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Septerna, Inc. (SEPN) stock

SEPNNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 9, 2026Score 8/30195% above fair value
$42.60+0.74 (+1.77%)

Close on Nov 13, 2026Market cap $1.99BP/E –Yield –

Septerna operating margin

Operating margin is operating income as a percentage of revenue.

Septerna's operating margin for the twelve months ending Sep 30, 2026 was -76.2%. For fiscal 2025 it was -148.6%, against -7518.4% the year before.

Annual operating margin

PeriodPeriod endValueChange (pts)
FY2025Dec 31, 2025-148.6%+7369.8
FY2024Dec 31, 2024-7518.4%−8892.6
FY2023Dec 31, 20231374.2%–

Quarterly operating margin

Change is against the same quarter a year earlier.

PeriodPeriod endValueChange (pts)
Q3 FY2026Sep 30, 2026-144.2%−156.4
Q2 FY2026Jun 30, 2026-62.9%+24288.3
Q1 FY2026Mar 31, 2026-50.1%+11780.9
Q4 FY2025Dec 31, 2025-66.4%+11593.0
Q3 FY2025Sep 30, 202512.2%+12824.7
Q2 FY2025Jun 30, 2025-24351.3%−19468.8
Q1 FY2025Mar 31, 2025-11831.1%−6944.6
Q4 FY2024Dec 31, 2024-11659.4%−40741.6
Q3 FY2024Sep 30, 2024-12812.5%+23672.3
Q2 FY2024Jun 30, 2024-4882.4%–
Q1 FY2024Mar 31, 2024-4886.4%–
Q4 FY2023Dec 31, 202329082.2%–
Q3 FY2023Sep 30, 2023-36484.8%–

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