Spero Therapeutics, Inc. (SPRO) stock
Close on Nov 12, 2026Market cap $58.23MP/E –Yield –
Spero Therapeutics statistics
70 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.
Important dates
- Next earnings
- Nov 12, 2026 (estimated, during market hours)
- Last ex-dividend date
- No dividends
- Fundamentals through
- Sep 30, 2026
- Share price as of
- Nov 12, 2026
Valuation ratiosIndustry
- P/TBV Ratio
- 74.56
- 2.29
Enterprise valuationIndustry
- EV / Sales
- -1.20
- 2.60
Share statisticsIndustry
- Shares Change (YoY)
- 8.91%
- 10.9%
- Shares Change (QoQ)
- 0.16%
- 0.48%
- Float
- 44M
- 49M
- Shares Held by Insiders
- 24.6%
- 12.1%
- Shares Held by Institutions
- 36.9%
- 56.4%
Short sellingIndustry
- Short Interest
- 787,025
- –
- Short Interest Change
- -6.37%
- -0.76%
- Short % of Float
- 1.79%
- 9.06%
- Short % of Shares Outstanding
- 1.35%
- 6.30%
- Days to Cover
- 2.23
- 5.13
Stock price statisticsIndustry
- 52-Week High
- $3.08
- –
- 52-Week Low
- $0.96
- –
- 20-Day Moving Average
- $1.08
- –
- 50-Day Moving Average
- $1.14
- –
- 200-Day Moving Average
- $1.92
- –
- Average True Range (14)
- $0.06
- –
- Price Change (1 Week)
- -1.96%
- 1.51%
- Price Change (1 Month)
- -10.7%
- -2.37%
- Price Change (3 Months)
- -18.7%
- -21.1%
- Price Change (6 Months)
- -63.8%
- -22.8%
- Price Change (YTD)
- -57.1%
- -22.6%
- Price Change (1 Year)
- -61.8%
- -21.0%
- Price Change (3 Years)
- -9.91%
- -24.8%
- Price Change (5 Years)
- -94.0%
- -76.9%
- Average Volume (10 Days)
- 312,264
- –
- Average Volume (20 Days)
- 336,103
- –
- Average Volume (90 Days)
- 957,372
- –
- Relative Volume
- 0.34
- 0.80
- Relative Strength Index (14)
- 39.4
- 44.7
- Volatility (1 Year)
- 64.1%
- 80.2%
- Beta (5 Years)
- 1.13
- 1.07
MarginsIndustry
- EBITDA Margin
- -67.3%
- -27.7%
Returns on capitalIndustry
- Return on Equity (ROE)
- -216.4%
- -51.3%
- Return on Assets (ROA)
- -35.9%
- -40.7%
- Return on Capital Employed (ROCE)
- -52.7%
- -38.1%
Financial positionIndustry
- Current Ratio
- 1.92
- 3.31
- Quick Ratio
- 1.89
- 2.41
GrowthIndustry
- Revenue Growth (YoY)
- 2.48%
- 7.26%
- Revenue Growth (3Y CAGR)
- 7.68%
- 2.25%
- Revenue Growth (5Y CAGR)
- 48.2%
- 6.41%
EfficiencyIndustry
- Asset Turnover
- 0.51
- 0.40
- Revenue Per Employee
- $1.66M
- $429.38K
- Profits Per Employee
- -$1.18M
- -$683.67K
- Employee Count
- 25
- 75
- WACC
- 10.5%
- 10.0%
Income statement (TTM)Industry
Balance sheetIndustry
- Net Cash (Debt)
- $107.93M
- $16.98M
- Net Cash Per Share
- $1.85
- $0.72
- Equity (Book Value)
- $781.00K
- $52.68M
- Book Value Per Share
- $0.01
- $1.50
- Tangible Book Value
- $781.00K
- $26.74M
- Working Capital
- $52.27M
- $78.52M
Cash flow (TTM)Industry
Dividends and yieldsIndustry
- Earnings Yield
- -50.7%
- -21.0%
Scores and fair valueIndustry
- Altman Z-Score
- -6.09
- 0.26
- Piotroski F-Score
- 5
- 4
Total return vs. the S&P 500
Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.
| Period | SPRO | S&P 500 | Difference | SPRO per year | S&P 500 per year |
|---|---|---|---|---|---|
| 1 month | -15.3% | -2.7% | −12.6 pts | ||
| 3 months | -16.0% | -1.7% | −14.2 pts | ||
| Year to date | -57.1% | +11.9% | −69.0 pts | ||
| 1 year | -62.4% | +12.0% | −74.4 pts | ||
| 3 years | -9.9% | +78.2% | −88.1 pts | -3.4% | +21.2% |
| 5 years | -94.0% | +73.2% | −167.3 pts | -43.1% | +11.6% |
Short interest
Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.
1M SPRO shares were sold short on Oct 30, 2026, down 6.4% from the previous report, or 1.79% of the shares available to trade. At recent volumes it would take 2.2 days to buy them back. Over the last 20 sessions, 37.9% of the volume reported to FINRA was short selling.
| Settlement date | Shares short | Change | Avg. daily volume | Days to cover |
|---|---|---|---|---|
| Oct 30, 2026 | 787,025 | -6.4% | 353,093 | 2.2 |
| Oct 15, 2026 | 840,529 | +5.8% | 558,471 | 1.5 |
| Sep 30, 2026 | 794,509 | -18.6% | 1,144,097 | 1.0 |
| Sep 15, 2026 | 976,488 | -19.3% | 319,458 | 3.1 |
| Aug 31, 2026 | 1,210,417 | -16.3% | 409,813 | 3.0 |
| Aug 14, 2026 | 1,445,879 | -4.5% | 760,511 | 1.9 |
| Jul 31, 2026 | 1,513,354 | -28.4% | 2,524,691 | 1.0 |
| Jul 15, 2026 | 2,113,935 | -26.2% | 1,649,627 | 1.3 |
| Jun 30, 2026 | 2,864,850 | +56.4% | 2,752,049 | 1.0 |
| Jun 15, 2026 | 1,831,713 | +7.3% | 813,375 | 2.3 |
| May 29, 2026 | 1,706,545 | +3.6% | 868,868 | 2.0 |
| May 15, 2026 | 1,647,297 | +39.6% | 630,469 | 2.6 |
Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.
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