XERSNasdaqPharmaceutical PreparationsFiscal year ends December 31
Xeris Biopharma Holdings, Inc.
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 6, 2026
$10.95+0.64 (+6.21%)
Close on Oct 19, 2026
- Market cap
- $1.89B
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
59.4%
108M of 182M shares
Institutional holders
239
35 new, 28 sold out
Net institutional buying
3M
In Q2 2026
Insider trades, 12 months
0 buys · 30 sales
Net sold $5.01M
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| Vanguard Capital Management | 8,637,640 | 5.00% | 13G (passive) | Jun 30, 2026 |
| BlackRock, Inc. | 10,011,391 | 7.20% | 13G (passive) | Dec 31, 2023 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of XERS | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| BlackRock, Inc. | 14,525,539 | 7.97% | $115.04M | +1,579,754 | 0.00% |
| D. E. Shaw & Co., Inc. | 7,804,758 | 4.28% | $61.81M | +15,947 | 0.03% |
| Vanguard Capital Management LLC | 7,340,229 | 4.03% | $58.13M | +359,347 | 0.00% |
| State Street Corp | 4,821,566 | 2.64% | $38.19M | +163,392 | 0.00% |
| Geode Capital Management, LLC | 4,718,183 | 2.59% | $37.37M | +427,554 | 0.00% |
| Nuveen, LLC | 4,385,141 | 2.41% | $34.73M | +1,468,543 | 0.01% |
| Rosalind Advisors, Inc. | 2,908,981 | 1.60% | $23.04M | −322,719 | 8.56% |
| Qube Research & Technologies Ltd | 2,893,749 | 1.59% | $22.92M | −1,220,676 | 0.02% |
| Vanguard Portfolio Management LLC | 2,626,208 | 1.44% | $20.80M | −39,400 | 0.00% |
| Wellington Management Group Llp | 2,365,103 | 1.30% | $18.73M | +193,749 | 0.00% |
| Morgan Stanley | 2,337,096 | 1.28% | $18.51M | −235,558 | 0.00% |
| Legal & General Group Plc | 2,012,792 | 1.10% | $15.94M | +104,503 | 0.00% |
| Armistice Capital, LLC | 1,958,702 | 1.07% | $15.51M | +48,864 | 0.19% |
| Two Sigma Investments, LP | 1,885,503 | 1.03% | $14.93M | −38,699 | 0.01% |
| Parkman Healthcare Partners LLC | 1,807,621 | 0.99% | $14.32M | +86,357 | 1.47% |
| Algert Global LLC | 1,742,942 | 0.96% | $13.80M | +585,984 | 0.16% |
| Northern Trust Corp | 1,597,749 | 0.88% | $12.65M | +153,132 | 0.00% |
| Goldman Sachs Group Inc | 1,594,072 | 0.87% | $12.63M | −19,578 | 0.00% |
| Aqr Capital Management LLC | 1,540,985 | 0.85% | $12.20M | +146,609 | 0.00% |
| Charles Schwab Investment Management Inc | 1,492,367 | 0.82% | $11.82M | +132,710 | 0.00% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 239 | 108M | 59.4% | 35 / 106 | 65 / 28 | 16M | 13M |
| Q1 2026 | 237 | 105M | 57.7% | 48 / 99 | 55 / 33 | 27M | 12M |
| Q4 2025 | 225 | 101M | 55.3% | 36 / 79 | 76 / 40 | 17M | 13M |
| Q3 2025 | 230 | 98M | 53.6% | 59 / 78 | 60 / 28 | 19M | 11M |
| Q2 2025 | 200 | 91M | 49.6% | 26 / 77 | 60 / 24 | 14M | 11M |
| Q1 2025 | 199 | 88M | 48.1% | 57 / 72 | 39 / 18 | 32M | 8M |
| Q4 2024 | 162 | 66M | 36.2% | 31 / 60 | 33 / 12 | 10M | 9M |
| Q3 2024 | 144 | 64M | 35.3% | 25 / 47 | 35 / 14 | 21M | 8M |
| Q2 2024 | 135 | 61M | 33.5% | 16 / 54 | 37 / 23 | 4M | 7M |
| Q1 2024 | 142 | 64M | 35.0% | 36 / 47 | 33 / 14 | 11M | 9M |
| Q4 2023 | 120 | 62M | 33.9% | 22 / 37 | 31 / 12 | 10M | 4M |
| Q3 2023 | 110 | 55M | 30.3% | 17 / 36 | 26 / 10 | 5M | 6M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of XERS | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 5,193,656 | 2.85% | $41.13M | 0.00% | Jun 30, 2026 |
