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Vertex Pharmaceuticals Inc (VRTX) stock

VRTXNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 15/3028% above fair value
$547.03−0.86 (-0.16%)

Close on Nov 11, 2026Market cap $138.65BP/E 31.8Yield –

Vertex Pharmaceuticals statistics

102 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.

Important dates

Next earnings
Feb 11, 2027 (estimated, during market hours)
Last ex-dividend date
No dividends
Fundamentals through
Jun 30, 2026
Share price as of
Nov 11, 2026

Valuation ratiosIndustry

Market Cap
$138.65B
$282.97M
Enterprise Value
$130.80B
$154.96M
PE Ratio
31.84
25.08
PS Ratio
11.02
3.71
PB Ratio
6.85
2.17
P/TBV Ratio
7.40
2.39
P/FCF Ratio
36.52
19.12
P/OCF Ratio
32.30
13.11

Enterprise valuationIndustry

EV / Sales
10.39
2.65
EV / EBITDA
26.16
16.59
EV / EBIT
27.38
19.03
EV / FCF
34.46
22.15

Share statisticsIndustry

Shares Change (YoY)
-1.10%
10.9%
Shares Change (QoQ)
-0.32%
0.51%
Float
253M
49M
Shares Held by Insiders
0.22%
11.6%
Shares Held by Institutions
95.6%
56.4%

Short sellingIndustry

Short Interest
5M
–
Short Interest Change
12.9%
-0.76%
Short % of Float
1.90%
9.06%
Short % of Shares Outstanding
1.90%
6.38%
Days to Cover
3.38
5.16

Stock price statisticsIndustry

52-Week High
$568.67
–
52-Week Low
$412.27
–
20-Day Moving Average
$532.21
–
50-Day Moving Average
$523.04
–
200-Day Moving Average
$482.70
–
Average True Range (14)
$16.58
–
Price Change (1 Week)
-0.37%
-0.50%
Price Change (1 Month)
12.7%
-0.33%
Price Change (3 Months)
5.92%
-17.2%
Price Change (6 Months)
20.7%
-20.1%
Price Change (YTD)
20.7%
-20.1%
Price Change (1 Year)
29.9%
-19.3%
Price Change (3 Years)
46.4%
-23.4%
Price Change (5 Years)
192.1%
-76.4%
Price Change (10 Years)
494.6%
-62.4%
Average Volume (10 Days)
2M
–
Average Volume (20 Days)
2M
–
Average Volume (90 Days)
1M
–
Relative Volume
0.82
0.73
Relative Strength Index (14)
57.3
47.6
Volatility (1 Year)
29.6%
80.2%
Beta (5 Years)
0.53
1.07

MarginsIndustry

Gross Margin
86.0%
53.1%
Operating Margin
38.0%
-37.1%
Pretax Margin
41.9%
-12.1%
Profit Margin
35.0%
-32.3%
EBITDA Margin
39.7%
-25.0%
FCF Margin
30.2%
-9.55%

Returns on capitalIndustry

Return on Equity (ROE)
23.5%
-51.3%
Return on Assets (ROA)
17.1%
-40.3%
Return on Invested Capital (ROIC)
34.4%
-34.0%
Return on Capital Employed (ROCE)
20.3%
-37.7%

Financial positionIndustry

Current Ratio
3.19
3.30
Quick Ratio
2.54
2.37

GrowthIndustry

Revenue Growth (YoY)
10.2%
7.01%
Net Income Growth (YoY)
21.1%
-24.7%
EPS Growth (YoY)
22.4%
-12.8%
FCF Growth (YoY)
8.47%
6.85%
Revenue Growth (3Y CAGR)
10.4%
2.25%
Revenue Growth (5Y CAGR)
14.1%
6.41%
EPS Growth (3Y CAGR)
6.12%
-0.17%
EPS Growth (5Y CAGR)
8.29%
3.77%

EfficiencyIndustry

Asset Turnover
0.49
0.40
Inventory Turnover
1.08
2.68
Revenue Per Employee
$20.98K
$426.63K
Profits Per Employee
$7.34K
-$680.86K
Employee Count
600,000
75
WACC
7.52%
10.1%

Income statement (TTM)Industry

Revenue
$12.59B
$66.56M
Gross Profit
$10.82B
$111.43M
Operating Income
$4.78B
-$20.20M
Pretax Income
$5.27B
-$13.50M
Net Income
$4.41B
-$21.57M
EBITDA
$5.00B
-$16.36M
EPS (Diluted)
$17.18
-$0.77

Balance sheetIndustry

Net Cash (Debt)
$7.85B
$16.31M
Net Cash Per Share
$30.98
$0.70
Equity (Book Value)
$20.25B
$53.12M
Book Value Per Share
$79.89
$1.49
Tangible Book Value
$18.75B
$26.11M
Working Capital
$8.61B
$77.59M

Cash flow (TTM)Industry

Operating Cash Flow
$4.29B
-$12.07M
Capital Expenditures
-$496.80M
-$939.00K
Free Cash Flow
$3.80B
-$18.37M
FCF Per Share
$14.98
-$0.42

Dividends and yieldsIndustry

Earnings Yield
3.18%
-19.8%
FCF Yield
2.74%
-8.81%
Buyback Yield
1.45%
-0.69%
Shareholder Yield
1.45%
0.00%

Taxes and interestIndustry

Income Tax
$869.30M
$79.50K
Effective Tax Rate
16.5%
20.7%

Scores and fair valueIndustry

Graham Number
$175.73
$19.42
Graham Upside
-67.9%
-45.8%
Altman Z-Score
13.81
0.28
Piotroski F-Score
7
4
Beneish M-Score
-2.18
-2.62
Lynch Fair Value
$142.34
–
Lynch Upside
-74.0%
-27.9%

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodVRTXS&P 500DifferenceVRTX per yearS&P 500 per year
1 month+7.2%-2.4%+9.7 pts
3 months+3.3%-1.2%+4.4 pts
Year to date+20.7%+12.3%+8.4 pts
1 year+27.4%+12.4%+15.0 pts
3 years+46.4%+78.8%−32.4 pts+13.5%+21.4%
5 years+194.3%+75.2%+119.1 pts+24.1%+11.9%
10 years+494.6%+311.1%+183.5 pts+19.5%+15.2%

Short interest

Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.

5M VRTX shares were sold short on Oct 30, 2026, up 12.9% from the previous report, or 1.90% of the shares available to trade. At recent volumes it would take 3.4 days to buy them back. Over the last 20 sessions, 54.6% of the volume reported to FINRA was short selling.

Settlement dateShares shortChangeAvg. daily volumeDays to cover
Oct 30, 20264,811,837+12.9%1,424,3373.4
Oct 15, 20264,263,331-5.3%1,257,4613.4
Sep 30, 20264,503,200-4.5%1,063,1424.2
Sep 15, 20264,716,867+1.2%938,1575.0
Aug 31, 20264,659,749+12.4%1,032,6214.5
Aug 14, 20264,146,973+5.2%1,343,9083.1
Jul 31, 20263,942,936-20.9%1,318,0613.0
Jul 15, 20264,986,691+1.0%1,607,8173.1
Jun 30, 20264,938,472+7.0%2,454,8492.0
Jun 15, 20264,616,968+2.8%1,209,8553.8
May 29, 20264,491,490+0.7%1,406,7843.2
May 15, 20264,461,773+6.9%1,224,8733.6

Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.

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