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SPRYNasdaqPharmaceutical PreparationsFiscal year ends December 31

ARS Pharmaceuticals, Inc.

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 13, 2026
$4.23+0.21 (+5.22%)

Close on Oct 19, 2026

Market cap
$420.09M
P/E (TTM)
–
Dividend yield
–

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
91.2%
91M of 99M shares
Institutional holders
206
38 new, 31 sold out
Net institutional buying
-3M
In Q2 2026
Insider trades, 12 months
0 buys · 5 sales
Net sold $1.95M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Rubric Capital Management LP8,000,0008.06%13G (passive) amendmentMar 31, 2026
James E. Flynn7,610,2177.75%13D (active) amendmentJul 30, 2025
Israel A. Englander5,916,0306.00%13G (passive) amendmentMar 27, 2026
The Pratik Shah Living Trust dated June 15, 2011(1)5,219,1245.40%13D (active) amendmentJun 13, 2024
BlackRock, Inc.5,218,2645.30%13G (passive)Jun 30, 2026
Rajeev Shah10,940,97711.10%13D (active) amendmentSep 29, 2025
Deerfield Management Company, L.P.10,514,65710.72%13D (active) amendmentMar 20, 2025

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of SPRYValueChange% of portfolio
Ra Capital Management, L.P.10,860,97710.92%$87.00M–0.76%
Rubric Capital Management LP8,540,8618.59%$68.41M+540,8610.63%
Orbimed Advisors LLC8,288,5108.33%$66.39M–1.23%
Deerfield Management Company, L.P. (Series C)7,503,8127.55%$60.11M–0.63%
BlackRock, Inc.5,311,3195.34%$42.54M+299,0650.00%
Tyro Capital Management LLC4,459,3374.48%$35.72M+1,490,7388.01%
abrdn plc4,170,6294.19%$33.41M+57,0120.05%
Sr One Capital Management, LP4,012,9034.04%$32.14M–3.09%
State Street Corp3,730,6233.75%$29.88M+85,6570.00%
Capital World Investors2,754,9312.77%$22.07MNew0.00%
Vanguard Capital Management LLC2,553,5282.57%$20.45M+11,0240.00%
Millennium Management LLC2,400,9372.41%$19.23M−3,581,9820.01%
Janney Montgomery Scott LLC2,064,4982.08%$16.54K+48,0340.03%
UBS Group AG1,939,6541.95%$15.54M−320,6710.00%
Geode Capital Management, LLC1,699,0171.71%$13.61M+172,1930.00%
Boothbay Fund Management, LLC1,601,5041.61%$12.83M+1,350,9070.17%
General American Investors Co Inc1,133,0461.14%$9.08M+405,8920.54%
Third Point LLC1,000,0001.01%$8.01M–0.17%
Peregrine Capital Management LLC672,1390.68%$5.38MNew0.17%
Tejara Capital Ltd607,0390.61%$4.86M+396,6392.00%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 202620691M91.2%38 / 7456 / 3111M15M
Q1 202620394M94.6%40 / 6157 / 2517M9M
Q4 202519190M90.7%38 / 5855 / 3317M11M
Q3 202518884M84.1%43 / 6944 / 4218M19M
Q2 202518785M85.1%28 / 8147 / 2214M6M
Q1 202518376M76.7%41 / 5953 / 2111M5M
Q4 202416571M71.7%37 / 6142 / 1913M5M
Q3 202415164M64.4%50 / 5723 / 1213M7M
Q2 202411563M63.0%24 / 4525 / 214M1M
Q1 202411360M60.5%27 / 3726 / 147M14M
Q4 202310067M67.5%19 / 3029 / 164M4M
Q3 20239767M66.9%23 / 3822 / 1820M9M

Top mutual fund and ETF holders

Latest monthly portfolio reports (Form N-PORT)

