis Officer | Oct 2, 2026 | 8,057 | $1.52M | Oct 2, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Oct 2, 2026 | 45,736 | $8.64M | Oct 2, 2026 | Restricted Stock Vesting |
| Dennis Cho Officer | Oct 2, 2026 | 9,514 | $1.80M | Oct 2, 2026 | Restricted Stock Vesting |
| Robert F. Werner Officer | Oct 2, 2026 | 1,482 | $279.93K | Oct 2, 2026 | Restricted Stock Vesting |
| Paula Green Officer | Oct 2, 2026 | 10,088 | $1.91M | Oct 2, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Oct 1, 2026 | 655 | $131.00K | Oct 1, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Sep 24, 2026 | 5,203 | $922.91K | Sep 24, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Sep 21, 2026 | 1,687 | $279.18K | Sep 21, 2026 | Restricted Stock Vesting |
| Dennis Cho Officer | Sep 21, 2026 | 348 | $57.59K | Sep 21, 2026 | Restricted Stock Vesting |
| Paula Green Officer | Sep 21, 2026 | 294 | $48.65K | Sep 21, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Sep 17, 2026 | 295,037 | $44.68M | Sep 17, 2026 | Restricted Stock Vesting |
| Emily M. Leproust Officer, Director | Sep 17, 2026 | 61,509 | $9.31M | Sep 17, 2026 | Restricted Stock Vesting |