AYTUNasdaqPharmaceutical PreparationsFiscal year ends June 30
AYTU BIOPHARMA, INC
Financials through Q4 FY2026, quarter ended Jun 30, 2026Last filing: 10-K on Sep 22, 2026
$1.96−0.08 (-3.92%)
Close on Oct 19, 2026
- Market cap
- $37.82M
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
45.3%
5M of 11M shares
Institutional holders
38
3 new, 2 sold out
Net institutional buying
1M
In Q2 2026
Insider trades, 12 months
0 buys · 0 sales
Open-market trades only
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| Stonepine Capital Management, LLC | 906,063 | 9.90% | 13G (passive) amendment | Jun 30, 2025 |
| Kanen David | 635,073 | 10.30% | 13G (passive) amendment | May 15, 2025 |
| AWM Investment Company, Inc. | 619,574 | 5.80% | 13G (passive) amendment | Dec 31, 2025 |
| Nantahala Capital Management, LLC | 1,086,812 | 14.40% | 13D (active) amendment | Jun 6, 2025 |
| Lytton Laurence W | 1,071,351 | 9.99% | 13G (passive) amendment | Dec 31, 2025 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of AYTU | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 2,173,624 | 20.00% | $4.67M | +1,086,812 | 0.08% |
| Stonepine Capital Management, LLC | 912,921 | 8.40% | $1.96M | +120,632 | 1.11% |
| AWM Investment Company, Inc. | 619,574 | 5.70% | $1.33M | – | 0.12% |
| Vanguard Capital Management LLC | 261,146 | 2.40% | $561.46K | – | 0.00% |
| Crown Advisors Management, Inc. | 200,000 | 1.84% | $430.00K | +55,000 | 0.24% |
| Diadema Partners LP | 148,546 | 1.37% | $319.37K | −204,531 | 0.04% |
| Two Sigma Investments, LP | 105,326 | 0.97% | $226.45K | −16,647 | 0.00% |
| Renaissance Technologies LLC | 104,823 | 0.96% | $225.37K | +11,100 | 0.00% |
| Geode Capital Management, LLC | 93,647 | 0.86% | $201.37K | +1,011 | 0.00% |
| Citadel Advisors LLC | 49,414 | 0.45% | $106.24K | +12,573 | 0.00% |
| Vanguard Fiduciary Trust Co | 47,048 | 0.43% | $101.15K | – | 0.00% |
| Dimensional Fund Advisors LP | 45,326 | 0.42% | $97.45K | +1,741 | 0.00% |
| Persistent Asset Partners Ltd | 37,984 | 0.35% | $81.67K | −54,913 | 0.02% |
| Northern Trust Corp | 27,925 | 0.26% | $60.04K | +8,756 | 0.00% |
| Bellevue Asset Management, LLC | 25,013 | 0.23% | $53.78K | – | 0.02% |
| BlackRock, Inc. | 22,793 | 0.21% | $49.01K | – | 0.00% |
| XTX Topco Ltd | 21,416 | 0.20% | $46.04K | −166 | 0.00% |
| Acadian Asset Management LLC | 10,237 | 0.09% | $22 | – | 0.00% |
| Daytona Street Capital LLC | 10,000 | 0.09% | $22.35K | – | 0.02% |
| UBS Group AG | 2,377 | 0.02% | $5.11K | +714 | 0.00% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 38 | 5M | 45.3% | 3 / 12 | 5 / 2 | 1M | 0M |
| Q1 2026 | 37 | 4M | 35.9% | 6 / 9 | 5 / 5 | 1M | 0M |
| Q4 2025 | 39 | 4M | 34.7% | 9 / 9 | 6 / 3 | 0M | 0M |
| Q3 2025 | 33 | 4M | 32.9% | 6 / 9 | 3 / 4 | 1M | 1M |
