OKURNasdaqPharmaceutical PreparationsFiscal year ends December 31
OnKure Therapeutics, Inc.
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 4, 2026
$2.25+0.15 (+7.14%)
Close on Oct 19, 2026
- Market cap
- $112.21M
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
86.3%
35M of 40M shares
Institutional holders
75
32 new, 8 sold out
Net institutional buying
7M
In Q2 2026
Insider trades, 12 months
0 buys · 8 sales
Net sold $5.63K
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| Access Industries Holdings LLC | 9,091,532 | 19.99% | 13D (active) | Mar 31, 2026 |
| Shay Capital Holdings LLC | 810,214 | 6.30% | 13G (passive) | May 15, 2025 |
| Prosight Partners, LLC | 745,649 | 5.80% | 13G (passive) | Nov 24, 2025 |
| CF Group Management, Inc. | 669,539 | 5.20% | 13G (passive) | Jun 30, 2025 |
| RA Capital Management, L.P. | 4,038,715 | 9.90% | 13G (passive) | Mar 31, 2026 |
| Anders Hove | 3,924,037 | 9.50% | 13G (passive) | Mar 27, 2026 |
| Lampert Mark N | 3,235,778 | 8.00% | 13G (passive) amendment | Jun 30, 2026 |
| Kevin Tang | 2,946,260 | 8.80% | 13G (passive) | Sep 26, 2024 |
| Coastlands Capital GP LLC | 2,700,000 | 6.67% | 13G (passive) | Oct 1, 2026 |
| StepStone VC MI-G GP, LLC | 2,660,612 | 6.60% | 13G (passive) | Mar 31, 2026 |
| Daniel Schneeberger | 2,238,684 | 5.50% | 13G (passive) amendment | Jun 30, 2026 |
| Bvf Inc/Il | 2,134,908 | 5.30% | 13G (passive) | May 19, 2026 |
| ADAR1 Capital Management, LLC | 1,014,158 | 7.90% | 13G (passive) | Dec 31, 2025 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of OKUR | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 3,998,333 | 9.87% | $18.23M | – | 0.16% |
| Bvf Inc/Il | 3,235,778 | 7.99% | $14.76M | +1,256,806 | 0.38% |
| Acorn Capital Advisors, LLC | 2,839,674 | 7.01% | $12.95M | – | 3.53% |
| StepStone Group LP | 2,660,612 | 6.57% | $12.13M | – | 0.56% |
| ADAR1 Capital Management, LLC | 2,238,684 | 5.53% | $10.21M | −196,257 | 0.47% |
| Vivo Capital, LLC | 1,927,710 | 4.76% | $8.79M | – | 0.80% |
| Vestal Point Capital, LP | 1,825,699 | 4.51% | $8.33M | −14,120 | 0.19% |
| BlackRock, Inc. | 1,499,845 | 3.70% | $6.84M | +1,450,258 | 0.00% |
| Trails Edge Capital Partners, LP | 1,438,456 | 3.55% | $6.56M | New | 1.04% |
| Vanguard Capital Management LLC | 1,437,039 | 3.55% | $6.55M | +854,562 | 0.00% |
| Adage Capital Partners Gp, L.L.C. | 1,204,819 | 2.98% | $5.49M | – | 0.01% |
| Citadel Advisors LLC | 1,187,047 | 2.93% | $5.41M | +1,149,460 | 0.00% |
| Sio Capital Management, LLC | 1,078,965 | 2.66% | $4.92M | – | 0.81% |
| Prosight Management, LP | 978,992 | 2.42% | $4.46M | −1,175,389 | 0.77% |
| Logos Global Management LP | 963,855 | 2.38% | $4.40M | New | 0.19% |
| Geode Capital Management, LLC | 724,438 | 1.79% | $3.30M | +625,688 | 0.00% |
| NEA Management Company, LLC | 478,548 | 1.18% | $2.18M | – | 0.14% |
| State Street Corp | 463,662 | 1.14% | $2.11M | +450,200 | 0.00% |
| Ensign Peak Advisors, Inc | 431,631 | 1.07% | $1.97M | New | 0.00% |
| Renaissance Technologies LLC | 358,738 | 0.89% | $1.64M | −18,512 | 0.00% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 75 | 35M | 86.3% | 32 / 21 | 9 / 8 | 11M | 4M |
| Q1 2026 | 51 | 28M | 68.0% | 18 / 12 | 14 / 8 | 20M | 2M |
| Q4 2025 | 43 | 11M | 27.3% | 7 / 9 | 16 / 6 | 3M | 2M |
