StockData
CAINasdaqServices-Medical LaboratoriesFiscal year ends December 31

Caris Life Sciences, Inc.

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 5, 2026
$30.71+0.15 (+0.49%)

Close on Oct 19, 2026

Market cap
$8.69B
P/E (TTM)
–
Dividend yield
–

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
54.5%
154M of 283M shares
Institutional holders
246
69 new, 24 sold out
Net institutional buying
-3M
In Q2 2026
Insider trades, 12 months
4 buys · 7 sales
Net sold $27.26M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Abigail P. Johnson30,631,58510.80%13G (passive) amendmentMar 31, 2026
FMR LLC14,143,7685.00%13G (passive)Dec 31, 2025
David D. Halbert124,906,29644.10%13G (passive)Jun 30, 2025

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of CAIValueChange% of portfolio
FMR LLC30,923,87810.94%$551.06M+138,2930.02%
J. H. Whitney Equity Partners VI, LLC11,256,6153.98%$200.59M−7,000,000100.00%
Coatue Management LLC9,819,9923.47%$174.99M–0.36%
Braidwell LP8,256,0322.92%$147.12M+246,5855.44%
Sixth Street Partners Management Company, L.P.7,327,0412.59%$130.57M−7,058,35822.54%
PointState Capital LP6,828,8352.42%$121.69M−531,6111.56%
JPMorgan Chase & Co6,558,5142.32%$120.24M+3,098,2990.01%
BlackRock, Inc.5,536,7981.96%$98.67M+679,6860.00%
T. Rowe Price Investment Management, Inc.5,079,1411.80%$90.51K−509,1160.06%
Vanguard Portfolio Management LLC4,844,4311.71%$86.33M+1,085,9690.00%
Vanguard Capital Management LLC4,280,2381.51%$76.27M+951,2170.00%
Los Angeles Capital Management LLC3,958,5311.40%$70.54M+1,668,9290.26%
Neuberger Berman Group LLC3,590,9631.27%$63.99M+3770.04%
Orbimed Advisors LLC2,806,8110.99%$50.02M–0.93%
Bnp Paribas Arbitrage, Snc2,370,2680.84%$42.24M+755,9820.01%
Millennium Management LLC2,202,6470.78%$39.25M+674,8910.01%
Mak Capital One LLC1,937,2290.69%$34.52MNew4.84%
Morgan Stanley1,935,5310.68%$34.49M+856,1140.00%
Duquesne Family Office LLC1,894,4500.67%$33.76K–0.65%
Clearbridge Investments, LLC1,595,8770.56%$28.44M+44,1030.02%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 2026246154M54.5%69 / 10547 / 2423M26M
Q1 2026202157M55.5%57 / 8739 / 3642M35M
Q4 2025186149M52.8%77 / 6330 / 2755M19M
Q3 2025138114M40.4%53 / 4618 / 3112M7M
Q2 2025116109M38.7%116 / 00 / 0109M0M

Top mutual fund and ETF holders

Latest monthly portfolio reports (Form N-PORT)

FundShares% of CAIValue% of fundAs of
Vanguard Total Stock Market Index Fund4,047,8201.43%$72.13M0.00%Jun 30, 2026
Select Health Care Portfolio3,750,0001.33%$62.70M1.08%May 31, 2026
JPMorgan Mid Cap Growth Fund3,320,9831.18%$59.18M0.45%Jun 30, 2026
Fidelity Contrafund3,075,2201.09%$54.80M0.03%Jun 30, 2026
Select Medical Technology and Devices Portfolio3,000,0001.06%$50.16M1.68%May 31, 2026
Vanguard Small-Cap Index Fund2,921,3071.03%$52.06M0.03%Jun 30, 2026
Strategic Advisers Fidelity U.S. Total Stock Fund2,898,6001.03%$48.46M0.02%May 31, 2026
T. Rowe Price Mid-Cap Growth Fund, Inc.2,702,3790.96%$48.16M0.21%Jun 30, 2026
VIP Mid Cap Portfolio2,576,2700.91%$45.91M0.48%Jun 30, 2026
Vanguard Small-Cap Growth Index Fund1,686,0260.60%$30.04M0.06%Jun 30, 2026
Fidelity U.S. Equity Central Fund1,369,7110.48%$24.41M0.10%Jun 30, 2026
SMALLCAP World Fund Inc1,180,1730.42%$21.03M0.02%Jun 30, 2026
Fidelity Small Cap Growth Fund961,3400.34%$15.06M0.17%Jul 31, 2026
Fidelity Advisor Health Care Fund933,7490.33%$14.63M0.47%Jul 31, 2026
JNL/JPMorgan MidCap Growth Fund907,2940.32%$16.17M0.45%Jun 30, 2026