| Q2 2025 | 32 | 3M | 31.4% | 7 / 5 | 6 / 5 | 2M | 0M |
| Q1 2025 | 31 | 2M | 17.3% | 7 / 6 | 2 / 5 | 0M | 0M |
| Q4 2024 | 29 | 2M | 17.3% | 7 / 5 | 5 / 2 | 0M | 0M |
| Q3 2024 | 24 | 2M | 18.9% | 1 / 4 | 8 / 3 | 0M | 1M |
| Q2 2024 | 27 | 3M | 28.9% | 3 / 7 | 6 / 3 | 1M | 0M |
| Q1 2024 | 27 | 2M | 16.5% | 6 / 7 | 5 / 1 | 0M | 1M |
| Q4 2023 | 22 | 3M | 26.4% | 2 / 9 | 6 / 2 | 1M | 0M |
| Q3 2023 | 22 | 2M | 15.9% | 3 / 5 | 6 / 2 | 0M | 0M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of AYTU | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 169,000 | 1.56% | $363.35K | 0.00% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 92,146 | 0.85% | $198.11K | 0.00% | Jun 30, 2026 |
| Fidelity Extended Market Index Fund | 50,229 | 0.46% | $115.02K | 0.00% | May 31, 2026 |
| Fidelity Series Total Market Index Fund | 11,929 | 0.11% | $27.32K | 0.00% | May 31, 2026 |
| Fidelity Total Market Index Fund | 9,757 | 0.09% | $22.34K | 0.00% | May 31, 2026 |
| U.S. Vector Equity Portfolio | 5,481 | 0.05% | $12.22K | 0.00% | Jul 31, 2026 |
| Dimensional US Sustainability Core 1 ETF | 4,805 | 0.04% | $10.72K | 0.00% | Jul 31, 2026 |
| U.S. Sustainability Core 1 Portfolio | 4,640 | 0.04% | $10.35K | 0.00% | Jul 31, 2026 |
| Dimensional U.S. Small Cap ETF | 4,402 | 0.04% | $9.82K | 0.00% | Jul 31, 2026 |
| Dimensional U.S. Core Equity 2 ETF | 4,122 | 0.04% | $9.19K | 0.00% | Jul 31, 2026 |
| U.S. Core Equity 1 Portfolio | 4,100 | 0.04% | $9.14K | 0.00% | Jul 31, 2026 |
| Dimensional US Core Equity 1 ETF | 2,147 | 0.02% | $4.79K | 0.00% | Jul 31, 2026 |
| U.S. Social Core Equity 2 Portfolio | 1,741 | 0.02% | $3.88K | 0.00% | Jul 31, 2026 |
| U.S. Core Equity 2 Portfolio | 1,710 | 0.02% | $3.81K | 0.00% | Jul 31, 2026 |
| Omni Small-Cap Value Fund | 1,500 | 0.01% | $3.23K | 0.00% | Jun 30, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| Joshua R. Disbrow | Chief Executive Officer, Director | 237,203 | 2.18% | Jul 30, 2026 |
| Greg Pyszczymuka | Chief Commercial Officer | 56,102 | 0.52% | Jul 30, 2026 |
| Jarrett Disbrow | Chief Business Officer | 76,568 | 0.70% | Jul 30, 2026 |
| Ryan J. Selhorn | Chief Financial Officer | 74,743 | 0.69% | Jul 30, 2026 |
| Vivian H. Liu | Director | 29,825 | 0.27% | Jul 30, 2026 |
| Carl Dockery | Director | 31,202 | 0.29% | Jul 30, 2026 |
| John Donofrio Jr. | Director | 23,762 | 0.22% | Jul 30, 2026 |
| Abhinav Jain | Director | 29,500 | 0.27% | Jul 30, 2026 |
| Nantahala Capital Management, LLC | 10% owner | 1,086,812 | 10.00% | Jun 9, 2025 |
| Daniel Mack | 10% owner | – | – | Jun 9, 2025 |
| Wilmot B. Harkey | 10% owner | – | – | Jun 9, 2025 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Ryan J. Selhorn Chief Financial Officer | Jul 28, 2026 | Award | +25,000 | – | – | 74,743 |
