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Prothena Corp Public Ltd Co (PRTA) shareholders

PRTANasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 5, 2026Score 12/3017% below fair value
$8.16−0.07 (-0.85%)

Close on Nov 13, 2026Market cap $418.91MP/E –Yield –

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
92.2%
47M of 51M shares
Institutional holders
188
29 new, 23 sold out
Net institutional buying
0M
In Q2 2026
Insider trades, 12 months
20 buys · 2 sales
Net bought $13.13M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
EcoR1 Capital, LLC
Joint filing with Oleg Nodelman (21.50%), EcoR1 Capital Fund Qualified, L.P. (20.20%)
11,584,28021.50%13D (active) amendmentDec 31, 2024
Abigail P. Johnson
Joint filing with FMR LLC (13.80%)
7,199,21813.80%13G (passive) amendmentJun 30, 2026
Scully William P5,378,84610.30%13G (passive) amendmentMay 7, 2026
Fennell Todd W.5,248,84610.20%13G (passive) amendmentAug 18, 2026
Rubric Capital Management LP
Joint filing with David Rosen (9.29%)
5,000,0009.29%13G (passive) amendmentMar 31, 2026
BlackRock, Inc.3,587,4806.90%13G (passive) amendmentJun 30, 2026
Logos Global Management GP LLC
Joint filing with Logos Global Management LP (5.50%), Logos Global Master Fund LP (5.50%) and 2 more
2,950,0005.50%13G (passive)May 29, 2025

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of PRTAValueChange% of portfolio
FMR LLC7,199,21814.02%$70.48M−352,0000.00%
Rubric Capital Management LP5,000,0009.74%$48.95M–0.45%
BlackRock, Inc.4,867,9559.48%$47.66M+223,7950.00%
State Street Corp2,393,4244.66%$23.43M+454,9260.00%
Acadian Asset Management LLC2,010,6453.92%$19.68M+463,0520.02%
Vanguard Portfolio Management LLC1,651,2933.22%$16.17M+205,3140.00%
D. E. Shaw & Co., Inc.1,611,4573.14%$15.78M−151,8900.01%
ADAR1 Capital Management, LLC1,554,5353.03%$15.22M−26,9080.70%
Two Sigma Investments, LP1,264,9872.46%$12.38M+59,0090.01%
Palo Alto Investors LP1,143,1552.23%$11.19M−65,4131.55%
Geode Capital Management, LLC1,125,8772.19%$11.02M+27,7110.00%
Federated Hermes, Inc.1,084,4012.11%$10.62M+24,5520.02%
Morgan Stanley995,3481.94%$9.74M−235,1000.00%
Goldman Sachs Group Inc979,7301.91%$9.59M+160,8450.00%
Jacobs Levy Equity Management, Inc965,9881.88%$9.46M−6,0290.03%
Dimensional Fund Advisors LP905,6511.76%$8.87M+123,0480.00%
Qube Research & Technologies Ltd791,1691.54%$7.75M+176,5660.01%
Renaissance Technologies LLC697,6151.36%$6.83M+90,1000.01%
Man Group plc678,1161.32%$6.64M+296,5420.01%
Mariner, LLC625,0951.22%$6.12M+62,0130.01%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 202618847M92.2%29 / 5657 / 234M4M
Q1 202618547M91.5%29 / 6851 / 237M5M
Q4 202518247M92.2%25 / 6456 / 259M5M
Q3 202518743M84.4%32 / 5761 / 3311M9M
Q2 202518842M81.6%51 / 5341 / 2315M26M
Q1 202516152M100.0%17 / 4258 / 241M3M
Q4 202417054M100.0%34 / 6240 / 285M3M
Q3 202416451M100.0%24 / 4946 / 198M4M
Q2 202416051M100.0%27 / 5743 / 342M6M
Q1 202416955M100.0%25 / 5762 / 416M5M
Q4 202318755M100.0%41 / 6945 / 386M5M
Q3 202318653M100.0%25 / 7351 / 323M2M