FundShares% of SPRYValue% of fundAs of
SMALLCAP World Fund Inc2,682,1882.70%$21.48M0.02%Jun 30, 2026
State Street(R) SPDR(R) S&P(R) Biotech ETF2,287,0412.30%$18.32M0.17%Jun 30, 2026
Vanguard Total Stock Market Index Fund1,749,7631.76%$14.02M0.00%Jun 30, 2026
iShares Russell 2000 ETF1,608,6671.62%$12.89M0.02%Jun 30, 2026
Vanguard Extended Market Index Fund746,0630.75%$5.98M0.01%Jun 30, 2026
Fidelity Small Cap Index Fund670,4630.67%$3.44M0.01%Jul 31, 2026
iShares Russell 2000 Growth ETF578,4260.58%$4.63M0.03%Jun 30, 2026
iShares Biotechnology ETF442,1150.44%$3.54M0.04%Jun 30, 2026
Fidelity Extended Market Index Fund339,0300.34%$3.08M0.01%May 31, 2026
Select Biotechnology Portfolio335,1560.34%$3.04M0.06%May 31, 2026
Schwab U.S. Small-Cap ETF310,9980.31%$2.82M0.01%May 31, 2026
Vanguard Russell 2000 Index Fund303,5400.31%$2.75M0.02%May 31, 2026
Optimum Small-Mid Cap Growth Fund219,6960.22%$1.76M0.19%Jun 30, 2026
Vanguard Health Care Index Fund162,0480.16%$1.47M0.01%May 31, 2026
Schwab Small-Cap Index Fund149,8130.15%$768.54K0.01%Jul 31, 2026