| Jarrett Disbrow Chief Business Officer | Jul 28, 2026 | Award | +15,000 | – | – | 76,568 |
| Abhinav Jain Director | Jul 28, 2026 | Award | +10,000 | – | – | 29,500 |
| John Donofrio Jr. Director | Jul 28, 2026 | Award | +10,000 | – | – | 23,762 |
| Joshua R. Disbrow Chief Executive Officer, Director | Jul 28, 2026 | Award | +30,000 | – | – | 237,203 |
| Greg Pyszczymuka Chief Commercial Officer | Jul 28, 2026 | Award | +20,000 | – | – | 56,102 |
| Carl Dockery Director | Jul 28, 2026 | Award | +10,000 | – | – | 31,152 |
| Vivian H. Liu Director | Jul 28, 2026 | Award | +10,000 | – | – | 29,825 |
| Greg Pyszczymuka Chief Commercial Officer | Oct 3, 2025 | Award | +12,500 | – | – | 36,102 |
| Vivian H. Liu Director | Oct 3, 2025 | Award | +10,000 | – | – | 19,825 |
| Ryan J. Selhorn Chief Financial Officer | Oct 3, 2025 | Award | +17,500 | – | – | 49,743 |
| Ryan J. Selhorn Chief Financial Officer | Oct 3, 2025 | Award | +16,243 | – | – | 32,243 |
| Carl Dockery Director | Oct 3, 2025 | Award | +10,000 | – | – | 20,440 |
| Joshua R. Disbrow Chief Executive Officer, Director | Oct 3, 2025 | Award | +22,500 | – | – | 207,203 |
| Joshua R. Disbrow Chief Executive Officer, Director | Oct 3, 2025 | Award | +31,446 | – | – | 184,703 |
| John Donofrio Jr. Director | Oct 3, 2025 | Award | +10,000 | – | – | 13,762 |
| Abhinav Jain Director | Oct 3, 2025 | Award | +10,000 | – | – | 19,500 |
| Jarrett Disbrow Chief Business Officer | Oct 3, 2025 | Award | +19,606 | – | – | 49,068 |
| Jarrett Disbrow Chief Business Officer | Oct 3, 2025 | Award | +12,500 | – | – | 61,568 |
| Joshua R. Disbrow Chief Executive Officer | Jun 9, 2025 | Buy | +66,666 | $1.50 | $100.00K | 153,257 |
| Jarrett Disbrow Chief Business Officer | Jun 9, 2025 | Buy | +16,666 | $1.50 | $25.00K | 29,462 |
| Greg Pyszczymuka Chief Commercial Officer | Mar 31, 2025 | Option exercise | +209 | – | – | 23,602 |
| Joshua R. Disbrow Chief Executive Officer | Feb 28, 2025 | Buy | +15,000 | $1.30 | $19.50K | 86,591 |
| Ryan J. Selhorn Chief Financial Officer | Feb 5, 2025 | Option exercise | +105 | – | – | 16,000 |
| Greg Pyszczymuka Chief Commercial Officer | Dec 31, 2024 | Option exercise | +208 | – | – | 23,393 |
| Ryan J. Selhorn Chief Financial Officer | Nov 11, 2024 | Award | +14,000 | – | – | 15,895 |
| Vivian H. Liu Director | Nov 6, 2024 | Award | +1,500 | – | – | 9,825 |
| Abhinav Jain Director | Nov 6, 2024 | Award | +1,500 | – | – | 9,500 |
| Carl Dockery Director | Nov 6, 2024 | Award | +1,500 | – | – | 10,440 |
| John Donofrio Jr. Director | Nov 6, 2024 | Award | +1,500 | – | – | 3,762 |
| Greg Pyszczymuka Chief Commercial Officer | Sep 30, 2024 | Option exercise | +209 | – | – | 23,185 |
