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MISTNasdaqPharmaceutical PreparationsFiscal year ends December 31

Milestone Pharmaceuticals Inc.

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 12, 2026
$0.70−0.01 (-1.02%)

Close on Oct 19, 2026

Market cap
–
P/E (TTM)
–
Dividend yield
–

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
40.8%
51M of 124M shares
Institutional holders
78
6 new, 13 sold out
Net institutional buying
11M
In Q2 2026
Insider trades, 12 months
0 buys · 13 sales
Net sold $1.18M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Roderick Wong9,155,1689.90%13G (passive) amendmentSep 30, 2025
Pavaki Capital Management LLC9,067,8487.30%13G (passive)Dec 31, 2025
Trails Edge Biotechnology Master Fund, LP9,017,8809.90%13G (passive) amendmentSep 30, 2025
Richard Kayne8,861,1869.90%13G (passive)Jul 11, 2025
Robert Atchinson8,659,0649.99%13G (passive)Sep 30, 2025
Phillip Gross8,000,0006.37%13G (passive) amendmentMar 31, 2026
RTW Investments, LP12,356,9539.90%13G (passive) amendmentMar 31, 2026

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of MISTValueChange% of portfolio
Pavaki Capital Management LLC9,067,8487.28%$12.15M+5,0004.24%
Rtw Investments, LP7,833,3366.29%$10.50M+1,502,3350.09%
Propel Bio Management, LLC7,429,5905.97%$9.96M+3,311,2695.21%
Point72 Asset Management, L.P.5,411,1384.35%$7.25M+4,325,4550.01%
Simplify Asset Management Inc.3,349,3792.69%$4.49M+1,842,9740.06%
Millennium Management LLC3,142,2192.52%$4.21M+1,597,8940.00%
Kalehua Capital Management LLC2,538,4742.04%$3.40MNew1.09%
Two Sigma Investments, LP2,040,0151.64%$2.73M−277,1610.00%
Marshall Wace, Llp1,797,6951.44%$2.41M−146,8350.00%
Lion Point Capital, LP820,0000.66%$1.10M–5.26%
Toronto Dominion Bank750,0000.60%$1.01M–0.00%
Ameriprise Financial Inc666,6660.54%$893.33K–0.00%
Boxer Capital Management, LLC666,6660.54%$893.33K–0.07%
Morgan Stanley635,2110.51%$851.18K−88,9300.00%
UBS Group AG465,4030.37%$623.64K−29,5050.00%
Boothbay Fund Management, LLC462,6690.37%$619.98K+293,9940.01%
Susquehanna International Group, Llp359,8950.29%$482.26K−159,1510.00%
Aptus Capital Advisors, LLC339,4500.27%$454.86K+59,2000.00%
Guardian Wealth Advisors, LLC / Nc339,4500.27%$454.86K+59,2000.03%
Seven Fleet Capital Management LP270,2330.22%$362.11K−63,1000.06%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 20267851M40.8%6 / 2323 / 1316M5M
Q1 20268740M31.7%21 / 2319 / 1412M8M
Q4 20258035M28.1%29 / 219 / 916M15M
Q3 20256134M27.4%26 / 184 / 725M3M
Q2 20254312M9.5%10 / 109 / 101M1M
Q1 20254312M9.5%14 / 611 / 173M16M
Q4 20244725M19.7%10 / 1414 / 62M6M
Q3 20244329M23.0%5 / 910 / 15M4M
Q2 20244032M25.6%3 / 97 / 63M4M
Q1 20244333M26.5%11 / 137 / 716M1M
Q4 20234019M14.9%8 / 910 / 73M4M
Q3 20233920M15.7%2 / 914 / 110M2M

Top mutual fund and ETF holders

Latest monthly portfolio reports (Form N-PORT)

FundShares% of MISTValue% of fundAs of
Simplify Propel Opportunities ETF3,349,3792.69%$4.49M5.81%Jun 30, 2026
Invesco NASDAQ Future Gen 200 ETF44,9360.04%$63.81K0.34%May 31, 2026
Fidelity Nasdaq Composite Index Fund40,7890.03%$57.92K0.00%May 31, 2026
State Street(R) SPDR(R) S&P(R) International Small Cap ETF22,5640.02%$30.24K0.00%Jun 30, 2026
Blackstone Alternative Multi-Strategy Fund10,9990.01%$14.74K0.00%Jun 30, 2026

