GYRENasdaqPharmaceutical PreparationsFiscal year ends December 31
GYRE THERAPEUTICS, INC.
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 7, 2026
$6.09+0.01 (+0.16%)
Close on Oct 19, 2026
- Market cap
- $612.88M
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
7.8%
9M of 112M shares
Institutional holders
60
12 new, 7 sold out
Net institutional buying
5M
In Q2 2026
Insider trades, 12 months
0 buys · 18 sales
Net sold $952.87K
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| GNI USA, Inc. | 86,323,015 | 69.10% | 13D (active) amendment | May 4, 2026 |
| Songjiang Ma | 7,342,131 | 6.33% | 13D (active) amendment | May 4, 2026 |
| Ying Luo | 10,211,387 | 8.60% | 13D (active) amendment | May 4, 2026 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of GYRE | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| HSG Holding Ltd | 3,750,299 | 3.36% | $24.71M | New | 1.99% |
| BlackRock, Inc. | 993,943 | 0.89% | $6.55M | +235,313 | 0.00% |
| Octagon Capital Advisors LP | 954,416 | 0.86% | $6.29M | New | 0.57% |
| Vanguard Capital Management LLC | 876,927 | 0.79% | $5.78M | −107,277 | 0.00% |
| Geode Capital Management, LLC | 532,950 | 0.48% | $3.51M | +101,536 | 0.00% |
| State Street Corp | 245,402 | 0.22% | $1.62M | +29,076 | 0.00% |
| Charles Schwab Investment Management Inc | 184,286 | 0.17% | $1.21M | +19,048 | 0.00% |
| Northern Trust Corp | 169,537 | 0.15% | $1.12M | +35,696 | 0.00% |
| SBI Securities Co., Ltd. | 166,750 | 0.15% | $1.10M | −4,087 | 0.02% |
| Vanguard Fiduciary Trust Co | 151,073 | 0.14% | $995.57K | +13,391 | 0.00% |
| Vanguard Portfolio Management LLC | 123,953 | 0.11% | $816.85K | +54,139 | 0.00% |
| Goldman Sachs Group Inc | 86,235 | 0.08% | $568.29K | +13,113 | 0.00% |
| Bank of New York Mellon Corp | 62,750 | 0.06% | $413.52K | +19,606 | 0.00% |
| Morgan Stanley | 41,691 | 0.04% | $274.74K | +33,050 | 0.00% |
| Strs Ohio | 25,800 | 0.02% | $170.02K | +4,700 | 0.00% |
| Dimensional Fund Advisors LP | 25,268 | 0.02% | $166.52K | – | 0.00% |
| Alliancebernstein L.P. | 24,590 | 0.02% | $171.39K | +2,760 | 0.00% |
| Nuveen, LLC | 24,505 | 0.02% | $161.49K | New | 0.00% |
| UBS Group AG | 18,763 | 0.02% | $123.65K | −2,324 | 0.00% |
| Millennium Management LLC | 18,488 | 0.02% | $121.84K | New | 0.00% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 60 | 9M | 7.8% | 12 / 31 | 9 / 7 | 5M | 0M |
| Q1 2026 | 56 | 3M | 3.1% | 15 / 18 | 11 / 2 | 1M | 0M |
| Q4 2025 | 44 | 3M | 3.0% | 2 / 22 | 9 / 6 | 0M | 0M |
| Q3 2025 | 48 | 3M | 2.8% | 10 / 13 | 16 / 10 | 0M | 0M |
| Q2 2025 | 48 | 3M | 3.1% | 10 / 25 | 8 / 7 | 1M | 0M |
| Q1 2025 | 45 | 3M | 2.3% | 8 / 15 | 14 / 3 | 1M | 0M |
| Q4 2024 | 40 | 2M | 1.6% | 5 / 16 | 12 / 2 | 0M | 0M |
| Q3 2024 | 37 | 2M | 1.4% | 12 / 14 | 6 / 4 | 1M | 0M |
| Q2 2024 | 30 | 1M | 1.1% | 16 / 7 | 6 / 7 | 1M | 0M |
| Q1 2024 | 21 | 1M | 0.8% | 10 / 6 | 4 / 4 | 0M | 0M |
| Q4 2023 | 15 | 1M | 0.5% | 15 / 0 | 0 / 0 | 1M | 0M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of GYRE | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 614,654 | 0.55% | $4.05M | 0.00% | Jun 30, 2026 |
| iShares Russell 2000 ETF | 394,330 | 0.35% | $2.60M | 0.00% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 238,693 | 0.21% | $1.57M | 0.00% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund | 199,906 | 0.18% | $1.15M | 0.00% | Jul 31, 2026 |