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
Richard E. LowenthalPRESIDENT AND CEO, Director, 10% owner15,630,33015.72%Jan 5, 2026
Margaret Ekins SmithChief Commercial Officer––Sep 2, 2026
Donn CasalePresident––Jul 2, 2026
Alexander A. FitzpatrickChief Legal Officer90,9100.09%Jun 12, 2026
Eric KarasChief Commercial Officer12,1760.01%Jun 12, 2026
Brian DorseyChief Operating Officer10,7890.01%Jan 5, 2026
Justin ChakmaChief Business Officer166,3800.17%Jan 5, 2026
Kathleen D. ScottChief Financial Officer18,2920.02%Jan 5, 2026
Sarina TanimotoCHIEF MEDICAL OFFICER, 10% owner14,786,65314.87%Jan 5, 2026
Pratik ShahDirector4,574,5544.60%Jun 26, 2026
Capital Healthcare Fund LP RADirector, 10% owner8,365,4658.41%Jun 26, 2026
Rajeev M. ShahDirector, 10% owner902,9040.91%Jun 26, 2026
Peter KolchinskyDirector, 10% owner––Jun 26, 2026
Ra Capital Management, L.P.Director, 10% owner9,958,07310.01%Jun 26, 2026
RA Capital Nexus Fund II, L.P.Director––Jun 26, 2026
Peter A. ThompsonDirector0–Jun 26, 2026
Brent L. SaundersDirector0–Jun 26, 2026
Saqib IslamDirector15,2390.02%Jun 26, 2026
Laura ShawverDirector210,3460.21%Jun 26, 2026
Rajeev DadooDirector3,009,6773.03%Jun 26, 2026
Michael KellyDirector83,2250.08%Jun 26, 2026
Phillip M. SchneiderDirector––Jun 26, 2026
Deerfield Private Design Fund III, L.P.10% owner10,524,21010.58%Jul 1, 2025
Deerfield Mgmt III, L.P.10% owner––Jul 1, 2025
Deerfield Management Company, L.P.10% owner––Jul 1, 2025
Deerfield Private Design Fund IV, L.P.10% owner––Jul 1, 2025
Deerfield Mgmt IV, L.P.10% owner––Jul 1, 2025
James E. Flynn10% owner20,852,43620.97%Jul 1, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
Alexander A. Fitzpatrick
Chief Legal Officer
Jun 12, 2026Sale(10b5-1 plan)−3,355$10.00$33.55K90,910
Eric Karas
Chief Commercial Officer
Jun 12, 2026Sale(10b5-1 plan)−25,000$10.00$250.00K12,176
Eric Karas
Chief Commercial Officer
Jun 12, 2026Option exercise+25,000$1.50$37.50K37,176
Brian Dorsey
Chief Operating Officer
Nov 13, 2025Sale−21,828$8.71$190.12K10,789
Brian Dorsey
Chief Operating Officer
Nov 13, 2025Option exercise+21,828$0.64$13.97K32,617
Justin Chakma
Chief Business Officer
Nov 12, 2025Option exercise+30,000$0.84$25.20K166,380
Justin Chakma
Chief Business Officer
Nov 12, 2025Sale−30,000$8.91$267.30K136,380
Justin Chakma
Chief Business Officer
Nov 12, 2025Sale−136,380$8.86$1.21M0
Pratik Shah
Director
Nov 12, 2025Gift−250,000––4,574,554
Pratik Shah
Director
Nov 12, 2025Gift−100,000––4,474,554
Richard E. Lowenthal
PRESIDENT AND CEO, Director, 10% owner
Aug 21, 2025Sale(10b5-1 plan)−50,000$14.49$724.50K1,196,494
Kathleen D. Scott
Chief Financial Officer
Aug 21, 2025Sale(10b5-1 plan)−12,500$15.00$187.50K10,042
Kathleen D. Scott
Chief Financial Officer
Aug 21, 2025Option exercise+12,500$1.50$18.75K22,542
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Aug 20, 2025Sale(10b5-1 plan)−37,656$14.09$530.57K1,247,447
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Aug 19, 2025Sale(10b5-1 plan)−12,344$14.03$173.19K1,285,103
Eric Karas
Chief Commercial Officer
Jul 1, 2025Sale(10b5-1 plan)−15,000$16.99$254.85K10,315
Eric Karas
Chief Commercial Officer
Jul 1, 2025Option exercise+15,000$1.50$22.50K25,315
James E. Flynn
10% owner
Jun 27, 2025Sale−370,075$18.46$6.83M4,887,254
James E. Flynn
10% owner
Jun 27, 2025Sale−370,074$18.46$6.83M4,887,254
Eric Karas
Chief Commercial Officer
Jun 18, 2025Option exercise+15,000$1.50$22.50K22,696
Eric Karas
Chief Commercial Officer
Jun 18, 2025Sale(10b5-1 plan)−15,000$16.00$240.00K7,696
Kathleen D. Scott
Chief Financial Officer
May 20, 2025Sale−50,000$14.10$705.00K7,424
Kathleen D. Scott
Chief Financial Officer
May 20, 2025Option exercise+50,000$1.50$75.00K57,424
Brent L. Saunders
Director
May 20, 2025Sale−120,000$14.25$1.71M0
Brent L. Saunders
Director
May 20, 2025Option exercise+120,000$1.01$121.20K120,000
Alexander A. Fitzpatrick
Chief Legal Officer
May 20, 2025Sale−102,969$14.10$1.45M89,613
Alexander A. Fitzpatrick
Chief Legal Officer
May 20, 2025Option exercise+100,000$5.58$558.00K192,582
Laura Shawver
Director
Apr 7, 2025Sale(10b5-1 plan)−50,002$12.30$615.02K210,346
Laura Shawver
Director
Apr 7, 2025Option exercise+27,493$4.85$133.34K260,348
Laura Shawver
Director
Apr 7, 2025Option exercise+22,509$4.85$109.17K232,855
Eric Karas
Chief Commercial Officer
Mar 20, 2025Sale(10b5-1 plan)−10,000$14.00$140.00K7,696
Eric Karas
Chief Commercial Officer
Mar 20, 2025Option exercise+10,000$1.50$15.00K17,696
Laura Shawver
Director
Mar 6, 2025Option exercise+49,600$4.85$240.56K259,946
Laura Shawver
Director
Mar 6, 2025Sale(10b5-1 plan)−49,600$11.21$556.02K210,346
Laura Shawver
Director
Mar 5, 2025Sale(10b5-1 plan)−400$11.00$4.40K210,346
Laura Shawver
Director
Mar 5, 2025Option exercise+400$4.85$1.94K210,746
Laura Shawver
Director
Feb 3, 2025Option exercise+9,064$3.15$28.55K219,410
Laura Shawver
Director
Feb 3, 2025Sale(10b5-1 plan)−50,000$12.31$615.50K210,346
Laura Shawver
Director
Feb 3, 2025Option exercise+40,936$4.85$198.54K260,346
Laura Shawver
Director
Jan 6, 2025Sale(10b5-1 plan)−50,000$11.10$555.00K210,346
Laura Shawver
Director
Jan 6, 2025Option exercise+50,000$3.15$157.50K260,346
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Dec 17, 2024Sale(10b5-1 plan)−50,000$11.67$583.50K1,098,499
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Dec 17, 2024Sale(10b5-1 plan)−50,000$11.67$583.50K1,297,447
Richard E. Lowenthal
PRESIDENT AND CEO, Director, 10% owner
Dec 17, 2024Sale(10b5-1 plan)−50,000$11.67$583.50K1,297,447
Richard E. Lowenthal
PRESIDENT AND CEO, Director, 10% owner
Dec 17, 2024Sale(10b5-1 plan)−50,000$11.67$583.50K1,098,499
Justin Chakma
Chief Business Officer
Dec 13, 2024Option exercise+27,272$1.44$39.27K163,652
Justin Chakma
Chief Business Officer
Dec 13, 2024Sale−27,272$12.06$328.90K136,380
Brian Dorsey
Chief Operating Officer
Dec 12, 2024Sale(10b5-1 plan)−25,000$12.30$307.50K6,024
Brian Dorsey
Chief Operating Officer
Dec 12, 2024Option exercise+25,000$0.64$16.00K31,024
Justin Chakma
Chief Business Officer
Dec 12, 2024Sale−117,333$12.27$1.44M136,380
Justin Chakma
Chief Business Officer
Dec 12, 2024Option exercise+117,333$0.84$98.56K253,713
Brian Dorsey
Chief Operating Officer
Dec 11, 2024Sale(10b5-1 plan)−15,000$12.43$186.45K6,024
Brian Dorsey
Chief Operating Officer
Dec 11, 2024Option exercise+15,000$0.64$9.60K21,024
Justin Chakma
Chief Business Officer
Dec 10, 2024Sale−50,000$13.15$657.50K136,380
Justin Chakma
Chief Business Officer
Dec 10, 2024Option exercise+50,000$0.84$42.00K186,380
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Dec 10, 2024Sale(10b5-1 plan)−50,000$13.16$658.00K1,148,499
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Dec 10, 2024Sale(10b5-1 plan)−50,000$13.17$658.50K1,246,494
Richard E. Lowenthal
PRESIDENT AND CEO, Director, 10% owner
Dec 10, 2024Sale(10b5-1 plan)−50,000$13.17$658.50K1,246,494
Richard E. Lowenthal
PRESIDENT AND CEO, Director, 10% owner
Dec 10, 2024Sale(10b5-1 plan)−50,000$13.16$658.00K1,148,499
Sarina Tanimoto
CHIEF MEDICAL OFFICER, 10% owner
Dec 6, 2024Option exercise+11,876$8.42$100.00K3,433,512

