StockData
Fulcrum Therapeutics, Inc. logo

Fulcrum Therapeutics, Inc. (FULC) stock

FULCNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 12, 2026Score 8/30
$3.68−0.06 (-1.60%)

Close on Nov 12, 2026Market cap $280.77MP/E –Yield –

Fulcrum Therapeutics, Inc. saw revenue fall 100.0% to $0 over fiscal 2025. Free cash flow was -$65.24M. At the latest close the market valued the company at $280.77M.

Revenue
$0
-100.0% vs. a year earlier
Operating income
-$88.05M
TTM Q3 2026
Free cash flow
-$65.24M
TTM Q3 2026
EPS, diluted
-$1.18
FY2025

Key statistics

Valuation at the latest close; fundamentals over fiscal 2025, balances at Sep 30, 2026

Valuation

Market cap
$280.77M
P/E ratio
–
Price to sales
–
Price to book
0.93
Dividend yield
–
Free cash flow yield
-23.24%

Fundamentals

Revenue
$0
Net income
-$76.34M
EPS, diluted
-$1.18
Free cash flow
-$65.24M
Book value per share
$3.96
Diluted shares
76M

Trading

Previous close
$3.74
Open
$3.74
Day's range
$3.68 – $3.74
Volume
2,139,196
Average volume (20 days)
1,300,025
Index membership
Russell 2000 (since Sep 2024), Russell 3000 (since Aug 2024)
Beta (5 years)
1.56
52-week range
$2.83 – $15.74
RSI (14 days)
52.4
Volatility (1 year)
92.3%
Relative volume
0.58×
WACC
12.7%

On 1 of our idea list: Net-nets

Index membership is inferred from the holdings of funds that track each index (IWM, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodFULCS&P 500DifferenceFULC per yearS&P 500 per year
1 month-1.9%-2.7%+0.8 pts
3 months-1.1%-1.7%+0.7 pts
Year to date-67.5%+11.9%−79.4 pts
1 year-56.0%+12.0%−68.0 pts
3 years+5.1%+78.2%−73.0 pts+1.7%+21.2%
5 years-80.0%+73.2%−153.3 pts-27.6%+11.6%

Nine years at a glance

Fiscal years 2017 to 2025 and trailing twelve months, USD

Revenue

–

Operating income

-$88.05M

Net income

-$76.34M

EPS, diluted

–

Free cash flow

-$65.24M
Reported periodTrailing twelve months

Press releases

Releases Fulcrum Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Fulcrum Therapeutics

Pharmaceutical Preparations

Fulcrum Therapeutics, Inc. is a clinical-stage biopharmaceutical company that develops small-molecule therapies to treat genetically defined rare diseases. Its lead product candidate is pociredir, an investigational oral drug engineered to stimulate fetal hemoglobin production to address the biological causes of sickle cell disease. The company also investigates drug candidates for conditions such as prostate cancer and beta-thalassemia through cellular target discovery methods. Fulcrum Therapeutics operates as a single business focused on benign hematology and genetic conditions, targeting affected patients and the hematologists who provide their clinical care.

Company profile, executives and history

Fulcrum Therapeutics stock: common questions

What is Fulcrum Therapeutics's stock price?

FULC closed at $3.68 on Nov 12, 2026, down 1.60% on the day. Over the past 52 weeks it traded between $2.83 and $15.74.

What is Fulcrum Therapeutics's market cap?

Fulcrum Therapeutics was worth $280.77M at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is FULC's P/E ratio?

Fulcrum Therapeutics lost money over fiscal 2025 (diluted EPS -$1.18), so it has no meaningful P/E ratio.

How much revenue does Fulcrum Therapeutics make?

Fulcrum Therapeutics reported revenue of $0 for fiscal 2025, down 100.0% from a year earlier.

Does Fulcrum Therapeutics pay a dividend?

No. Fulcrum Therapeutics has not paid a cash dividend over the last twelve months.

How has FULC stock performed over the past year?

Including dividends, FULC returned -56.0% over the past year, against +12.0% for the S&P 500.

How many FULC shares are sold short?

6M shares were sold short at the latest FINRA report, 12.92% of the float, or 4.8 days of average trading volume.

Who are Fulcrum Therapeutics's competitors?

Companies most similar to Fulcrum Therapeutics by business, industry and size include FHTX, AGIO, KURA, KROS, WVE.

See a number that looks wrong?