| iShares Russell 2000 Growth ETF | 120,729 | 0.11% | $795.60K | 0.01% | Jun 30, 2026 |
| Fidelity Extended Market Index Fund | 111,244 | 0.10% | $657.45K | 0.00% | May 31, 2026 |
| Schwab U.S. Small-Cap ETF | 99,892 | 0.09% | $590.36K | 0.00% | May 31, 2026 |
| Fidelity Nasdaq Composite Index Fund | 60,238 | 0.05% | $356.01K | 0.00% | May 31, 2026 |
| Vanguard Russell 2000 Index Fund | 60,098 | 0.05% | $355.18K | 0.00% | May 31, 2026 |
| Schwab Small-Cap Index Fund | 44,877 | 0.04% | $258.04K | 0.00% | Jul 31, 2026 |
| iShares Russell 2000 Value ETF | 41,653 | 0.04% | $274.49K | 0.00% | Jun 30, 2026 |
| Master Small Cap Index Series | 41,616 | 0.04% | $274.25K | 0.00% | Jun 30, 2026 |
| Fidelity Total Market Index Fund | 37,509 | 0.03% | $221.68K | 0.00% | May 31, 2026 |
| Fidelity Series Total Market Index Fund | 31,953 | 0.03% | $188.84K | 0.00% | May 31, 2026 |
| Nuveen Small Cap Blend Index Fund | 24,505 | 0.02% | $140.90K | 0.00% | Jul 31, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| Ying Luo | Chief Executive Officer, Director | 2,565,226 | 2.30% | Jun 10, 2026 |
| Songjiang Ma | President, Director | 2,806,084 | 2.52% | May 29, 2025 |
| Weiguo Ye | Chief Operating Officer | 700,000 | 0.63% | Jun 22, 2026 |
| Joshua Benjamin Bergmann | GC and Corporate Secretary | – | – | Jun 10, 2026 |
| Jialiang (NMN) Wang | EVP, General Manager | – | – | May 7, 2026 |
| Yue Xiong | Chief Scientific Officer | – | – | May 7, 2026 |
| Thomas Wilson Eastling | Chief Financial Officer | 15,000 | 0.01% | May 6, 2026 |
| Ruoyu Chen | Chief Financial Officer | – | – | Jan 9, 2026 |
| Maxwell Kirkby | Director | – | – | Aug 4, 2026 |
| Claire Weston | Director | – | – | Aug 4, 2026 |
| Renate Parry | Director | – | – | Jun 30, 2026 |
| Rodney L. Nussbaum | Director | – | – | Jun 30, 2026 |
| Dan Weng | Director | – | – | Jun 30, 2026 |
| Ping Zhang | Director | – | – | Jun 30, 2026 |
| Gordon Carmichael | Director | – | – | Jun 30, 2026 |
| David M. Epstein | Director | – | – | Jun 30, 2026 |
| GNI USA, Inc. | 10% owner | 64,005,887 | 57.40% | May 6, 2026 |
| Group Ltd. GNI | 10% owner | 6,266,521 | 5.62% | May 6, 2026 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Weiguo Ye Chief Operating Officer | Jun 18, 2026 | Sale | −3,000 | $6.35 | $19.05K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 18, 2026 | Option exercise | +3,000 | $0.75 | $2.25K | 703,000 |
| Weiguo Ye Chief Operating Officer | Jun 11, 2026 | Sale | −2,800 | $6.17 | $17.28K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 11, 2026 | Option exercise | +2,800 | $0.75 | $2.10K | 702,800 |
| Weiguo Ye Chief Operating Officer | Jun 10, 2026 | Option exercise | +5,000 | $0.75 | $3.75K | 705,000 |
| Weiguo Ye Chief Operating Officer | Jun 10, 2026 | Sale | −5,000 | $6.24 | $31.20K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 10, 2026 | Sale | −6,418 | $6.21 | $39.86K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 10, 2026 | Option exercise | +6,418 | $0.75 | $4.81K | 706,418 |
| Weiguo Ye Chief Operating Officer | Jun 9, 2026 | Option exercise | +3,000 | $0.75 | $2.25K | 703,000 |
| Weiguo Ye Chief Operating Officer | Jun 9, 2026 | Sale | −3,000 | $6.15 | $18.45K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 9, 2026 | Sale | −14,500 | $6.14 | $89.03K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 9, 2026 | Option exercise | +14,500 | $0.75 | $10.88K | 714,500 |