| Q3 2025 | 42 | 10M | 25.2% | 1 / 15 | 13 / 8 | 0M | 1M |
| Q2 2025 | 49 | 11M | 26.6% | 8 / 16 | 13 / 6 | 4M | 5M |
| Q1 2025 | 47 | 12M | 29.5% | 4 / 15 | 13 / 8 | 1M | 1M |
| Q4 2024 | 51 | 12M | 29.2% | 51 / 0 | 0 / 1 | 12M | 0M |
| Q3 2024 | 1 | 0M | 0.0% | 1 / 0 | 0 / 0 | 0M | 0M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of OKUR | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 1,109,823 | 2.74% | $5.06M | 0.00% | Jun 30, 2026 |
| iShares Russell 2000 ETF | 483,134 | 1.19% | $2.20M | 0.00% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 302,423 | 0.75% | $1.38M | 0.00% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund | 285,510 | 0.71% | $1.09M | 0.00% | Jul 31, 2026 |
| iShares Russell 2000 Value ETF | 193,829 | 0.48% | $883.86K | 0.01% | Jun 30, 2026 |
| iShares Micro-Cap ETF | 79,084 | 0.20% | $360.62K | 0.02% | Jun 30, 2026 |
| Schwab Small-Cap Index Fund | 63,640 | 0.16% | $243.10K | 0.00% | Jul 31, 2026 |
| Master Small Cap Index Series | 41,652 | 0.10% | $189.93K | 0.00% | Jun 30, 2026 |
| Fidelity Small Cap Value Index Fund | 36,563 | 0.09% | $166.73K | 0.01% | Jun 30, 2026 |
| Fidelity Extended Market Index Fund | 36,530 | 0.09% | $153.43K | 0.00% | May 31, 2026 |
| Nuveen Small Cap Blend Index Fund | 35,402 | 0.09% | $135.24K | 0.00% | Jul 31, 2026 |
| Ultra-Small Company Market Fund | 34,000 | 0.08% | $155.04K | 0.10% | Jun 30, 2026 |
| Dimensional U.S. Small Cap ETF | 32,426 | 0.08% | $123.87K | 0.00% | Jul 31, 2026 |
| EQ/2000 Managed Volatility Portfolio | 22,417 | 0.06% | $102.22K | 0.00% | Jun 30, 2026 |
| LVIP State Street Small-Cap Index Fund | 20,500 | 0.05% | $93.48K | 0.00% | Jun 30, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| Nicholas A. Saccomano | President and CEO, Director | 11,160 | 0.03% | Sep 23, 2026 |
| Jason A. Leverone | Chief Financial Officer | 18,500 | 0.05% | Sep 23, 2026 |
| Dylan Hartley | Chief Scientific Officer | – | – | Aug 11, 2026 |
| Samuel Agresta | Chief Medical Officer | – | – | Aug 11, 2026 |
| Isaac Manke | Director | 20,583 | 0.05% | Aug 13, 2026 |
| Andrew John Phillips | Director | – | – | Aug 11, 2026 |
| Michael G. Grey | Director | 494,762 | 1.22% | Aug 11, 2026 |
| R. Michael Carruthers | Director | 874 | 0.00% | Aug 11, 2026 |
| Liam Ratcliffe | Director | – | – | Aug 11, 2026 |
| Valerie Malyvanh Jansen | Director | – | – | Aug 11, 2026 |
| Edward T. Mathers | Director | 15,310 | 0.04% | Aug 11, 2026 |
| Access Industries Management, Llc | 10% owner | 3,998,332 | 9.87% | Apr 7, 2026 |
| Biotechnology LLC AI | 10% owner | – | – | Apr 7, 2026 |
| Industries Holdings LLC Access | 10% owner | – | – | Apr 7, 2026 |
| Len Blavatnik | 10% owner | – | – | Apr 7, 2026 |
| Acorn Bioventures 2, L.P. | 10% owner | – | – | May 27, 2025 |
| Acorn Capital Advisors GP 2, LLC | 10% owner | 1,129,730 | 2.79% | May 27, 2025 |
| Anders D. Hove | 10% owner | – | – | May 19, 2025 |
| Private Healthcare Fund III LP Cormorant | – | 0 | – | May 19, 2025 |
| Cormorant Global Healthcare Master Fund, LP | – | 1,813,439 | 4.48% | May 19, 2025 |
| Private Healthcare Fund V. LP Cormorant | – | – | – | May 19, 2025 |
| Private Healthcare Fund IV LP Cormorant | – | – | – | May 19, 2025 |
