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Karyopharm Therapeutics Inc. logo

Karyopharm Therapeutics Inc. (KPTIQ) shareholders

KPTIQPharmaceutical PreparationsFiscal year ends December 31Also trades as KPTI
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 13, 2026Score 0/30
Share price
Not available yet

Price, market cap and P/E appear here once daily prices are connected.

Ownership

Who owns Karyopharm Therapeutics's shares

Held by institutions
–
Shares held, 13F filers
Institutional holders
–
Net institutional buying
–
Insider trades, 12 months
0 buys · 21 sales
Net sold $351.42K

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Peter Kolchinsky
Joint filing with RA Capital Management, L.P. (9.90%), Rajeev Shah (9.90%) and 1 more
2,302,5049.90%13G (passive) amendmentJun 30, 2026
Rajeev Shah
Joint filing with RA Capital Management, L.P. (9.90%), Peter Kolchinsky (9.90%) and 1 more
2,078,9139.90%13G (passive)Mar 26, 2026
Affinity Asset Advisors, LLC
Joint filing with Michael Cho (8.60%)
2,073,5178.60%13G (passive) amendmentMar 31, 2026
Commodore Capital Master LP
Joint filing with Commodore Capital LP (9.90%), Robert Egen Atkinson (9.90%) and 1 more
1,950,0009.90%13G (passive)Mar 26, 2026
Michael Cho
Joint filing with Affinity Asset Advisors, LLC (8.60%)
1,713,0928.60%13G (passive) amendmentJan 22, 2026
Opaleye Management Inc.
Joint filing with Opaleye, L.P. (9.48%), James Silverman (9.48%)
1,569,0029.48%13G (passive)Oct 10, 2025
T. Rowe Price Investment Management, Inc.1,539,1476.60%13G (passive) amendmentMay 31, 2026
Robert Atchinson
Joint filing with Adage Capital Management, L.P. (6.78%), Phillip Gross (6.78%)
1,536,7366.78%13G (passive) amendmentJun 30, 2026
Israel A. Englander
Joint filing with Integrated Core Strategies (US) LLC (5.70%), Millennium Management LLC (5.70%) and 1 more
1,297,2975.70%13G (passive)Aug 31, 2026
BlackRock, Inc.1,266,0845.60%13G (passive)Jun 30, 2026
Affinity Healthcare Fund, LP
Joint filing with Affinity Asset Advisors, LLC (7.83%)
664,2247.83%13G (passive)Apr 3, 2025