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
Joseph OlivetoPresident and CEO, Director446,2440.36%Apr 20, 2026
David I. SandovalGC & Chief Compliance Officer––Mar 23, 2026
Amit HasijaCFO & EVP of Corp. Development112,0930.09%Feb 5, 2026
Lorenz MullerChief Commercial Officer205,4060.16%Feb 5, 2026
David BharuchaChief Medical Officer125,4260.10%Feb 5, 2026
Jeffrey Edward NelsonChief Operating Officer49,8480.04%Feb 5, 2026
Stuart DutyDirector––Jun 12, 2026
Robert James WillsDirector65,0000.05%Jun 12, 2026
Joseph C. PapaDirector100,0000.08%Jun 12, 2026
Seth H. Z. FischerDirector––Jun 12, 2026
Michael John TomsicekDirector15,0000.01%Jun 12, 2026
Andrew SaikDirector––Jun 12, 2026
Lisa M. GilesDirector––Jun 12, 2026
Debra K. LiebertDirector30,7930.02%Jul 15, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
Joseph Oliveto
President and CEO, Director
Apr 16, 2026Sale(10b5-1 plan)−36,500$2.26$82.49K446,244
Joseph Oliveto
President and CEO, Director
Jan 26, 2026Option exercise+66,600––517,267
Joseph Oliveto
President and CEO, Director
Jan 26, 2026Sale−34,523$1.93$66.63K482,744
Jeffrey Edward Nelson
Chief Operating Officer
Jan 26, 2026Sale−12,245$1.93$23.63K49,848
Jeffrey Edward Nelson
Chief Operating Officer
Jan 26, 2026Option exercise+20,100––62,093
Amit Hasija
CFO & EVP of Corp. Development
Jan 26, 2026Option exercise+20,100––112,093
Amit Hasija
CFO & EVP of Corp. Development
Jan 26, 2026Sale−12,245$1.93$23.63K99,848
Lorenz Muller
Chief Commercial Officer
Jan 26, 2026Sale−11,180$1.93$21.58K205,406
Lorenz Muller
Chief Commercial Officer
Jan 26, 2026Option exercise+20,100––216,586
David Bharucha
Chief Medical Officer
Jan 26, 2026Option exercise+20,100––125,426
David Bharucha
Chief Medical Officer
Jan 26, 2026Sale−12,245$1.93$23.63K113,181
Joseph Oliveto
President and CEO, Director
Jan 8, 2026Sale(10b5-1 plan)−43,000$2.25$96.75K303,721
Joseph Oliveto
President and CEO, Director
Jan 7, 2026Sale(10b5-1 plan)−500$2.25$1.13K346,721
Joseph Oliveto
President and CEO, Director
Dec 15, 2025Sale−133,054$2.32$308.69K450,667
Jeffrey Edward Nelson
Chief Operating Officer
Dec 15, 2025Sale−58,007$2.32$134.58K41,993
Amit Hasija
CFO & EVP of Corp. Development
Dec 15, 2025Sale−58,007$2.32$134.58K91,993
Lorenz Muller
Chief Commercial Officer
Dec 15, 2025Sale−53,566$2.32$124.27K196,486
David Bharucha
Chief Medical Officer
Dec 15, 2025Sale−58,007$2.32$134.58K105,326
Joseph Oliveto
President and CEO, Director
Dec 12, 2025Award+280,000––583,721
Jeffrey Edward Nelson
Chief Operating Officer
Dec 12, 2025Award+100,000––100,000
Amit Hasija
CFO & EVP of Corp. Development
Dec 12, 2025Award+100,000––150,000
Lorenz Muller
Chief Commercial Officer
Dec 12, 2025Award+100,000––250,052
David Bharucha
Chief Medical Officer
Dec 12, 2025Award+100,000––163,333
Lorenz Muller
Chief Commercial Officer
Dec 9, 2025Gift−25,000––150,052
Debra K. Liebert
Director
Jul 11, 2025Award+16,666––16,793
Joseph C. Papa
Director
