OBIONasdaqSurgical & Medical Instruments & ApparatusFiscal year ends December 31
Orchestra BioMed Holdings, Inc.
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 10, 2026
$5.65+0.20 (+3.67%)
Close on Oct 19, 2026
- Market cap
- $360.54M
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
46.1%
28M of 60M shares
Institutional holders
77
25 new, 13 sold out
Net institutional buying
5M
In Q2 2026
Insider trades, 12 months
9 buys · 5 sales
Net bought $22.21K
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| Roderick Wong, M.D. | 8,306,063 | 21.70% | 13D (active) amendment | Apr 29, 2025 |
| RTW Investments, LP | 8,306,063 | 15.40% | 13D (active) amendment | Aug 4, 2025 |
| Medtronic plc | 5,868,916 | 15.40% | 13G (passive) amendment | Dec 31, 2024 |
| Joseph Edelman | 5,679,480 | 9.99% | 13G (passive) amendment | Sep 30, 2025 |
| Dana Lorenzo | 3,098,592 | 5.50% | 13G (passive) | Nov 15, 2025 |
| Roderick Wong | 11,942,394 | 19.20% | 13D (active) amendment | Apr 27, 2026 |
| Covidien Group S.a.r.l. | 10,078,625 | 17.80% | 13G (passive) amendment | Dec 31, 2025 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of OBIO | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| Rtw Investments, LP | 9,556,063 | 15.90% | $41.23M | +1,250,000 | 0.35% |
| Perceptive Advisors LLC | 5,037,906 | 8.38% | $21.74M | – | 0.33% |
| BlackRock, Inc. | 2,510,387 | 4.18% | $10.83M | +1,874,673 | 0.00% |
| Vanguard Capital Management LLC | 2,022,916 | 3.37% | $8.73M | −181,403 | 0.00% |
| Geode Capital Management, LLC | 1,007,908 | 1.68% | $4.35M | +522,416 | 0.00% |
| Alyeska Investment Group, L.P. | 1,000,000 | 1.66% | $4.32M | – | 0.01% |
| Propel Bio Management, LLC | 896,701 | 1.49% | $3.87M | – | 2.02% |
| UBS Asset Management Americas Inc | 642,154 | 1.07% | $2.77M | New | 0.00% |
| State Street Corp | 516,050 | 0.86% | $2.23M | +346,640 | 0.00% |
| Rice Hall James & Associates, LLC | 424,000 | 0.71% | $1.83M | +404,999 | 0.09% |
| Charles Schwab Investment Management Inc | 349,544 | 0.58% | $1.51M | +84,045 | 0.00% |
| Northern Trust Corp | 343,640 | 0.57% | $1.48M | +225,366 | 0.00% |
| UBS Group AG | 325,773 | 0.54% | $1.41M | +275,463 | 0.00% |
| Vanguard Fiduciary Trust Co | 292,253 | 0.49% | $1.26M | +57,039 | 0.00% |
| Vanguard Portfolio Management LLC | 274,973 | 0.46% | $1.19M | New | 0.00% |
| Knott David M Jr | 253,651 | 0.42% | $1.09M | – | 0.58% |
| Flat Footed LLC | 251,372 | 0.42% | $1.08M | New | 0.08% |
| Simplify Asset Management Inc. | 219,387 | 0.37% | $946.66K | – | 0.01% |
| Goldman Sachs Group Inc | 179,606 | 0.30% | $775.00K | +24,364 | 0.00% |
| DAFNA Capital Management LLC | 126,841 | 0.21% | $547.32K | – | 0.10% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 77 | 28M | 46.1% | 25 / 22 | 15 / 13 | 7M | 2M |
| Q1 2026 | 65 | 23M | 38.4% | 19 / 23 | 14 / 16 | 5M | 2M |
| Q4 2025 | 63 | 22M | 36.1% | 21 / 17 | 14 / 5 | 2M | 3M |
| Q3 2025 | 52 | 23M | 38.1% | 10 / 16 | 17 / 17 | 5M | 1M |
| Q2 2025 | 59 | 18M | 30.2% | 22 / 14 | 16 / 19 | 2M | 3M |
| Q1 2025 | 56 | 19M | 31.6% | 7 / 16 | 18 / 4 | 0M | 0M |
| Q4 2024 | 54 | 19M | 32.0% | 10 / 26 | 7 / 4 | 1M | 0M |
| Q3 2024 | 48 | 19M | 31.7% | 7 / 20 | 10 / 5 | 7M | 0M |
| Q2 2024 | 47 | 14M | 23.7% | 8 / 22 | 8 / 4 | 1M | 0M |
| Q1 2024 | 43 | 13M | 22.3% | 5 / 14 | 16 / 1 | 0M | 0M |
| Q4 2023 | 39 | 13M | 22.1% | 2 / 19 | 7 / 5 | 0M | 0M |