| iShares Russell 2000 ETF | 4,455,457 | 2.44% | $35.29M | 0.04% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 1,986,461 | 1.09% | $15.73M | 0.02% | Jun 30, 2026 |
| College Retirement Equities Fund - Total Global Stock Account | 1,951,890 | 1.07% | $15.46M | 0.01% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund | 1,868,647 | 1.02% | $15.10M | 0.04% | Jul 31, 2026 |
| iShares Russell 2000 Growth ETF | 1,582,814 | 0.87% | $12.54M | 0.08% | Jun 30, 2026 |
| Nuveen Quant Small Cap Equity Fund | 1,199,820 | 0.66% | $9.69M | 0.24% | Jul 31, 2026 |
| First Trust Small Cap Growth AlphaDEX Fund | 886,418 | 0.49% | $7.16M | 0.55% | Jul 31, 2026 |
| Fidelity Extended Market Index Fund | 862,375 | 0.47% | $5.31M | 0.01% | May 31, 2026 |
| Vanguard Russell 2000 Index Fund | 817,453 | 0.45% | $5.04M | 0.03% | May 31, 2026 |
| Schwab U.S. Small-Cap ETF | 806,769 | 0.44% | $4.97M | 0.02% | May 31, 2026 |
| Nuveen Quant Small/Mid Cap Equity Fund | 797,160 | 0.44% | $6.44M | 0.24% | Jul 31, 2026 |
| State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF | 753,307 | 0.41% | $5.97M | 1.39% | Jun 30, 2026 |
| Janus Henderson Small/Mid Cap Growth Alpha ETF | 644,770 | 0.35% | $5.21M | 0.50% | Jul 31, 2026 |
| Federated Hermes MDT Small Cap Core Fund | 615,752 | 0.34% | $4.98M | 0.22% | Jul 31, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| John Patrick Shannon Jr | See Remarks, Director | 2,898,933 | 1.59% | Aug 21, 2026 |
| Kevin McCulloch | See Remarks | 1,639,208 | 0.90% | Sep 29, 2026 |
| Steven Pieper | See Remarks | 1,356,053 | 0.74% | Sep 1, 2026 |
| Beth Hecht | See Remarks | 1,127,796 | 0.62% | Sep 1, 2026 |
| Anh Tu Nguyen | See Remarks | 402,234 | 0.22% | Feb 25, 2026 |
| Kenneth Erland Johnson | See Remarks | 346,288 | 0.19% | Feb 3, 2025 |
| Nerissa Kreher | Director | 33,582 | 0.02% | Jul 2, 2026 |
| Barbara-Jean Anne Bormann-Kennedy | Director | 150,693 | 0.08% | Jun 5, 2026 |
| John Johnson | Director | 683,083 | 0.37% | Jun 5, 2026 |
| Dawn Halkuff | Director | 124,603 | 0.07% | Jun 5, 2026 |
| James Aloysius Brady | Director | 113,359 | 0.06% | Jun 5, 2026 |
| Marla Persky | Director | 157,063 | 0.09% | Jun 5, 2026 |
| Garheng Kong | Director | 238,337 | 0.13% | Jun 5, 2026 |
| Jeffrey W. Sherman | Director | 224,588 | 0.12% | Aug 29, 2025 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Kevin McCulloch See Remarks | Sep 28, 2026 | Sale(10b5-1 plan) | −25,000 | $10.00 | $250.00K | 1,614,208 |
| Kevin McCulloch See Remarks | Sep 1, 2026 | Sale(10b5-1 plan) | −15,000 | $8.49 | $127.35K | 1,639,208 |
| Beth Hecht See Remarks | Sep 1, 2026 | Sale(10b5-1 plan) | −16,666 | $8.49 | $141.49K | 1,127,796 |
| Steven Pieper See Remarks | Sep 1, 2026 | Sale(10b5-1 plan) | −5,000 | $8.50 | $42.50K | 1,356,053 |
| Steven Pieper See Remarks | Aug 12, 2026 | Sale(10b5-1 plan) | −5,000 | $8.50 | $42.50K | 1,361,053 |
| Beth Hecht See Remarks | Aug 3, 2026 | Sale(10b5-1 plan) | −16,666 | $8.01 | $133.49K | 1,144,462 |
| Kevin McCulloch See Remarks | Aug 3, 2026 | Sale(10b5-1 plan) | −15,000 | $8.02 | $120.30K | 1,676,126 |
| Kevin McCulloch See Remarks | Aug 1, 2026 | Tax withholding | −21,918 | $8.08 | $177.10K | 1,654,208 |
| John Patrick Shannon Jr See Remarks, Director | Aug 1, 2026 | Tax withholding | −36,645 | $8.08 | $296.09K | 2,898,933 |
| Steven Pieper See Remarks | Jul 7, 2026 | Sale(10b5-1 plan) | −27,600 | $8.52 | $235.15K | 1,366,053 |
