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Vertex Pharmaceuticals Inc (VRTX) stock

VRTXNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 15/3028% above fair value
$547.03−0.86 (-0.16%)

Close on Nov 11, 2026Market cap $138.65BP/E 31.8Yield –

Vertex Pharmaceuticals Inc grew revenue 10.2% to $12.59B over the twelve months to Jun 30, 2026. Operating income rose 21.8% to $4.78B, moving the operating margin from 34.4% to 38.0%. Free cash flow was $3.80B, up 8.5% from a year earlier. At the latest close the market valued the company at $138.65B, 31.8 times its earnings.

Revenue
$12.59B
+10.2% vs. a year earlier
Operating income
$4.78B
+21.8% vs. a year earlier
Free cash flow
$3.80B
+8.5% vs. a year earlier
EPS, diluted
$17.18
+22.4% vs. a year earlier

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Jun 30, 2026

Valuation

Market cap
$138.65B
P/E ratio
31.8
Price to sales
11.02
Price to book
6.85
Dividend yield
–
Free cash flow yield
2.74%

Fundamentals

Revenue
$12.59B
Net income
$4.41B
EPS, diluted
$17.18
Free cash flow
$3.80B
Book value per share
$79.34
Diluted shares
255M

Trading

Next earnings
Feb 11, 2027 (estimated, during market hours)
Previous close
$547.89
Open
$543.96
Day's range
$535.46 – $548.67
Volume
1,078,915
Average volume (20 days)
1,644,771
Index membership
S&P 500, Nasdaq-100, Russell 1000, Russell 3000
Beta (5 years)
0.53
52-week range
$412.27 – $568.67
RSI (14 days)
57.3
Volatility (1 year)
29.6%
Relative volume
0.82×
WACC
7.5%

On 2 of our idea lists: Quality compounders, Mega-cap growers

Index membership is inferred from the holdings of funds that track each index (VOO, IVV, SPYM, QQQ, IWB, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2009, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodVRTXS&P 500DifferenceVRTX per yearS&P 500 per year
1 month+7.2%-2.4%+9.7 pts
3 months+3.3%-1.2%+4.4 pts
Year to date+20.7%+12.3%+8.4 pts
1 year+27.4%+12.4%+15.0 pts
3 years+46.4%+78.8%−32.4 pts+13.5%+21.4%
5 years+194.3%+75.2%+119.1 pts+24.1%+11.9%
10 years+494.6%+311.1%+183.5 pts+19.5%+15.2%

Fifteen years at a glance

Fiscal years 2011 to 2025 and trailing twelve months, USD

Revenue

$12.59B+10.2% YoY

Gross profit

$10.82B+10.1% YoY

Operating income

$4.78B+21.8% YoY

Net income

$4.41B+21.1% YoY

EPS, diluted

$17.18+22.4% YoY

Free cash flow

$3.80B+8.5% YoY
Reported periodTrailing twelve months

Press releases

Releases Vertex Pharmaceuticals filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Vertex Pharmaceuticals

Pharmaceutical Preparations

Vertex Pharmaceuticals Incorporated is a biotechnology company operating within the pharmaceuticals segment that focuses on discovering, developing, and commercializing innovative therapies. Its commercial portfolio and product pipeline feature treatments such as TRIKAFTA/KAFTRIO, ALYFTREK, CASGEVY, and JOURNAVX, alongside collaborative research and development programs. The company supplies its therapeutic products primarily to specialized wholesale distributors, retail pharmacy chains, and healthcare distributors, including McKesson Corporation, Accredo Health Group Inc., and LloydsPharmacy.

Company profile, executives and history

Vertex Pharmaceuticals stock: common questions

What is Vertex Pharmaceuticals's stock price?

VRTX closed at $547.03 on Nov 11, 2026, down 0.16% on the day. Over the past 52 weeks it traded between $412.27 and $568.67.

What is Vertex Pharmaceuticals's market cap?

Vertex Pharmaceuticals was worth $138.65B at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is VRTX's P/E ratio?

VRTX trades at 31.8 times earnings, based on diluted earnings per share of $17.18 over the twelve months to Jun 30, 2026.

How much revenue does Vertex Pharmaceuticals make?

Vertex Pharmaceuticals reported revenue of $12.59B for the twelve months to Jun 30, 2026, up 10.2% from a year earlier.

Does Vertex Pharmaceuticals pay a dividend?

No. Vertex Pharmaceuticals has not paid a cash dividend over the last twelve months.

When does Vertex Pharmaceuticals report earnings next?

Vertex Pharmaceuticals is expected to report Q4 FY2026 results on Feb 11, 2027, during market hours. The date is estimated from its past reporting pattern until the company confirms it.

How has VRTX stock performed over the past year?

Including dividends, VRTX returned +27.4% over the past year, against +12.4% for the S&P 500.

How many VRTX shares are sold short?

5M shares were sold short at the latest FINRA report, 1.90% of the float, or 3.4 days of average trading volume.

Who are Vertex Pharmaceuticals's competitors?

Companies most similar to Vertex Pharmaceuticals by business, industry and size include REGN, VTRS, TEVA, ALNY, GMAB.

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