| Q3 2023 | 42 | 13M | 21.8% | 8 / 23 | 6 / 5 | 3M | 0M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of OBIO | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 1,470,063 | 2.45% | $6.34M | 0.00% | Jun 30, 2026 |
| iShares Russell 2000 ETF | 830,752 | 1.38% | $3.58M | 0.00% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 498,632 | 0.83% | $2.15M | 0.00% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund | 428,758 | 0.71% | $1.71M | 0.01% | Jul 31, 2026 |
| iShares Russell 2000 Growth ETF | 374,286 | 0.62% | $1.62M | 0.01% | Jun 30, 2026 |
| Simplify Propel Opportunities ETF | 219,387 | 0.37% | $946.65K | 1.23% | Jun 30, 2026 |
| BlackRock Health Sciences Opportunities Portfolio | 206,130 | 0.34% | $805.97K | 0.01% | May 29, 2026 |
| Fidelity Extended Market Index Fund | 205,715 | 0.34% | $804.35K | 0.00% | May 31, 2026 |
| Schwab U.S. Small-Cap ETF | 178,322 | 0.30% | $697.24K | 0.00% | May 31, 2026 |
| iShares Micro-Cap ETF | 133,768 | 0.22% | $577.21K | 0.04% | Jun 30, 2026 |
| Schwab Small-Cap Index Fund | 97,254 | 0.16% | $387.07K | 0.01% | Jul 31, 2026 |
| Clearwater Select Equity Fund | 86,424 | 0.14% | $372.92K | 0.07% | Jun 30, 2026 |
| Master Small Cap Index Series | 74,501 | 0.12% | $321.47K | 0.01% | Jun 30, 2026 |
| Ultra-Small Company Market Fund | 73,500 | 0.12% | $317.15K | 0.21% | Jun 30, 2026 |
| Fidelity Total Market Index Fund | 72,838 | 0.12% | $284.80K | 0.00% | May 31, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| David P. Hochman | See Remarks, Director | 1,509,519 | 2.51% | Sep 11, 2026 |
| Darren Sherman | See Remarks, Director | 1,136,402 | 1.89% | Sep 2, 2026 |
| Andrew Lawrence Taylor | Chief Financial Officer | 589,989 | 0.98% | Aug 28, 2026 |
| Joshua Aiello | Principal Accounting Officer | 18,441 | 0.03% | Aug 28, 2026 |
| Chris Cleary | Director | 29,153 | 0.05% | Aug 14, 2026 |
| John Prosper Mack | Director | 66,544 | 0.11% | Aug 14, 2026 |
| David Pacitti | Director | 54,750 | 0.09% | Aug 14, 2026 |
| Eric S. Fain | Director | 107,130 | 0.18% | Aug 14, 2026 |
| Jason Aryeh | Director | 118,118 | 0.20% | Jun 25, 2026 |
| Pamela Ann Connealy | Director | 66,038 | 0.11% | Jun 25, 2026 |
| Rtw Investments, Lp | 10% owner | 9,556,063 | 15.90% | Apr 29, 2026 |
| Roderick Wong | 10% owner | 8,306,063 | 13.82% | Apr 29, 2026 |
| Joseph Edelman | 10% owner | – | – | Aug 5, 2025 |
| Life Sciences Master Fund Ltd Perceptive | 10% owner | 5,292,556 | 8.81% | Aug 5, 2025 |
| Advisors Llc Perceptive | 10% owner | – | – | Aug 5, 2025 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| David P. Hochman See Remarks, Director | Sep 10, 2026 | Tax withholding | −3,283 | $5.81 | $19.07K | 1,067,463 |
| David P. Hochman See Remarks, Director | Sep 10, 2026 | Tax withholding | −3,283 | $5.81 | $19.07K | 432,916 |
| David P. Hochman See Remarks, Director | Sep 3, 2026 | Buy | +10,000 | $4.79 | $47.90K | 1,070,746 |
| Darren Sherman See Remarks, Director | Sep 1, 2026 | Sale(10b5-1 plan) | −15,000 | $4.94 | $74.10K | 1,134,402 |
| Joshua Aiello Principal Accounting Officer | Aug 26, 2026 | Tax withholding | −203 | $5.26 | $1.07K | 18,441 |
| Andrew Lawrence Taylor Chief Financial Officer | Aug 26, 2026 | Tax withholding | −3,076 | $5.26 | $16.18K | 589,989 |
| Darren Sherman See Remarks, Director | Aug 26, 2026 | Buy | +2,000 | $5.33 | $10.66K | 2,000 |
| Darren Sherman See Remarks, Director | Aug 26, 2026 | Tax withholding | −4,925 | $5.26 | $25.91K | 1,149,402 |
| John Prosper Mack Director | Aug 12, 2026 | Tax withholding | −4,885 | $4.42 | $21.59K | 66,544 |