| Weiguo Ye Chief Operating Officer | Jun 5, 2026 | Option exercise | +15,401 | $0.75 | $11.55K | 715,401 |
| Weiguo Ye Chief Operating Officer | Jun 5, 2026 | Sale | −15,401 | $6.40 | $98.57K | 700,000 |
| Weiguo Ye Chief Operating Officer | Jun 4, 2026 | Option exercise | +19,575 | $0.75 | $14.68K | 719,575 |
| Weiguo Ye Chief Operating Officer | Jun 4, 2026 | Sale | −19,575 | $6.13 | $119.99K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 26, 2026 | Option exercise | +4,000 | $0.75 | $3.00K | 704,000 |
| Weiguo Ye Chief Operating Officer | May 26, 2026 | Sale | −4,000 | $6.10 | $24.40K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 22, 2026 | Option exercise | +3,500 | $0.75 | $2.63K | 703,500 |
| Weiguo Ye Chief Operating Officer | May 22, 2026 | Sale | −3,500 | $6.08 | $21.28K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 21, 2026 | Sale | −12,820 | $6.15 | $78.84K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 21, 2026 | Option exercise | +12,820 | $0.75 | $9.62K | 712,820 |
| Weiguo Ye Chief Operating Officer | May 20, 2026 | Sale | −9,400 | $6.15 | $57.81K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 20, 2026 | Option exercise | +9,400 | $0.75 | $7.05K | 709,400 |
| Weiguo Ye Chief Operating Officer | May 19, 2026 | Option exercise | +9,120 | $0.75 | $6.84K | 709,120 |
| Weiguo Ye Chief Operating Officer | May 19, 2026 | Sale | −9,120 | $6.37 | $58.09K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 18, 2026 | Sale | −200 | $6.62 | $1.32K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 18, 2026 | Option exercise | +200 | $0.75 | $150 | 700,200 |
| Weiguo Ye Chief Operating Officer | May 15, 2026 | Option exercise | +13,100 | $0.75 | $9.83K | 713,100 |
| Weiguo Ye Chief Operating Officer | May 15, 2026 | Sale | −13,100 | $6.65 | $87.12K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 14, 2026 | Sale | −15,580 | $6.91 | $107.66K | 700,000 |
| Weiguo Ye Chief Operating Officer | May 14, 2026 | Option exercise | +15,580 | $0.75 | $11.69K | 715,580 |
| Ying Luo Chief Executive Officer, Director | May 6, 2026 | Sale(10b5-1 plan) | −10,136 | $8.04 | $81.49K | 2,565,226 |
| Ying Luo Chief Executive Officer, Director | May 5, 2026 | Sale(10b5-1 plan) | −179 | $8.01 | $1.43K | 2,575,362 |
| Songjiang Ma President, Director | May 28, 2025 | Sale(10b5-1 plan) | −558 | $10.07 | $5.62K | 2,806,084 |
| Songjiang Ma President, Director | May 27, 2025 | Sale(10b5-1 plan) | −2,000 | $10.28 | $20.56K | 2,806,642 |
| Songjiang Ma President, Director | May 23, 2025 | Sale(10b5-1 plan) | −182 | $10.24 | $1.86K | 2,808,642 |
| Songjiang Ma President, Director | May 22, 2025 | Sale(10b5-1 plan) | −2,000 | $10.97 | $21.94K | 2,808,824 |
| Songjiang Ma President, Director | May 21, 2025 | Sale(10b5-1 plan) | −2,000 | $10.83 | $21.66K | 2,810,824 |
| Songjiang Ma President, Director | May 20, 2025 | Sale(10b5-1 plan) | −2,000 | $11.25 | $22.50K | 2,812,824 |
| Songjiang Ma President, Director | May 19, 2025 | Sale(10b5-1 plan) | −2,000 | $11.11 | $22.22K | 2,814,824 |
| Songjiang Ma President, Director | May 16, 2025 | Sale(10b5-1 plan) | −2,000 | $11.31 | $22.62K | 2,816,824 |
| Songjiang Ma President, Director | May 15, 2025 | Sale(10b5-1 plan) | −2,000 | $10.68 | $21.36K | 2,818,824 |
| Songjiang Ma President, Director | May 14, 2025 | Sale(10b5-1 plan) | −20 | $11.30 | $226 | 2,820,824 |