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
Brian J. BrilleSee Remarks, Director1,130,3030.40%Sep 17, 2026
David D. HalbertSee Remarks, Director, 10% owner123,599,53543.74%May 18, 2026
John Russel DentonSee Remarks184,0390.07%Sep 23, 2026
David Baxley SpetzlerPresident1,302,0830.46%Sep 4, 2026
Luke Thomas PowerSee Remarks153,7710.05%May 18, 2026
Laura I. JohansenDirector343,8970.12%Aug 14, 2026
T. Danny PhillipsDirector133,0600.05%Aug 14, 2026
David Paul FredricksonDirector31,8130.01%Aug 14, 2026
Peter M. CastlemanDirector10,683,7143.78%Aug 14, 2026
Jeff L. VacircaDirector62,8630.02%Aug 14, 2026
Jon HalbertDirector1,490,4060.53%Aug 14, 2026
Lloyd MinorDirector31,8130.01%Aug 14, 2026
Joseph E. GilliamDirector29,3210.01%Aug 14, 2026
Jonathan Kenneth Charles KnowlesDirector308,9790.11%Jun 2, 2026
George PosteDirector529,4310.19%Jun 2, 2026
Caris Halbert, L.P.Director, 10% owner123,462,09143.69%Jun 23, 2025
Paul R. Vigano10% owner––Jun 23, 2025
J. H. Whitney Equity Partners VI, LLC10% owner––Jun 23, 2025
H. Whitney VI L. P. J10% owner7,739,7812.74%Jun 23, 2025
Alan Waxman–––Jun 23, 2025
I. Ltd. ADAPT10% owner16,943,2326.00%Jun 23, 2025
Carisome I, L.P.10% owner––Jun 23, 2025
Sub-Fund HoldCo LLC TSSP–23,644,9078.37%Jun 23, 2025
Robert M. Williams Jr10% owner20,256,6157.17%Jun 23, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
John Russel Denton
See Remarks
Sep 22, 2026Sale−7,500$31.82$238.65K174,855
Brian J. Brille
See Remarks, Director
Sep 17, 2026Option exercise+400,000$2.44$976.00K630,303
Brian J. Brille
See Remarks, Director
Sep 17, 2026Sale−400,000$30.33$12.13M230,303
David Baxley Spetzler
President
Sep 4, 2026Option exercise+250,000$2.44$610.00K1,302,083
David Baxley Spetzler
President
Sep 4, 2026Sale−119,212$24.76$2.95M1,182,871
David Baxley Spetzler
President
Sep 3, 2026Sale−84,900$25.32$2.15M1,052,083
David Baxley Spetzler
President
Sep 3, 2026Sale−393,100$24.76$9.73M1,136,983
David Baxley Spetzler
President
Sep 3, 2026Option exercise+1,000,000$2.44$2.44M1,530,083
Lloyd Minor
Director
Aug 14, 2026Award+13,192––31,813
Jon Halbert
Director
Aug 14, 2026Award+13,192––131,813
Jeff L. Vacirca
Director
Aug 14, 2026Award+13,192––62,863
Laura I. Johansen
Director
Aug 14, 2026Award+13,192––343,897
Peter M. Castleman
Director
Aug 14, 2026Award+13,192––29,321
David Paul Fredrickson
Director
Aug 14, 2026Award+13,192––31,813
T. Danny Phillips
Director
Aug 14, 2026Award+13,192––133,060
Joseph E. Gilliam
Director
Aug 14, 2026Award+13,192––29,321
Jonathan Kenneth Charles Knowles
Director
May 29, 2026Award+1,600$15.62$24.99K308,979
George Poste
Director
May 29, 2026Award+1,600$15.62$24.99K17,729
Jon Halbert
Director
May 15, 2026Buy+68,000$14.56$990.08K704,598
Luke Thomas Power
See Remarks
May 15, 2026Tax withholding−9,771$15.25$149.01K153,771
David D. Halbert
See Remarks, Director, 10% owner
May 15, 2026Tax withholding−40,712$15.25$620.86K2,574,533
Brian J. Brille
See Remarks, Director
May 15, 2026Tax withholding−13,987$15.25$213.30K230,303
David Baxley Spetzler
President
May 15, 2026Tax withholding−13,856$15.25$211.30K530,083
John Russel Denton
See Remarks
May 15, 2026Tax withholding−6,047$15.25$92.22K181,515
Jeff L. Vacirca
Director
May 11, 2026Buy+31,050$16.15$501.46K49,671
Brian J. Brille
See Remarks, Director
Mar 6, 2026Award+83,162––244,290
Luke Thomas Power
See Remarks
Mar 6, 2026Award+63,971––163,542
David Baxley Spetzler