Jul 11, 2025Award+100,000––100,000
Amit Hasija
CFO & EVP of Corp. Development
Jul 11, 2025Award+50,000––50,000
Lorenz Muller
Chief Commercial Officer
Jul 11, 2025Award+66,666––175,052
David Bharucha
Chief Medical Officer
Jul 11, 2025Award+53,333––63,333
Robert James Wills
Director
Jul 11, 2025Award+50,000––65,000
Joseph Oliveto
President and CEO, Director
Jul 11, 2025Award+66,666––347,221
Roderick Wong
10% owner
Mar 22, 2023Other−1,059,000––3,256,102
David Bharucha
Chief Medical Officer
Dec 5, 2022Buy+7,000$4.69$32.83K10,000
David Bharucha
Chief Medical Officer
Dec 1, 2022Buy+3,000$4.86$14.58K3,000
Debra K. Liebert
Director
Oct 21, 2022Buy+4,000$5.26$21.04K4,000
Richard C. Pasternak
Director
Oct 20, 2022Buy+10,000$5.20$52.00K10,000
Debra K. Liebert
Director
Oct 20, 2022Buy+10,000$5.29$52.90K10,000
Robert James Wills
Director
Oct 19, 2022Buy+15,000$4.93$73.95K15,000
Michael John Tomsicek
Director
Oct 19, 2022Buy+15,000$5.32$79.80K15,000
Debra K. Liebert
Director
Sep 14, 2022Other+127––127
Rtw Investments, Lp
10% owner
Sep 7, 2022Sale−1,557,346$8.71$13.56M4,315,102
Rtw Investments, Lp
10% owner
Sep 7, 2022Buy+1,557,346$8.71$13.56M4,315,102
Paul F. Truex
Director
May 31, 2022Option exercise+8,016$1.12$8.98K8,016
Paul F. Truex
Director
May 31, 2022Option exercise+45,072$1.54$69.41K53,088
Paul F. Truex
Director
May 31, 2022Option exercise+22,870$1.54$35.22K75,958
Paul F. Truex
Director
May 31, 2022Option exercise+822$2.66$2.19K76,780
Paul F. Truex
Director
May 31, 2022Buy+5,000$5.60$28.00K81,780
Lorenz Muller
Chief Commercial Officer
Aug 26, 2020Option exercise+5,700$1.54$8.78K108,386
De Solidarite Des Travailleurs Du Quebec Fonds
10% owner
Jul 29, 2020Sale−500,000$8.32$4.16M2,254,920
De Solidarite Des Travailleurs Du Quebec Fonds
10% owner
Jul 28, 2020Sale−19,863$8.10$160.89K2,754,920
Lorenz Muller
Chief Commercial Officer
Apr 3, 2020Option exercise+32,528$1.54$50.09K84,643
Lorenz Muller
Chief Commercial Officer
Apr 3, 2020Option exercise+18,043$1.54$27.79K102,686
Rtw Investments, Lp
10% owner
Mar 19, 2020Buy+5,870$10.87$63.81K4,315,102
Rtw Investments, Lp
10% owner
Mar 18, 2020Buy+2,705$10.36$28.02K4,309,232
Rtw Investments, Lp
10% owner
Mar 2, 2020Buy+78,263$18.95$1.48M4,306,527
Roderick Wong
10% owner
Jan 13, 2020Buy+270,000$16.25$4.39M4,228,264
Rtw Investments, Lp
10% owner
Dec 31, 2019Buy+21,438$15.50$332.29K3,958,264
Rtw Investments, Lp
10% owner
Dec 30, 2019Buy+1,333$15.48$20.63K3,936,826
Joseph Oliveto
President and CEO, Director
Dec 21, 2019Option exercise+7,400$1.54$11.40K280,555
Holdings A/S Novo
10% owner
Nov 25, 2019Sale−240,000$16.00$3.84M2,434,470

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
Oliveto Joseph
Director, Officer
Apr 16, 202636,500$80.30KApr 16, 2026Previously Exercised Stock Options
Oliveto Joseph
Director, Officer
Jan 8, 202679,500$170.93KJan 8, 2026Previously Exercised Stock Options
Oliveto Joseph
Officer
Jan 7, 2026500$1.03KJan 7, 2026Previously Exercised Stock Options