| Songjiang Ma President, Director | May 13, 2025 | Sale(10b5-1 plan) | −2,000 | $11.37 | $22.74K | 2,820,844 |
| Songjiang Ma President, Director | May 12, 2025 | Sale(10b5-1 plan) | −2,000 | $10.56 | $21.12K | 2,822,844 |
| Thomas Wilson Eastling Director | Apr 16, 2025 | Option exercise | +15,000 | $6.93 | $103.95K | 15,000 |
| Weiguo Ye Chief Operating Officer | Apr 1, 2025 | Option exercise | +50,000 | $0.75 | $37.50K | 700,000 |
| Weiguo Ye Chief Operating Officer | Mar 27, 2025 | Option exercise | +150,000 | $0.75 | $112.50K | 650,000 |
| Weiguo Ye Chief Operating Officer | Mar 26, 2025 | Option exercise | +200,000 | $0.75 | $150.00K | 500,000 |
| Weiguo Ye Chief Operating Officer | Mar 24, 2025 | Option exercise | +300,000 | $0.75 | $225.00K | 300,000 |
| Songjiang Ma President, Director | Mar 21, 2025 | Sale(10b5-1 plan) | −174 | $10.00 | $1.74K | 2,824,844 |
| Songjiang Ma President, Director | Mar 20, 2025 | Sale(10b5-1 plan) | −2,000 | $10.09 | $20.18K | 2,825,018 |
| Songjiang Ma President, Director | Mar 19, 2025 | Sale(10b5-1 plan) | −2,000 | $10.13 | $20.26K | 2,827,018 |
| Songjiang Ma President, Director | Mar 18, 2025 | Sale(10b5-1 plan) | −242 | $10.24 | $2.48K | 2,829,018 |
| Songjiang Ma President, Director | Mar 17, 2025 | Sale(10b5-1 plan) | −2,000 | $12.09 | $24.18K | 2,829,260 |
| Songjiang Ma President, Director | Mar 14, 2025 | Sale(10b5-1 plan) | −2,000 | $12.31 | $24.62K | 2,831,260 |
| Songjiang Ma President, Director | Mar 13, 2025 | Sale(10b5-1 plan) | −2,000 | $11.80 | $23.60K | 2,833,260 |
| Songjiang Ma President, Director | Mar 12, 2025 | Sale(10b5-1 plan) | −2,000 | $11.74 | $23.48K | 2,835,260 |
| Songjiang Ma President, Director | Mar 11, 2025 | Sale(10b5-1 plan) | −2,000 | $11.40 | $22.80K | 2,837,260 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.
Planned insider sales
Notices of proposed sale filed on Form 144 before shares are sold
| Seller | Filed | Shares | Market value | Planned sale | Acquired through |
|---|---|---|---|---|---|
| Weiguo Ye Officer | May 11, 2026 | 300,000 | $2.12M | May 13, 2026 | Stock Option Exercise |
| Weiguo Ye Officer | Nov 13, 2025 | 548,000 | $4.57M | Nov 15, 2025 | Stock Option Exercise |
| Usman Nassim Director | Jul 18, 2024 | 633 | $9.67K | Jul 18, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 17, 2024 | 3,347 | $51.33K | Jul 17, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 16, 2024 | 100 | $1.42K | Jul 16, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 15, 2024 | 4,900 | $68.99K | Jul 15, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 3, 2024 | 33 | $396 | Jul 3, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 2, 2024 | 7,767 | $93.99K | Jul 2, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jul 1, 2024 | 12,200 | $148.10K | Jul 1, 2024 | Stock Option Exercise |
| Usman Nassim Director | Jun 28, 2024 | 3,452 | $41.44K | Jun 28, 2024 | Stock Option Exercise |
| Usman Nassim Director | May 1, 2024 | 20,000 | $282.47K | May 1, 2024 | Stock Option Exercise |
| Wu Charles Officer, Director | Apr 9, 2024 | 2,154 | $36.68K | Apr 9, 2024 | Stock Option Exercise |
| Wu Charles Officer, Director | Apr 8, 2024 | 2,966 | $50.49K | Apr 8, 2024 | Stock Option Exercise |
| Wu Charles Officer, Director | Apr 5, 2024 | 1,412 | $24.05K | Apr 5, 2024 | Stock Option Exercise |
| Wu Charles Officer, Director | Apr 4, 2024 | 777 | $13.43K | Apr 4, 2024 | Stock Option Exercise |