| Steven Pieper See Remarks | Jul 6, 2026 | Sale(10b5-1 plan) | −17,400 | $8.50 | $147.90K | 1,393,653 |
| Beth Hecht See Remarks | Jul 1, 2026 | Sale(10b5-1 plan) | −16,666 | $8.03 | $133.83K | 1,161,128 |
| Nerissa Kreher Director | Jul 1, 2026 | Award | +33,582 | – | – | 33,582 |
| Kevin McCulloch See Remarks | Jul 1, 2026 | Sale(10b5-1 plan) | −90,000 | $8.03 | $722.70K | 1,691,126 |
| John Johnson Director | Jun 4, 2026 | Sale(10b5-1 plan) | −15,000 | $6.09 | $91.35K | 683,083 |
| John Johnson Director | Jun 4, 2026 | Award | +24,193 | – | – | 707,276 |
| Garheng Kong Director | Jun 4, 2026 | Award | +24,193 | – | – | 238,337 |
| Barbara-Jean Anne Bormann-Kennedy Director | Jun 4, 2026 | Award | +24,193 | – | – | 150,693 |
| Barbara-Jean Anne Bormann-Kennedy Director | Jun 4, 2026 | Sale(10b5-1 plan) | −16,000 | $6.09 | $97.44K | 126,500 |
| Dawn Halkuff Director | Jun 4, 2026 | Award | +24,193 | – | – | 119,193 |
| Dawn Halkuff Director | Jun 4, 2026 | Sale(10b5-1 plan) | −20,000 | $6.09 | $121.80K | 95,000 |
| Marla Persky Director | Jun 4, 2026 | Award | +24,193 | – | – | 150,693 |
| James Aloysius Brady Director | Jun 4, 2026 | Award | +24,193 | – | – | 113,359 |
| Marla Persky Director | Jun 3, 2026 | Sale(10b5-1 plan) | −15,500 | $5.90 | $91.45K | 126,500 |
| Beth Hecht See Remarks | Jun 1, 2026 | Sale(10b5-1 plan) | −16,667 | $6.06 | $101.00K | 1,176,506 |
| Beth Hecht See Remarks | May 1, 2026 | Sale(10b5-1 plan) | −16,667 | $6.23 | $103.84K | 1,193,173 |
| Beth Hecht See Remarks | Apr 1, 2026 | Sale(10b5-1 plan) | −16,667 | $5.99 | $99.84K | 1,209,840 |
| James Aloysius Brady Director | Mar 30, 2026 | Sale(10b5-1 plan) | −10,834 | $5.54 | $60.02K | 89,166 |
| Kevin McCulloch See Remarks | Mar 12, 2026 | Option exercise | +4 | $3.94 | $16 | 1,777,725 |
| Kevin McCulloch See Remarks | Mar 12, 2026 | Option exercise | +48,894 | $4.09 | $199.98K | 1,777,721 |
| Steven Pieper See Remarks | Mar 5, 2026 | Option exercise | +27,891 | $4.09 | $114.07K | 1,394,904 |
| Steven Pieper See Remarks | Mar 5, 2026 | Option exercise | +14,036 | $5.93 | $83.23K | 1,408,940 |
| Beth Hecht See Remarks | Mar 2, 2026 | Sale(10b5-1 plan) | −100 | $7.06 | $706 | 1,226,507 |
| Beth Hecht See Remarks | Mar 2, 2026 | Sale(10b5-1 plan) | −16,567 | $6.24 | $103.38K | 1,226,607 |
| Anh Tu Nguyen See Remarks | Feb 24, 2026 | Tax withholding | −29,300 | $6.88 | $201.58K | 395,023 |
| Beth Hecht See Remarks | Feb 2, 2026 | Sale(10b5-1 plan) | −16,667 | $7.45 | $124.17K | 1,243,174 |
| John Patrick Shannon Jr See Remarks, Director | Jan 31, 2026 | Tax withholding | −118,134 | $7.36 | $869.47K | 3,157,949 |
| John Patrick Shannon Jr See Remarks, Director | Jan 31, 2026 | Tax withholding | −111,621 | $7.36 | $821.53K | 3,046,328 |
| John Patrick Shannon Jr See Remarks, Director | Jan 31, 2026 | Tax withholding | −110,750 | $7.36 | $815.12K | 2,935,578 |
| Beth Hecht See Remarks | Jan 31, 2026 | Tax withholding | −98,375 | $7.36 | $724.04K | 1,331,021 |
| Beth Hecht See Remarks | Jan 31, 2026 | Tax withholding | −24,266 | $7.36 | $178.60K | 1,259,841 |
| Beth Hecht See Remarks | Jan 31, 2026 | Tax withholding | −46,914 | $7.36 | $345.29K | 1,284,107 |
| Kevin McCulloch See Remarks | Jan 31, 2026 | Tax withholding | −27,319 | $7.36 | $201.07K | 1,727,827 |
| Kevin McCulloch See Remarks | Jan 31, 2026 | Tax withholding | −68,454 | $7.36 | $503.82K | 1,785,435 |