| Acorn Capital Advisors Gp, Llc | 10% owner | 4,279,348 | 10.57% | May 19, 2025 |
| Acorn Bioventures, L.P. | 10% owner | – | – | May 19, 2025 |
| Bihua Chen | – | – | – | May 19, 2025 |
| Cormorant Asset Management, LP | – | – | – | May 19, 2025 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Nicholas A. Saccomano President and CEO, Director | Sep 21, 2026 | Sale | −87 | $2.97 | $258 | 11,160 |
| Jason A. Leverone Chief Financial Officer | Sep 21, 2026 | Sale | −302 | $2.97 | $897 | 18,500 |
| Nicholas A. Saccomano President and CEO, Director | Jun 22, 2026 | Sale | −86 | $4.40 | $378 | 11,247 |
| Jason A. Leverone Chief Financial Officer | Jun 22, 2026 | Sale | −303 | $4.40 | $1.33K | 18,802 |
| Jason A. Leverone Chief Financial Officer | Mar 23, 2026 | Sale | −301 | $4.16 | $1.25K | 16,000 |
| Nicholas A. Saccomano President and CEO, Director | Mar 23, 2026 | Sale | −86 | $4.16 | $358 | 7,333 |
| Isaac Manke Director | Dec 31, 2025 | Award | +5,258 | – | – | 20,583 |
| Edward T. Mathers Director | Dec 31, 2025 | Award | +3,911 | – | – | 15,310 |
| Nicholas A. Saccomano President and CEO, Director | Dec 22, 2025 | Sale | −87 | $2.97 | $258 | 7,419 |
| Jason A. Leverone Chief Financial Officer | Dec 22, 2025 | Sale | −302 | $2.97 | $897 | 16,301 |
| Isaac Manke Director | Sep 30, 2025 | Award | +5,545 | – | – | 15,325 |
| Edward T. Mathers Director | Sep 30, 2025 | Award | +4,125 | – | – | 11,399 |
| Nicholas A. Saccomano President and CEO, Director | Sep 22, 2025 | Sale | −88 | $2.62 | $231 | 3,506 |
| Jason A. Leverone Chief Financial Officer | Sep 22, 2025 | Sale | −303 | $2.62 | $794 | 12,603 |
| Edward T. Mathers Director | Jun 30, 2025 | Award | +4,694 | – | – | 7,274 |
| Isaac Manke Director | Jun 30, 2025 | Award | +6,311 | – | – | 9,780 |
| Nicholas A. Saccomano President and CEO, Director | Jun 23, 2025 | Sale | −88 | $2.38 | $209 | 3,594 |
| Jason A. Leverone Chief Financial Officer | Jun 23, 2025 | Sale | −303 | $2.38 | $721 | 12,906 |
| Acorn Capital Advisors Gp, Llc 10% owner | May 15, 2025 | Buy | +270,270 | $1.85 | $500.00K | 1,709,944 |
| Acorn Capital Advisors Gp, Llc 10% owner | May 15, 2025 | Buy | +1,129,730 | $1.85 | $2.09M | 1,129,730 |
| Private Healthcare Fund III LP Cormorant – | May 15, 2025 | Sale | −1,813,439 | $1.85 | $3.35M | 0 |
| Cormorant Global Healthcare Master Fund, LP 10% owner | May 12, 2025 | Sale | −24,300 | $1.99 | $48.36K | 1,813,439 |
| Nicholas A. Saccomano President and CEO, Director | Apr 7, 2025 | Sale | −516 | $2.67 | $1.38K | 3,682 |
| Jason A. Leverone Chief Financial Officer | Apr 7, 2025 | Sale | −1,844 | $2.67 | $4.92K | 13,209 |
| Nicholas A. Saccomano President and CEO, Director | Apr 4, 2025 | Sale | −358 | $3.33 | $1.19K | 4,198 |
| Jason A. Leverone Chief Financial Officer | Apr 4, 2025 | Sale | −1,278 | $3.33 | $4.26K | 15,053 |
| Isaac Manke Director | Mar 31, 2025 | Award | +3,469 | – | – | 3,469 |
| Edward T. Mathers Director | Mar 31, 2025 | Award | +2,580 | – | – | 2,580 |
| Braden Michael Leonard – | Oct 7, 2024 | Other | +345,739 | – | – | 345,739 |
| Braden Michael Leonard – | Oct 7, 2024 | Other | +102,076 | – | – | 102,076 |
| Jason A. Leverone Chief Financial Officer | Oct 4, 2024 | Award | +16,331 | – | – | 16,331 |
