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ANABNasdaqPharmaceutical PreparationsFiscal year ends June 30

ANAPTYSBIO, INC

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on May 12, 2026
$49.24+2.63 (+5.64%)

Close on Oct 19, 2026

Market cap
$2.28B
P/E (TTM)
–
Dividend yield
–

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
100.0%
30M of 30M shares
Institutional holders
213
46 new, 37 sold out
Net institutional buying
2M
In Q2 2026
Insider trades, 12 months
0 buys · 41 sales
Net sold $9.50M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Oleg Nodelman7,794,99625.80%13D (active) amendmentAug 14, 2024
Tang Capital Management, LLC1,950,6097.30%13G (passive) amendmentDec 31, 2023
Alex Silverstein1,920,4026.70%13G (passive)Mar 31, 2026
BlackRock, Inc.1,900,8446.20%13G (passive) amendmentMar 31, 2025
Steven A. Cohen1,691,3725.60%13G (passive)Feb 14, 2025
Sirenia Capital Management LP1,491,9595.00%13G (passive) amendmentJun 30, 2026
Millennium Group Management LLC1,426,8935.10%13G (passive)Sep 16, 2025

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of ANABValueChange% of portfolio
EcoR1 Capital, LLC7,880,09426.36%$531.91M–25.86%
BlackRock, Inc.1,844,0496.17%$124.47M+162,6690.00%
Tang Capital Management LLC1,330,8794.45%$89.83M–4.08%
State Street Corp1,286,1944.30%$86.82M+293,7490.00%
Vanguard Capital Management LLC906,2333.03%$61.17M+53,0820.00%
Affinity Asset Advisors, LLC826,1092.76%$55.76M−113,8912.52%
Sanofi821,9172.75%$55.48M–10.39%
Millennium Management LLC807,3162.70%$54.49M+331,7440.02%
Woodline Partners LP717,0142.40%$48.40M+372,7580.15%
683 Capital Management, LLC660,0002.21%$44.55M+35,0002.19%
Geode Capital Management, LLC637,8732.13%$43.06M+117,6320.00%
Palo Alto Investors LP603,4892.02%$40.74M−34,6725.63%
Goldman Sachs Group Inc584,0701.95%$39.42M+251,3270.00%
First Light Asset Management, LLC582,0041.95%$39.29M+16,5732.39%
D. E. Shaw & Co., Inc.539,6661.81%$36.43M−39,6300.02%
Vanguard Portfolio Management LLC527,8581.77%$35.63M+7,9880.00%
Apis Capital Advisors, LLC497,0001.66%$33.55M+259,0003.27%
Sofinnova Investments, Inc.493,5361.65%$33.31M+245,2831.72%
Arrowstreet Capital, Limited Partnership488,6511.63%$32.98M−3,4690.01%
Nuveen, LLC420,6641.41%$28.39M+104,5990.01%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 202621330M100.0%46 / 7365 / 375M3M
Q1 202620828M94.5%51 / 5970 / 205M5M
Q4 202517929M98.2%37 / 5164 / 243M5M
Q3 202516632M100.0%35 / 4359 / 155M9M
Q2 202514737M100.0%27 / 4654 / 315M9M
Q1 202515340M100.0%45 / 4443 / 2613M8M
Q4 202413535M100.0%27 / 5035 / 528M6M
Q3 202416034M100.0%38 / 6131 / 118M2M
Q2 202413530M99.7%26 / 4345 / 236M7M
Q1 202413331M100.0%26 / 4140 / 124M4M
Q4 202311931M100.0%16 / 3243 / 134M3M
Q3 202311630M100.0%14 / 3438 / 144M4M

Top mutual fund and ETF holders

Latest monthly portfolio reports (Form N-PORT)