| Eric S. Fain Director | Aug 12, 2026 | Tax withholding | −5,145 | $4.42 | $22.74K | 99,630 |
| Chris Cleary Director | Aug 12, 2026 | Tax withholding | −4,238 | $4.42 | $18.73K | 29,153 |
| David Pacitti Director | Aug 12, 2026 | Tax withholding | −3,761 | $4.42 | $16.62K | 54,750 |
| Darren Sherman See Remarks, Director | Aug 3, 2026 | Sale(10b5-1 plan) | −15,000 | $4.09 | $61.35K | 1,154,327 |
| Darren Sherman See Remarks, Director | Jul 1, 2026 | Sale(10b5-1 plan) | −15,000 | $4.27 | $64.05K | 1,169,327 |
| John Prosper Mack Director | Jun 24, 2026 | Tax withholding | −3,510 | – | – | 71,429 |
| David Pacitti Director | Jun 24, 2026 | Tax withholding | −3,784 | – | – | 58,511 |
| Eric S. Fain Director | Jun 24, 2026 | Tax withholding | −4,261 | – | – | 104,775 |
| Chris Cleary Director | Jun 24, 2026 | Tax withholding | −3,510 | – | – | 33,391 |
| John Prosper Mack Director | Jun 23, 2026 | Award | +34,653 | – | – | 74,939 |
| David Pacitti Director | Jun 23, 2026 | Award | +17,327 | – | – | 62,295 |
| Eric S. Fain Director | Jun 23, 2026 | Award | +17,327 | – | – | 109,036 |
| Pamela Ann Connealy Director | Jun 23, 2026 | Award | +17,327 | – | – | 66,038 |
| Andrew Lawrence Taylor Chief Financial Officer | Jun 10, 2026 | Tax withholding | −36,352 | $4.02 | $146.14K | 593,065 |
| David P. Hochman See Remarks, Director | Jun 10, 2026 | Tax withholding | −3,283 | $4.02 | $13.20K | 1,060,746 |
| David P. Hochman See Remarks, Director | Jun 10, 2026 | Tax withholding | −3,283 | $4.02 | $13.20K | 436,199 |
| Darren Sherman See Remarks, Director | Jun 1, 2026 | Sale(10b5-1 plan) | −15,000 | $3.87 | $58.05K | 1,184,327 |
| David P. Hochman See Remarks, Director | Jun 1, 2026 | Buy | +5,000 | $3.83 | $19.15K | 1,064,029 |
| Andrew Lawrence Taylor Chief Financial Officer | May 28, 2026 | Tax withholding | −3,076 | $3.98 | $12.24K | 629,417 |
| Darren Sherman See Remarks, Director | May 28, 2026 | Tax withholding | −4,925 | $3.98 | $19.60K | 1,199,327 |
| Jason Aryeh Director | May 18, 2026 | Buy | +665 | $3.75 | $2.49K | 118,118 |
| David P. Hochman See Remarks, Director | May 15, 2026 | Buy | +5,000 | $3.77 | $18.85K | 1,059,029 |
| Jason Aryeh Director | May 15, 2026 | Buy | +8,971 | $3.90 | $34.99K | 117,453 |
| Eric S. Fain Director | May 14, 2026 | Buy | +20,000 | $4.13 | $82.60K | 91,709 |
| Rtw Investments, Lp 10% owner | Apr 27, 2026 | Sale | −32 | $4.13 | $132 | 9,556,063 |
| Rtw Investments, Lp 10% owner | Apr 27, 2026 | Option exercise | +1,250,032 | – | – | 9,556,095 |
| Darren Sherman See Remarks, Director | Mar 25, 2026 | Tax withholding | −33,317 | $4.57 | $152.26K | 1,204,252 |
| Joshua Aiello Principal Accounting Officer | Mar 25, 2026 | Tax withholding | −241 | $4.57 | $1.10K | 18,644 |
| David P. Hochman See Remarks, Director | Mar 25, 2026 | Tax withholding | −32,438 | $4.57 | $148.24K | 1,054,029 |
| David P. Hochman See Remarks, Director | Mar 13, 2026 | Buy | +10,000 | $4.29 | $42.90K | 1,086,467 |
| Andrew Lawrence Taylor Chief Financial Officer | Feb 12, 2026 | Award | +181,000 | – | – | 632,493 |
| David P. Hochman See Remarks, Director | Feb 12, 2026 | Award | +504,000 | – | – | 1,076,467 |
| Darren Sherman See Remarks, Director | Feb 12, 2026 | Award | +397,000 | – | – | 1,237,569 |
| Chris Cleary Director | Feb 5, 2026 | Tax withholding | −676 | $3.71 | $2.51K | 36,901 |
| Darren Sherman See Remarks, Director | Jan 2, 2026 | Tax withholding | −5,588 | $4.31 | $24.08K | 840,569 |