| Greg Pyszczymuka Chief Commercial Officer | Jun 30, 2024 | Option exercise | +208 | – | – | 22,976 |
| Greg Pyszczymuka Chief Commercial Officer | Mar 31, 2024 | Option exercise | +208 | – | – | 22,768 |
| Greg Pyszczymuka Chief Commercial Officer | Dec 31, 2023 | Option exercise | +209 | – | – | 22,560 |
| Greg Pyszczymuka Chief Commercial Officer | Sep 30, 2023 | Option exercise | +208 | – | – | 22,351 |
| Abhinav Jain Director | Aug 16, 2023 | Award | +6,500 | – | – | 8,000 |
| Vivian H. Liu Director | Aug 11, 2023 | Award | +1,500 | – | – | 8,325 |
| John Donofrio Jr. Director | Aug 11, 2023 | Award | +1,500 | – | – | 2,262 |
| Carl Dockery Director | Aug 11, 2023 | Award | +1,500 | – | – | 8,940 |
| Vivian H. Liu Director | Aug 11, 2023 | Award | +1,500 | – | – | 1,841 |
| Abhinav Jain Director | Aug 11, 2023 | Award | +1,500 | – | – | 1,500 |
| Greg Pyszczymuka Chief Commerical Officer | Jun 30, 2023 | Option exercise | +208 | – | – | 22,143 |
| Greg Pyszczymuka Chief Commerical Officer | Jun 16, 2023 | Buy | +12,000 | $1.87 | $22.44K | 21,935 |
| Joshua R. Disbrow Chief Executive Officer, Director | Jun 14, 2023 | Buy | +14,000 | $1.86 | $26.04K | 71,591 |
| Greg Pyszczymuka Chief Commerical Officer | Apr 25, 2023 | Option exercise | +833 | – | – | 9,935 |
| Vivian H. Liu Director | Feb 8, 2023 | Award | +6,500 | – | – | 6,825 |
| John Donofrio Jr. Director | Dec 21, 2022 | Returned to company | −187,804 | – | – | 15,267 |
| Carl Dockery Director | Dec 21, 2022 | Returned to company | −40,000 | – | – | 148,805 |
| Gary Cantrell Director | Dec 21, 2022 | Returned to company | −40,000 | – | – | 164,089 |
| Joshua R. Disbrow Chief Executive Officer, Director | Dec 20, 2022 | Returned to company | −80,000 | – | – | 1,151,877 |
| Joshua R. Disbrow Chief Executive Officer, Director | Dec 19, 2022 | Buy | +112,371 | $0.22 | $24.72K | 1,231,877 |
| Greg Pyszczymuka Chief Commercial Officer | Dec 19, 2022 | Buy | +100,000 | $0.24 | $24.00K | 182,056 |
| Mark K. Oki Chief Financial Officer | Nov 18, 2022 | Buy | +90,000 | $0.23 | $20.70K | 190,000 |
| Joshua R. Disbrow Chief Executive Officer, Director | Nov 18, 2022 | Buy | +222,000 | $0.24 | $53.28K | 1,119,506 |
| Joshua R. Disbrow Chief Executive Officer, Director | Nov 18, 2022 | Award | +222,000 | $0.24 | $53.28K | 1,119,506 |
| Mark K. Oki Chief Financial Officer | Nov 18, 2022 | Award | +90,000 | $0.23 | $20.70K | 190,000 |
| Vivian H. Liu Director | Jul 1, 2022 | Award | +6,500 | – | – | 6,500 |
| Mark K. Oki Chief Financial Officer | Jan 17, 2022 | Award | +100,000 | – | – | 100,000 |
| John Donofrio Jr. Director | Apr 16, 2021 | Award | +187,804 | – | – | 203,071 |
| Gary Cantrell Director | Apr 16, 2021 | Award | +187,804 | – | – | 204,089 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.