FundShares% of ANABValue% of fundAs of
State Street(R) SPDR(R) S&P(R) Biotech ETF786,6272.63%$53.10M0.49%Jun 30, 2026
Vanguard Total Stock Market Index Fund648,1462.17%$43.75M0.00%Jun 30, 2026
iShares Russell 2000 ETF514,9451.72%$34.76M0.04%Jun 30, 2026
Nuveen Quant Small Cap Equity Fund263,8400.88%$14.08M0.35%Jul 31, 2026
Vanguard Extended Market Index Fund237,0320.79%$16.00M0.02%Jun 30, 2026
Fidelity Small Cap Index Fund215,8730.72%$11.52M0.03%Jul 31, 2026
Federated Hermes Kaufmann Small Cap Fund210,0000.70%$11.21M0.39%Jul 31, 2026
iShares Biotechnology ETF193,5280.65%$13.06M0.14%Jun 30, 2026
Victory Science & Technology Fund187,8930.63%$10.03M0.67%Jul 31, 2026
iShares Russell 2000 Growth ETF185,5480.62%$12.52M0.08%Jun 30, 2026
Burney U.S. Equity Select ETF148,9430.50%$7.95M1.18%Jul 31, 2026
Vanguard Strategic Equity Fund131,2650.44%$8.86M0.07%Jun 30, 2026
First Trust Small Cap Growth AlphaDEX Fund130,0110.43%$6.94M0.53%Jul 31, 2026
Federated Hermes MDT Small Cap Core Fund127,7040.43%$6.81M0.30%Jul 31, 2026
Burney U.S. Factor Rotation ETF123,9690.41%$6.61M1.14%Jul 31, 2026

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
Daniel FagaPresident, CEO, Director510,5641.71%Aug 7, 2026
Paul F. LizzulChief Medical Officer42,0880.14%Aug 7, 2026
Christopher M. MurphyChief Financial Officer––May 13, 2026
Eric J. LoumeauCHIEF LEGAL OFFICER12,8350.04%Feb 13, 2026
Dennis MulroyCHIEF FINANCIAL OFFICER21,8520.07%Jan 9, 2026
John A. OrwinDirector17,9950.06%Sep 17, 2026
John P. SchmidDirector37,6520.13%Jun 17, 2026
Hollings RentonDirector10,9950.04%Jun 17, 2026
Owen HughesDirector––May 13, 2026
Susannah GrayDirector––Apr 29, 2026
Magda MarquetDirector20,9300.07%Jan 16, 2026
J. Anthony WareDirector9,6300.03%Jan 8, 2026
Rita JainDirector11,8640.04%Jan 8, 2026
Dennis M. FentonDirector4,9650.02%Jan 8, 2026
EcoR1 Capital, LLCDirector, 10% owner7,880,09426.36%Jan 2, 2025
Oleg NodelmanDirector, 10% owner7,520,42425.16%Jan 2, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
John A. Orwin
Director
Sep 15, 2026Option exercise+1,300––17,995
John A. Orwin
Director
Jun 15, 2026Option exercise+6,030––16,695
John P. Schmid
Director
Jun 15, 2026Option exercise+6,030––37,652
Hollings Renton
Director
Jun 15, 2026Option exercise+6,030––10,995
John P. Schmid
Director
Mar 30, 2026Sale−522$57.40$29.96K31,622
John P. Schmid
Director
Mar 30, 2026Sale−7,527$56.70$426.78K32,144
John P. Schmid
Director
Mar 30, 2026Sale−12,596$55.71$701.72K39,671
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−2,570$57.91$148.83K510,564
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−510$56.61$28.87K513,134
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−3,662$58.62$214.67K506,902
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−490$59.62$29.21K506,412
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−550$60.63$33.35K505,862
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−1,012$62.15$62.90K504,850
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−2,592$63.35$164.20K502,258
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−3,155$64.19$202.52K499,103
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−3,038$65.20$198.08K496,065
Daniel Faga
President, CEO, Director
Mar 27, 2026Sale−100$65.99$6.60K495,965
Daniel Faga
President, CEO, Director
Mar 25, 2026Award+34,300––513,644
Eric J. Loumeau
CHIEF LEGAL OFFICER
Feb 11, 2026Sale(10b5-1 plan)−10,000$54.00$540.00K12,835
Eric J. Loumeau
CHIEF LEGAL OFFICER
Feb 11, 2026Option exercise+10,000$29.70$297.00K22,835
Magda Marquet
Director
Jan 15, 2026Option exercise+11,000$26.11$287.21K20,930
Magda Marquet
Director
Jan 15, 2026Sale−1,710$48.85$83.53K9,930
Magda Marquet
Director
Jan 15, 2026Sale−9,290$48.12$447.03K11,640
Daniel Faga
President, CEO, Director
Jan 8, 2026Sale−14,281$44.71$638.50K479,344
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 8, 2026Sale−2,515$44.71$112.45K21,852
Paul F. Lizzul
Chief Medical Officer
Jan 8, 2026Sale−3,650$44.71$163.19K42,088
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 8, 2026Sale−2,210$44.71$98.81K12,835
Daniel Faga
President, CEO, Director