| Andrew Lawrence Taylor Chief Financial Officer | Jan 2, 2026 | Tax withholding | −3,452 | $4.31 | $14.88K | 451,493 |
| Joshua Aiello Principal Accounting Officer | Jan 2, 2026 | Tax withholding | −241 | $4.31 | $1.04K | 18,885 |
| Andrew Lawrence Taylor Chief Financial Officer | Dec 10, 2025 | Tax withholding | −8,670 | $4.67 | $40.49K | 454,945 |
| David P. Hochman See Remarks, Director | Dec 10, 2025 | Tax withholding | −3,283 | $4.67 | $15.33K | 439,482 |
| David P. Hochman See Remarks, Director | Dec 10, 2025 | Tax withholding | −40,355 | $4.67 | $188.46K | 572,467 |
| Andrew Lawrence Taylor Chief Financial Officer | Nov 25, 2025 | Tax withholding | −3,071 | $5.35 | $16.43K | 463,615 |
| Darren Sherman See Remarks, Director | Nov 25, 2025 | Tax withholding | −40,340 | $5.35 | $215.82K | 846,157 |
| David P. Hochman See Remarks, Director | Nov 14, 2025 | Buy | +5,000 | $4.07 | $20.35K | 612,822 |
| David P. Hochman See Remarks, Director | Nov 13, 2025 | Tax withholding | −3,283 | $4.18 | $13.72K | 607,822 |
| David P. Hochman See Remarks, Director | Nov 13, 2025 | Tax withholding | −3,283 | $4.18 | $13.72K | 442,765 |
| Jason Aryeh Director | Sep 19, 2025 | Buy | +1,000 | $2.45 | $2.45K | 108,482 |
| David P. Hochman See Remarks, Director | Sep 17, 2025 | Tax withholding | −3,283 | $2.46 | $8.08K | 446,048 |
| David P. Hochman See Remarks, Director | Sep 17, 2025 | Tax withholding | −40,355 | $2.46 | $99.27K | 611,105 |
| Joshua Aiello Principal Accounting Officer | Sep 17, 2025 | Tax withholding | −203 | $2.46 | $499 | 19,126 |
| Andrew Lawrence Taylor Chief Financial Officer | Sep 17, 2025 | Tax withholding | −16,102 | $2.46 | $39.61K | 466,686 |
| Darren Sherman See Remarks, Director | Sep 3, 2025 | Tax withholding | −40,340 | $2.72 | $109.72K | 886,497 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.
Planned insider sales
Notices of proposed sale filed on Form 144 before shares are sold
| Seller | Filed | Shares | Market value | Planned sale | Acquired through |
|---|---|---|---|---|---|
| Darren Sherman Officer, Director | Oct 1, 2026 | 15,000 | $94.05K | Oct 1, 2026 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 1, 2026 | 15,000 | $75.30K | Sep 1, 2026 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Aug 3, 2026 | 15,000 | $61.29K | Aug 3, 2026 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Jul 1, 2026 | 15,000 | $64.80K | Jul 1, 2026 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Jun 1, 2026 | 15,000 | $58.05K | Jun 1, 2026 | Restricted Stock Vesting |
| Eric S. Fain Director | Jun 26, 2025 | 2,683 | $8.19K | Jun 26, 2025 | Restricted Stock Vesting |
| Eric S. Fain Director | Sep 10, 2024 | 1,800 | $9.62K | Sep 10, 2024 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 10, 2024 | 6,904 | $36.65K | Sep 10, 2024 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 9, 2024 | 6,804 | $37.32K | Sep 9, 2024 | Restricted Stock Vesting |
| Eric S. Fain Director | Sep 9, 2024 | 1,800 | $9.77K | Sep 9, 2024 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 6, 2024 | 6,819 | $38.51K | Sep 6, 2024 | Restricted Stock Vesting |
| Eric S. Fain Director | Sep 6, 2024 | 2,000 | $11.28K | Sep 6, 2024 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 5, 2024 | 6,961 | $40.71K | Sep 5, 2024 | Restricted Stock Vesting |
| Darren Sherman Officer, Director | Sep 4, 2024 | 6,837 | $41.70K | Sep 4, 2024 | Restricted Stock Vesting |