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares ownedLatest filing
Richard A. PaulsonPresident and CEO, Director269,747May 15, 2026
Kristin AbateChief Accounting Officer18,616Oct 19, 2026
Stuart PoultonEVP, Chief Development Officer94,632Jul 30, 2026
Reshma RangwalaEVP & Chief Medical Officer56,829May 15, 2026
Sohanya Roshan ChengEVP & Chief Commercial Officer107,940May 15, 2026
Michael ManoEVP, CLO&Secretary94,398May 15, 2026
Lori MacomberEVP, CFO & Treasurer85,105Feb 4, 2026
Christy J. OligerDirector15,508May 26, 2026
Chen SchorDirector15,508May 26, 2026
Barry E. GreeneDirector16,415May 26, 2026
Garen G. BohlinDirector18,517May 26, 2026
Deepika PakianathanDirector15,508May 26, 2026
Zhen SuDirector15,508May 26, 2026
Mansoor Raza MirzaDirector17,121May 29, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
Kristin Abate
Chief Accounting Officer
Oct 16, 2026Sale−4,788$0.34$1.65K18,616
Kristin Abate
Chief Accounting Officer
Oct 1, 2026Sale−378$1.19$45023,404
Kristin Abate
Chief Accounting Officer
Sep 1, 2026Sale−19$2.02$3823,782
Stuart Poulton
EVP, Chief Development Officer
Jul 28, 2026Sale−189$7.10$1.34K94,632
Christy J. Oliger
Director
May 21, 2026Award+15,508––15,508
Garen G. Bohlin
Director
May 21, 2026Award+15,508––18,517
Zhen Su
Director
May 21, 2026Award+15,508––15,508
Chen Schor
Director
May 21, 2026Award+15,508––15,508
Deepika Pakianathan
Director
May 21, 2026Award+15,508––15,508
Barry E. Greene
Director
May 21, 2026Award+15,508––16,415
Stuart Poulton
EVP, Chief Development Officer
May 14, 2026Sale−403$9.50$3.83K94,821
Kristin Abate
Chief Accounting Officer
May 14, 2026Sale−53$9.50$50423,801
Michael Mano
EVP, CLO&Secretary
May 14, 2026Sale−266$9.50$2.53K94,398
Richard A. Paulson
President and CEO, Director
May 14, 2026Sale−2,203$9.50$20.93K269,747
Reshma Rangwala
EVP & Chief Medical Officer
May 14, 2026Sale−408$9.50$3.88K56,829
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
May 14, 2026Sale−324$9.50$3.08K107,940
Stuart Poulton
EVP, Chief Development Officer
May 13, 2026Award+896––95,224
Kristin Abate
Chief Accounting Officer
May 13, 2026Award+121––23,854
Michael Mano
EVP, CLO&Secretary
May 13, 2026Award+700––94,664
Richard A. Paulson
President and CEO, Director
May 13, 2026Award+4,920––271,950
Reshma Rangwala
EVP & Chief Medical Officer
May 13, 2026Award+947––57,237
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
May 13, 2026Award+947––108,264
Reshma Rangwala
EVP & Chief Medical Officer
Apr 21, 2026Sale−449$8.94$4.01K56,290
Stuart Poulton
EVP, Chief Development Officer
Mar 2, 2026Sale−5,101$9.41$48.00K94,328
Kristin Abate
Chief Accounting Officer
Mar 2, 2026Sale−559$9.41$5.26K22,063
Michael Mano
EVP, CLO&Secretary
Mar 2, 2026Sale−3,526$9.41$33.18K93,964
Richard A. Paulson
President and CEO, Director
Mar 2, 2026Sale−12,361$9.41$116.32K267,030
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
Mar 2, 2026Sale−4,604$9.41$43.32K107,317
Reshma Rangwala
EVP & Chief Medical Officer
Mar 2, 2026Sale−5,066$9.41$47.67K56,739
Stuart Poulton
EVP, Chief Development Officer
Feb 17, 2026Sale−378$8.63$3.26K99,429
Richard A. Paulson
President and CEO, Director
Feb 5, 2026Award+81,060––279,391
Lori Macomber
EVP, CFO & Treasurer
Feb 3, 2026Sale−1,626$6.30$10.24K85,105
Lori Macomber
EVP, CFO & Treasurer
Jan 31, 2026Award+32,415––86,731
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
Jan 31, 2026Award+32,415––111,921
Michael Mano
EVP, CLO&Secretary
Jan 31, 2026Award+32,415––97,490
Stuart Poulton
EVP, Chief Development Officer
Jan 31, 2026Award+32,415––99,807
Reshma Rangwala
EVP & Chief Medical Officer
Jan 31, 2026Award+32,415––61,805
Kristin Abate
Chief Accounting Officer
Jan 28, 2026Sale−50$7.03$35222,622
Kristin Abate
Chief Accounting Officer
Jan 27, 2026Award+92––22,672
Kristin Abate
Chief Accounting Officer
Jan 21, 2026Sale−265$5.96$1.58K22,580
Richard A. Paulson
President and CEO, Director
Oct 15, 2025Award+114,285––198,331
Michael Mano
SVP, General Counsel&Secretary
Oct 15, 2025Award+43,650––65,075
Lori Macomber
EVP, CFO & Treasurer
Oct 15, 2025Award+43,650––54,316
Kristin Abate
Chief Accounting Officer
Oct 15, 2025Award+12,799––22,845
Stuart Poulton
EVP, Chief Development Officer
Oct 15, 2025Award+39,682––67,392
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
Oct 15, 2025Award+43,650––79,506
Kristin Abate
Chief Accounting Officer
Oct 1, 2025Sale−362$6.30$2.28K10,046
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
Sep 15, 2025Sale−325$6.43$2.09K35,856
Richard A. Paulson
President and CEO, Director
Sep 15, 2025Sale−1,257$6.43$8.08K84,046
Michael Mano
SVP, General Counsel&Secretary
Sep 15, 2025Sale−234$6.43$1.50K21,425
Kristin Abate
Chief Accounting Officer
Sep 15, 2025Sale−23$6.43$14810,408
Stuart Poulton
EVP, Chief Development Officer
Sep 15, 2025Sale−401$6.43$2.58K27,710
Reshma Rangwala
EVP & Chief Medical Officer
Sep 15, 2025Sale−408$6.43$2.62K29,390
Sohanya Roshan Cheng
EVP & Chief Commercial Officer
Sep 12, 2025Award+945––36,181
Richard A. Paulson
President and CEO, Director
Sep 12, 2025Award+2,800––85,303
Michael Mano
SVP, General Counsel&Secretary
Sep 12, 2025Award+612––21,659
Kristin Abate
Chief Accounting Officer
Sep 12, 2025Award+46––10,431
Stuart Poulton
EVP, Chief Development Officer
Sep 12, 2025Award+888––28,111
Reshma Rangwala
EVP & Chief Medical Officer
Sep 12, 2025Award+945––29,798
Kristin Abate
Chief Accounting Officer
Sep 3, 2025Sale−12$6.78$819,463

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

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