Jan 7, 2026Option exercise+26,838––493,625
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 7, 2026Option exercise+6,700––24,367
Paul F. Lizzul
Chief Medical Officer
Jan 7, 2026Option exercise+8,525––45,738
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 7, 2026Option exercise+5,888––15,045
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 7, 2026Sale(10b5-1 plan)−1,841$46.13$84.93K9,657
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 7, 2026Sale(10b5-1 plan)−500$47.23$23.62K9,157
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 7, 2026Sale(10b5-1 plan)−5,281$45.38$239.65K11,498
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 7, 2026Sale(10b5-1 plan)−2,017$45.11$90.99K16,779
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 7, 2026Sale−1,908$45.11$86.07K17,667
Paul F. Lizzul
Chief Medical Officer
Jan 7, 2026Sale−2,235$45.11$100.82K37,213
Daniel Faga
President, CEO, Director
Jan 7, 2026Sale−9,202$45.11$415.10K466,787
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 6, 2026Option exercise+5,545––18,796
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 6, 2026Option exercise+5,245––19,575
Paul F. Lizzul
Chief Medical Officer
Jan 6, 2026Option exercise+6,145––39,448
Daniel Faga
President, CEO, Director
Jan 6, 2026Option exercise+17,850––475,989
Paul F. Lizzul
Chief Medical Officer
Jan 5, 2026Sale−4,219$43.26$182.51K33,303
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 5, 2026Sale−2,983$43.26$129.04K13,251
Daniel Faga
President, CEO, Director
Jan 5, 2026Sale−15,309$43.26$662.27K458,139
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 5, 2026Sale−3,363$43.26$145.48K14,330
Paul F. Lizzul
Chief Medical Officer
Jan 3, 2026Option exercise+10,555––37,522
Eric J. Loumeau
CHIEF LEGAL OFFICER
Jan 3, 2026Option exercise+7,287––16,234
Daniel Faga
President, CEO, Director
Jan 3, 2026Option exercise+34,677––473,448
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Jan 3, 2026Option exercise+8,292––17,693
J. Anthony Ware
Director
Dec 23, 2025Sale−3,900$49.58$193.36K9,630
John P. Schmid
Director
Dec 23, 2025Other−11,068$51.00$564.47K0
Paul F. Lizzul
Chief Medical Officer
Dec 22, 2025Sale(10b5-1 plan)−1,500$50.00$75.00K26,967
Paul F. Lizzul
Chief Medical Officer
Dec 22, 2025Option exercise+1,500$18.50$27.75K28,467
Eric J. Loumeau
CHIEF LEGAL OFFICER
Dec 22, 2025Option exercise+10,000$14.02$140.20K18,947
Eric J. Loumeau
CHIEF LEGAL OFFICER
Dec 22, 2025Sale(10b5-1 plan)−10,000$51.00$510.00K8,947
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Dec 22, 2025Option exercise+10,000$20.16$201.60K19,401
Dennis Mulroy
CHIEF FINANCIAL OFFICER
Dec 22, 2025Sale(10b5-1 plan)−10,000$50.00$500.00K9,401
Eric J. Loumeau
CHIEF LEGAL OFFICER
Dec 18, 2025Sale(10b5-1 plan)−141$46.99$6.63K8,947
Eric J. Loumeau
CHIEF LEGAL OFFICER
Dec 17, 2025Option exercise+10,000$14.02$140.20K19,088

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
C. Renton Hollings
Director
Oct 1, 20265,000$249.37KOct 1, 2026Stock Option Exercise
Anthony Ware Joe
Director
Jul 13, 202610,694$718.33KJul 13, 2026Stock Option Exercise
Anthony Ware Joe
Director
Jun 30, 20266,030$408.77KJun 30, 2026Restricted Stock
Mulroy Dennis
Officer
Jun 29, 20269,476$601.21KJun 29, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 26, 202610,000$608.18KJun 26, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 17, 2026850$51.00KJun 17, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 16, 20261,265$75.90KJun 16, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 15, 202620,000$1.15MJun 15, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 12, 202620,000$1.11MJun 12, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 11, 202635,000$1.85MJun 11, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 10, 202620,000$1.05MJun 10, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 9, 202620,000$1.03MJun 9, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 8, 202621,987$1.12MJun 8, 2026Restricted Stock
Mulroy Dennis
Officer
Jun 5, 202622,491$1.15MJun 5, 2026Stock Option Exercise
Mulroy Dennis
Officer
Jun 5, 202620,000$1.04MJun 4, 2026Stock Option Exercise