| Kevin McCulloch See Remarks | Jan 31, 2026 | Tax withholding | −30,289 | $7.36 | $222.93K | 1,755,146 |
| Steven Pieper See Remarks | Jan 31, 2026 | Tax withholding | −111,765 | $7.36 | $822.59K | 1,460,782 |
| Steven Pieper See Remarks | Jan 31, 2026 | Tax withholding | −66,450 | $7.36 | $489.07K | 1,394,332 |
| Steven Pieper See Remarks | Jan 31, 2026 | Tax withholding | −27,319 | $7.36 | $201.07K | 1,367,013 |
| Anh Tu Nguyen See Remarks | Jan 30, 2026 | Award | +121,293 | – | – | 424,323 |
| John Patrick Shannon Jr See Remarks, Director | Jan 30, 2026 | Award | +478,436 | – | – | 3,276,083 |
| Beth Hecht See Remarks | Jan 30, 2026 | Award | +121,293 | – | – | 1,429,396 |
| Kevin McCulloch See Remarks | Jan 30, 2026 | Award | +168,463 | – | – | 1,853,889 |
| Steven Pieper See Remarks | Jan 30, 2026 | Award | +154,986 | – | – | 1,572,547 |
| Kevin McCulloch See Remarks | Jan 8, 2026 | Sale(10b5-1 plan) | −15,000 | $8.00 | $120.00K | 1,685,426 |
| John Patrick Shannon Jr See Remarks, Director | Jan 5, 2026 | Option exercise | +64,265 | $1.55 | $99.61K | 2,769,611 |
| John Patrick Shannon Jr See Remarks, Director | Jan 5, 2026 | Option exercise | +25,136 | $1.55 | $38.96K | 2,794,747 |
| John Patrick Shannon Jr See Remarks, Director | Jan 5, 2026 | Option exercise | +2,900 | $3.94 | $11.43K | 2,797,647 |
| John Patrick Shannon Jr See Remarks, Director | Jan 5, 2026 | Sale(10b5-1 plan) | −24,907 | $7.08 | $176.34K | 2,705,346 |
| Beth Hecht See Remarks | Jan 2, 2026 | Sale(10b5-1 plan) | −16,667 | $7.43 | $123.84K | 1,308,103 |
| John Johnson Director | Dec 19, 2025 | Sale | −135,400 | $7.22 | $977.59K | 698,083 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.
Planned insider sales
Notices of proposed sale filed on Form 144 before shares are sold
| Seller | Filed | Shares | Market value | Planned sale | Acquired through |
|---|---|---|---|---|---|
| Hecht Beth Officer | Oct 1, 2026 | 16,666 | $159.33K | Oct 1, 2026 | Restricted Stock Units |
| McCulloch Kevin Officer | Sep 28, 2026 | 70,000 | $637.00K | Sep 28, 2026 | Restricted Stock Units |
| Pieper Steven Officer | Aug 12, 2026 | 20,000 | $167.80K | Aug 12, 2026 | Restricted Stock Units |
| Pieper Steven Officer | Jul 7, 2026 | 27,600 | $231.01K | Jul 7, 2026 | Open Market Purchase |
| Pieper Steven Officer | Jul 6, 2026 | 17,400 | $144.07K | Jul 6, 2026 | Open Market Purchase |
| McCulloch Kevin Officer | Jul 1, 2026 | 120,000 | $950.40K | Jul 1, 2026 | Restricted Stock Units |
| Hecht Beth Officer | Jul 1, 2026 | 49,998 | $395.98K | Jul 1, 2026 | Restricted Stock Units |
| H. Johnson John Director | Jun 4, 2026 | 15,000 | $88.35K | Jun 4, 2026 | Restricted Stock Units |
| Bormann-Kennedy Barbara-Jean Director | Jun 4, 2026 | 16,000 | $94.24K | Jun 4, 2026 | Restricted Stock Units |
| Halkuff Dawn Director | Jun 4, 2026 | 20,000 | $117.80K | Jun 4, 2026 | Restricted Stock Units |
| Persky Marla Director | Jun 3, 2026 | 15,500 | $93.00K | Jun 3, 2026 | Restricted Stock Units |
| Brady James Director | Mar 30, 2026 | 10,834 | $58.50K | Mar 30, 2026 | Restricted Stock Units |
| Hecht Beth Officer | Mar 2, 2026 | 66,668 | $408.01K | Mar 2, 2026 | Restricted Stock Units |
| McCulloch Kevin Officer | Jan 8, 2026 | 60,000 | $432.60K | Jan 8, 2026 | Restricted Stock Units |
| H. Johnson John Director | Dec 19, 2025 | 135,402 | $977.03K | Dec 19, 2025 | Restricted Stock |