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
Karas Eric
Officer
Oct 1, 2026100,000$426.10KOct 1, 2026Stock Option Exercise
Karas Eric
Officer
Sep 30, 2026100,000$431.56KSep 30, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Sep 11, 202635,000$177.00KSep 11, 2026Stock Option Exercise
Karas Eric
Officer
Sep 11, 202614,064$69.76KSep 11, 2026Employee Stock Purchase Plan
Lowenthal Richard
Officer, Director, 10% Stockholder
Sep 4, 202675,000$421.06KSep 4, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Sep 3, 202619,805$115.56KSep 3, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Sep 2, 2026840$5.00KSep 2, 2026Stock Option Exercise
Tanimoto Sarina
Officer, 10% Stockholder
Sep 1, 202645,388$272.85KSep 1, 2026Stock Option Exercise
Tanimoto Sarina
Officer, 10% Stockholder
Aug 31, 202663,289$368.10KAug 31, 2026Stock Option Exercise
Tanimoto Sarina
Officer, 10% Stockholder
Aug 20, 202625,000$147.97KAug 20, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Aug 20, 202625,000$148.16KAug 20, 2026Stock Option Exercise
Tanimoto Sarina
Officer, 10% Stockholder
Aug 19, 202625,000$161.17KAug 19, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Aug 19, 202650,000$322.35KAug 19, 2026Stock Option Exercise
Tanimoto Sarina
Officer, 10% Stockholder
Aug 18, 202649,401$311.19KAug 18, 2026Stock Option Exercise
Lowenthal Richard
Officer, Director, 10% Stockholder
Aug 18, 202650,000$315.89KAug 18, 2026Stock Option Exercise