President
Mar 6, 2026Award+83,162––543,939
John Russel Denton
See Remarks
Mar 6, 2026Award+63,971––187,562
David D. Halbert
See Remarks, Director, 10% owner
Mar 6, 2026Award+320,112––2,615,245
Lloyd Minor
Director
Feb 26, 2026Award+2,492$20.06$49.99K18,621
Jon Halbert
Director
Feb 26, 2026Award+2,492$20.06$49.99K118,621
David Paul Fredrickson
Director
Feb 26, 2026Award+2,492$20.06$49.99K18,621
Jeff L. Vacirca
Director
Feb 26, 2026Award+2,492$20.06$49.99K18,621
Peter M. Castleman
Director
Feb 26, 2026Award+5,509$20.06$110.51K24,138
T. Danny Phillips
Director
Feb 26, 2026Award+3,739$20.06$75.00K119,868
Peter M. Castleman
Director
Jan 9, 2026Option exercise+2,500$18.60$46.50K18,629
Luke Thomas Power
See Remarks
Dec 11, 2025Option exercise+37,500$2.44$91.50K161,821
Luke Thomas Power
See Remarks
Dec 11, 2025Sale(10b5-1 plan)−60,850$26.56$1.62M100,971
Luke Thomas Power
See Remarks
Dec 11, 2025Sale(10b5-1 plan)−1,400$27.16$38.02K99,571
Luke Thomas Power
See Remarks
Dec 11, 2025Option exercise+24,750$2.44$60.39K124,321
Brian J. Brille
See Remarks, Director
Dec 11, 2025Gift−650––161,128
Brian J. Brille
See Remarks, Director
Dec 10, 2025Gift−650––161,778
John Russel Denton
See Remarks
Nov 7, 2025Buy+4,184$24.09$100.79K9,184
David Baxley Spetzler
President
Nov 7, 2025Buy+400$23.85$9.54K460,777
T. Danny Phillips
Director
Sep 11, 2025Option exercise+100,000$2.44$244.00K116,129
George Poste
Director
Aug 11, 2025Option exercise+125,000$2.44$305.00K359,754
George Poste
Director
Aug 11, 2025Tax withholding−48,022$29.75$1.43M311,732
George Poste
Director
Aug 11, 2025Tax withholding−91,495$29.75$2.72M220,237
David D. Halbert
See Remarks, Director, 10% owner
Aug 11, 2025Tax withholding−141,956$29.75$4.22M2,295,133
David Baxley Spetzler
President
Aug 11, 2025Tax withholding−63,509$29.75$1.89M460,377
John Russel Denton
See Remarks
Jun 20, 2025Buy+7,500$21.00$157.50K123,591
Caris Halbert, L.P.
Director, 10% owner
Jun 20, 2025Conversion+104,761,535––121,025,002
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Option exercise+1,711,113––5,687,176
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Conversion+10,103,175––10,103,175
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Option exercise+2,255,048––3,976,063
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Conversion+478,779––478,779
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Conversion+3,493,789––3,493,789
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Conversion+3,881,988––3,881,988
Sub-Fund HoldCo LLC TSSP
–
Jun 20, 2025Conversion+1,721,015––1,721,015

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
Russel Denton John
Officer
Sep 22, 20267,500$238.63KSep 22, 2026Private Acquisition from Issuer/Affiliate
J. Brille Brian
Officer, Director
Sep 17, 2026400,000$12.13MSep 17, 2026Exercise of Options Under a Registered Plan
Spetzler David
Officer
Sep 4, 2026119,212$2.95MSep 4, 2026Exercise of Options Under a Registered Plan
Spetzler David
Officer
Sep 3, 2026478,000$11.88MSep 3, 2026Exercise of Options Under a Registered Plan
H. Poste Revocable Trust George
Former Affiliate
Aug 24, 2026100,000$2.61MAug 24, 2026Previously Exercised Options
H. Poste George
Director
Aug 7, 202630,000$642.63KAug 7, 2026Stock Option Exercise
H. Poste George
Director
Aug 3, 202620,000$325.00KAug 3, 2026Stock Option Exercise
Power Luke
Officer
Dec 11, 202562,250$1.69MDec 11, 2025Exercise of Stock Options