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Zymeworks Inc. (ZYME) stock

ZYMENasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 9, 2026Score 10/30141% above fair value
$26.47−2.60 (-8.94%)

Close on Nov 12, 2026Market cap $1.88BP/E 50.9Yield –

Zymeworks statistics

87 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.

Important dates

Next earnings
Mar 1, 2027 (estimated, before the open)
Last ex-dividend date
No dividends
Fundamentals through
Sep 30, 2026
Share price as of
Nov 11, 2026

Valuation ratiosIndustry

Market Cap
$2.06B
$289.51M
Enterprise Value
$1.96B
$155.84M
PE Ratio
55.90
25.08
PS Ratio
7.76
3.68
PB Ratio
7.99
2.13
P/TBV Ratio
14.63
2.38

Enterprise valuationIndustry

EV / Sales
7.38
2.65
EV / EBITDA
44.45
16.59
EV / EBIT
44.45
19.15

Share statisticsIndustry

Shares Change (YoY)
-1.26%
10.9%
Shares Change (QoQ)
-0.33%
0.48%
Float
29M
49M
Shares Held by Insiders
58.9%
12.1%
Shares Held by Institutions
98.1%
56.4%

Short sellingIndustry

Short Interest
6M
–
Short Interest Change
6.04%
-0.80%
Short % of Float
20.3%
9.06%
Short % of Shares Outstanding
8.34%
6.30%
Days to Cover
4.25
5.15

Stock price statisticsIndustry

52-Week High
$31.97
–
52-Week Low
$18.20
–
20-Day Moving Average
$28.56
–
50-Day Moving Average
$27.48
–
200-Day Moving Average
$25.48
–
Average True Range (14)
$1.38
–
Price Change (1 Week)
-6.04%
-0.58%
Price Change (1 Month)
16.0%
-0.28%
Price Change (3 Months)
12.8%
-17.1%
Price Change (6 Months)
18.3%
-20.1%
Price Change (YTD)
10.4%
-20.1%
Price Change (1 Year)
61.1%
-19.3%
Price Change (3 Years)
299.9%
-22.2%
Price Change (5 Years)
44.3%
-76.4%
Average Volume (10 Days)
1M
–
Average Volume (20 Days)
1M
–
Average Volume (90 Days)
883,540
–
Relative Volume
1.11
0.73
Relative Strength Index (14)
52.8
47.7
Volatility (1 Year)
54.1%
80.2%
Beta (5 Years)
0.84
1.08

MarginsIndustry

Operating Margin
16.6%
-38.5%
Pretax Margin
15.1%
-11.8%
Profit Margin
16.3%
-31.7%
EBITDA Margin
16.6%
-27.7%
FCF Margin
-42.4%
-8.85%

Returns on capitalIndustry

Return on Equity (ROE)
15.0%
-51.3%
Return on Assets (ROA)
5.50%
-40.7%
Return on Invested Capital (ROIC)
21.4%
-32.9%
Return on Capital Employed (ROCE)
4.35%
-38.1%

Financial positionIndustry

Current Ratio
3.30
3.30
Quick Ratio
3.19
2.40

GrowthIndustry

Revenue Growth (YoY)
97.8%
7.26%
Revenue Growth (3Y CAGR)
-36.4%
2.25%
Revenue Growth (5Y CAGR)
22.2%
6.41%

EfficiencyIndustry

Asset Turnover
0.34
0.40
Revenue Per Employee
$1.01M
$429.38K
Profits Per Employee
$164.05K
-$683.67K
Employee Count
264
75
WACC
9.10%
10.1%

Income statement (TTM)Industry

Revenue
$265.97M
$66.69M
Operating Income
$44.15M
-$20.99M
Pretax Income
$40.12M
-$13.23M
Net Income
$43.31M
-$21.61M
EBITDA
$44.15M
-$16.85M
EPS (Diluted)
$0.52
-$0.75

Balance sheetIndustry

Net Cash (Debt)
$100.46M
$16.56M
Net Cash Per Share
$1.42
$0.71
Equity (Book Value)
$258.25M
$52.23M
Book Value Per Share
$3.64
$1.50
Tangible Book Value
$141.03M
$26.10M
Working Capital
$370.94M
$78.41M

Cash flow (TTM)Industry

Operating Cash Flow
-$111.96M
-$12.27M
Capital Expenditures
-$870.00K
-$944.00K
Free Cash Flow
-$112.83M
-$18.20M
FCF Per Share
-$1.59
-$0.42

Dividends and yieldsIndustry

Earnings Yield
2.10%
-20.1%
FCF Yield
-5.47%
-9.14%
Buyback Yield
8.03%
-0.69%
Shareholder Yield
8.03%
0.00%

Taxes and interestIndustry

Income Tax
-$3.19M
$74.00K
Effective Tax Rate
-7.94%
20.9%

Scores and fair valueIndustry

Graham Number
$6.53
$19.34
Graham Upside
-77.6%
-46.9%
Altman Z-Score
0.87
0.31
Piotroski F-Score
6
4

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodZYMES&P 500DifferenceZYME per yearS&P 500 per year
1 month+4.5%-2.7%+7.2 pts
3 months+6.2%-1.7%+7.9 pts
Year to date+0.5%+11.9%−11.4 pts
1 year+36.7%+12.0%+24.7 pts
3 years+263.1%+78.2%+184.9 pts+53.7%+21.2%
5 years+31.4%+73.2%−41.9 pts+5.6%+11.6%

Short interest

Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.

6M ZYME shares were sold short on Oct 30, 2026, up 6.0% from the previous report, or 20.29% of the shares available to trade. At recent volumes it would take 4.3 days to buy them back. Over the last 20 sessions, 58.7% of the volume reported to FINRA was short selling.

Settlement dateShares shortChangeAvg. daily volumeDays to cover
Oct 30, 20265,914,601+6.0%1,392,5624.3
Oct 15, 20265,577,540+5.4%1,279,8384.4
Sep 30, 20265,291,136+7.1%953,9285.5
Sep 15, 20264,939,072+4.5%619,9148.0
Aug 31, 20264,724,831+4.1%827,5755.7
Aug 14, 20264,538,353+10.5%533,9258.5
Jul 31, 20264,106,590+0.1%376,79610.9
Jul 15, 20264,102,257-6.0%542,2797.6
Jun 30, 20264,364,318-2.7%704,7806.2
Jun 15, 20264,485,642-0.9%804,6675.6
May 29, 20264,527,668+1.3%594,6807.6
May 15, 20264,470,973-3.8%673,3356.6

Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.

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