| Nicholas A. Saccomano President and CEO, Director | Oct 4, 2024 | Award | +4,556 | – | – | 4,556 |
| R. Michael Carruthers Director | Oct 4, 2024 | Award | +874 | – | – | 874 |
| R. Michael Carruthers Director | Oct 4, 2024 | Award | +4,065 | – | – | 4,939 |
| Braden Michael Leonard 10% owner | Sep 25, 2024 | Buy | +68,746 | $1.50 | $103.12K | 3,457,395 |
| Braden Michael Leonard 10% owner | Sep 24, 2024 | Buy | +29,600 | $1.41 | $41.74K | 3,388,649 |
| Braden Michael Leonard 10% owner | Sep 18, 2024 | Buy | +806 | $1.40 | $1.13K | 3,359,049 |
| Braden Michael Leonard 10% owner | Sep 17, 2024 | Buy | +55,300 | $1.36 | $75.21K | 3,358,243 |
| Braden Michael Leonard 10% owner | Sep 16, 2024 | Buy | +172,747 | $1.37 | $236.66K | 3,302,943 |
| Braden Michael Leonard 10% owner | Sep 13, 2024 | Buy | +150,000 | $1.31 | $196.50K | 3,130,196 |
| Braden Michael Leonard 10% owner | Sep 12, 2024 | Buy | +36,176 | $1.40 | $50.65K | 2,980,196 |
| Braden Michael Leonard 10% owner | Aug 14, 2024 | Buy | +100,487 | $1.41 | $141.69K | 2,944,020 |
| Braden Michael Leonard 10% owner | Aug 13, 2024 | Buy | +171,339 | $1.39 | $238.16K | 2,843,533 |
| Braden Michael Leonard 10% owner | May 14, 2024 | Buy | +335,000 | $1.54 | $515.90K | 2,672,194 |
| Braden Michael Leonard 10% owner | May 14, 2024 | Buy | +79,281 | $1.56 | $123.68K | 2,337,194 |
| Ashley Hall Chief Development Officer | Aug 28, 2023 | Option exercise | +15,625 | $1.80 | $28.13K | 55,225 |
| Ashley Hall Chief Development Officer | Aug 28, 2023 | Sale | −15,625 | $6.28 | $98.13K | 39,600 |
| Michael G. Grey Executive Chairman, Director | Jul 26, 2023 | Gift | −50,000 | – | – | 0 |
| Holdings A/S Novo 10% owner | Jun 23, 2023 | Sale | −100,000 | $7.10 | $710.00K | 3,330,337 |
| Niall O'Donnell Director | May 8, 2023 | Buy | +125,000 | $8.00 | $1.00M | 2,188,713 |
| Michael Cruse Chief Operating Officer | Sep 1, 2022 | Buy | +7,500 | $3.39 | $25.43K | 13,697 |
| Michael G. Grey Executive Chairman, Director | Aug 31, 2022 | Option exercise | +50,000 | $1.97 | $98.50K | 50,000 |
| Michael Cruse Chief Operating Officer | Aug 31, 2022 | Buy | +3,212 | $3.21 | $10.31K | 6,197 |
| Michael Cruse Chief Operating Officer | Aug 30, 2022 | Buy | +1,845 | $3.19 | $5.89K | 2,985 |
| Michael Cruse Chief Operating Officer | Aug 30, 2022 | Buy | +975 | $3.16 | $3.08K | 31,758 |
| Michael Cruse Chief Operating Officer | Aug 29, 2022 | Buy | +1,140 | $3.24 | $3.69K | 1,140 |
| Michael Cruse Chief Operating Officer | Aug 29, 2022 | Buy | +83 | $3.24 | $269 | 30,783 |
| Alejandro Dorenbaum Chief Medical Officer | Aug 12, 2022 | Gift | −22,348 | – | – | 30,000 |
| Alejandro Dorenbaum Chief Medical Officer | Dec 10, 2021 | Award | +30,000 | – | – | 52,348 |
| Michael Cruse Senior VP-Corporate Operations | Dec 10, 2021 | Award | +25,000 | – | – | 29,100 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.
Planned insider sales
Notices of proposed sale filed on Form 144 before shares are sold
| Seller | Filed | Shares | Market value | Planned sale | Acquired through |
|---|---|---|---|---|---|
| Ashley Hall Officer | Aug 28, 2023 | 15,625 | $98.06K | Aug 28, 2023 | STOCK OPTION EXERCISE |
| Holdings A/S Novo 10% Stockholder | Jun 23, 2023 | 100,000 | $735.00K | Jun 23, 2023 | Purchase of stock in the Issuer's IPO |