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Karyopharm Therapeutics Inc. (KPTIQ) company profile

KPTIQPharmaceutical PreparationsFiscal year ends December 31Also trades as KPTI
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 13, 2026Score 0/30
Share price
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About Karyopharm Therapeutics

Pharmaceutical Preparations, SIC 2834

Karyopharm Therapeutics Inc. is a pharmaceutical company that focuses on the discovery, development, and commercialization of treatments such as Xpovio. Operating within the healthcare sector, the business develops product candidates and enters into commercial collaborations and licensing agreements with partner firms, including Menarini and Antengene Therapeutics. Through these arrangements, the company provides products and licenses its pharmaceutical assets to partners and customers across the industry.

The company maintains operational activities in the United States and works with international licensing partners. Its principal executive offices and headquarters are located at 85 Wells Avenue, 2nd Floor, in Newton, Massachusetts. In addition, the organization leases dedicated office and research space to conduct its operations and support its business initiatives.

Summary of the business section of Karyopharm Therapeutics's latest annual report, written by StockData.

Company profile

Company

Legal name
Karyopharm Therapeutics Inc.
Founded
2008
Headquarters
Newton, MA
Address
85 Wells Avenue, Second Floor 02459
Phone
(617) 658-0600
Employees
228, Dec 31, 2025
Industry
Pharmaceutical Preparations
Incorporated in
Delaware
Fiscal year ends
December 31
Auditor
Ernst & Young LLP, Boston, Massachusetts

Stock & identifiers

Ticker
KPTIQ
Other tickers
KPTI
IPO date
Nov 7, 2013
Shares outstanding
23M, Aug 6, 2026
Public float
$37.00M, Jun 30, 2025
Filer category
Non-accelerated filer<br>Smaller reporting company
Stock splits
1-for-15 reverse, Feb 26, 2025
SEC CIK
1503802
CUSIP
48576U205
ISIN
US48576U2050
LEI
549300J1VANRCNTYST87
EIN
26-3931704

Executives and directors

Officers and directors who filed ownership reports (Forms 3, 4, 5) in the last two years

NamePositionShares owned
Richard A. PaulsonPresident and CEO, Director269,747
Kristin AbateChief Accounting Officer18,616
Stuart PoultonEVP, Chief Development Officer94,632
Reshma RangwalaEVP & Chief Medical Officer56,829
Sohanya Roshan ChengEVP & Chief Commercial Officer107,940
Michael ManoEVP, CLO&Secretary94,398
Lori MacomberEVP, CFO & Treasurer85,105
Christy J. OligerDirector15,508
Chen SchorDirector15,508
Barry E. GreeneDirector16,415
Garen G. BohlinDirector18,517
Deepika PakianathanDirector15,508
Zhen SuDirector15,508
Mansoor Raza MirzaDirector17,121

CEO pay and shareholder return

Pay versus performance table from the proxy statement

Fiscal yearCEO total payCEO pay actually paidOther executives (avg)Value of $100 investedPeer group
FY2025$2.32M$2.12M$1.71M$14–
FY2024$2.07M$1.65M$1.11M$20–
FY2023$2.63M$35.74K$1.17M$25–
FY2022
Dr Kauffman
$0$0$2.89M$53–
FY2022
Mr Paulson
$6.91M$1.56M$2.89M$53–
FY2021$3.07M-$1.07M$2.00M$34$126

“Actually paid” adjusts reported pay for changes in the value of equity awards. Shareholder return assumes $100 invested at the start of the measurement period, as disclosed by the company.

Executive compensation, fiscal 2025

Summary compensation table from the latest proxy statement

ExecutiveSalaryBonusStock awardsOption awardsIncentive payOtherTotalvs. prior year
Richard Paulson
President and Chief Executive Officer
$770.00K$100.10K$839.00K$241.54K$350.35K$19.91K$2.32M+12%
Stuart Poulton
Executive Vice President, Chief Development Officer
$500.14K$295.01K$312.29K$115.74K$157.54K$18.86K$1.40M–
Reshma Rangwala
Chief Medical Officer and Head of Research
$567.74K$1.05M$79.49K$120.77K$178.84K$18.21K$2.02M+79%

Stock and option awards are grant-date fair values, not realized pay. “Other” includes pension value changes and all other compensation. Source proxy statement.

IPO

From the final prospectus (Form 424B4) and the first day of trading

Offering

Type
Initial public offering
Final prospectus filed
Nov 7, 2013
Offer price
$16.00
Securities offered
6,800,000
Gross proceeds
$108.80M
Exchange
Nasdaq
First trading day
Nov 6, 2013
First-day close
$16.05+0.3%
Lock-up ends (est.)
May 5, 2014

“Per Share Total Public offering price $16.00 $108,800,000 Underwriting discount(1) $1.12 $7,616,000 Proceeds, before expenses, to us $14.88 $101,184,000 (1) We refer you to "Underwriting" on page 165 for additional information regarding total underwriting compensation.”

Lock-up end is estimated as 180 days after the first trading day; the prospectus sets the actual terms.

Employees

Headcount reported in annual reports

“As of February 5, 2026, we had 228 employees, all of whom were full-time employees.”

Corporate history

Events identified from SEC filings

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