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
Gene G. KinneyPresident and CEO, Director68,7930.13%Jul 30, 2026
Karin L. WalkerChief Accounting Officer25,0000.05%Jul 30, 2026
Brandon S. SmithChief Operating Officer52,0000.10%Jul 30, 2026
Michael John IsaacsGeneral Counsel & Company Sec.35,7450.07%Jul 30, 2026
Chad J. SwansonChief Development Officer44,2000.09%Jul 30, 2026
Anne Evans KingstonChief Strategy Officer55,7820.11%Jul 30, 2026
Tran NguyenChief Strategy Officer and CFO40,2050.08%Jul 30, 2026
Wagner M. ZagoChief Scientific Officer85,0000.17%Jul 30, 2026
Michael J. MalecekChief Legal Officer80,0000.16%Mar 5, 2026
David A. FordChief People Officer––Mar 7, 2025
Carol D. KarpChief Regulatory Officer5,0000.01%Mar 7, 2025
Shane CookeDirector5,0000.01%May 15, 2026
Lars EkmanDirector3,1480.01%May 15, 2026
Richard T. CollierDirector6,2190.01%May 15, 2026
Dennis J. SelkoeDirector4,2080.01%May 15, 2026
Daniel G. WelchDirector––May 15, 2026
William H. Dunn Jr.Director––May 15, 2026
Paula K. CobbDirector––May 16, 2025
Helen Susan KimDirector––May 16, 2025
Todd W. Fennell10% owner––Nov 13, 2026
William P. Scully10% owner1,693,0003.30%Nov 10, 2026
EcoR1 Capital, LLC10% owner5,304,59610.33%May 6, 2025

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
William P. Scully
10% owner
Nov 9, 2026Buy+140,000$8.53$1.19M977,000
William P. Scully
10% owner
Nov 6, 2026Gift−916,444––837,000
William P. Scully
10% owner
Oct 27, 2026Gift+566,444––1,753,444
William P. Scully
10% owner
Oct 23, 2026Buy+50,000$8.07$403.52K1,187,000
William P. Scully
10% owner
Oct 22, 2026Buy+100,000$8.19$818.52K1,137,000
William P. Scully
10% owner
Oct 14, 2026Buy+10,000$8.46$84.57K1,037,000
William P. Scully
10% owner
Oct 13, 2026Buy+100,000$8.35$835.48K1,027,000
William P. Scully
10% owner
Oct 8, 2026Buy+90,000$8.57$770.90K529,000
William P. Scully
10% owner
Oct 7, 2026Buy+125,000$8.40$1.05M439,000
William P. Scully
10% owner
Oct 2, 2026Buy+100,000$8.57$857.24K314,000
William P. Scully
10% owner
Sep 29, 2026Buy+162,000$8.68$1.41M214,000
William P. Scully
10% owner
Sep 28, 2026Buy+103,500$8.60$890.10K187,000
William P. Scully
10% owner
Sep 18, 2026Buy+100,000$8.43$843.00K927,000
William P. Scully
10% owner
Sep 2, 2026Buy+27,000$9.47$255.69K827,000
William P. Scully
10% owner
Aug 20, 2026Buy+50,000$8.79$439.50K800,000
William P. Scully
10% owner
Aug 18, 2026Gift−627,553––750,000
William P. Scully
10% owner
Aug 17, 2026Gift+336,000––1,377,553
William P. Scully
10% owner
Aug 10, 2026Gift+251,553––1,041,553
William P. Scully
10% owner
Aug 7, 2026Buy+34,000$8.62$293.08K790,000
William P. Scully
10% owner
Aug 7, 2026Buy+3,500$8.62$30.17K83,500
Anne Evans Kingston
Chief Strategy Officer
Jul 29, 2026Sale(10b5-1 plan)−7,662$8.47$64.90K55,782
Michael John Isaacs
General Counsel & Company Sec.
Jul 29, 2026Sale(10b5-1 plan)−8,386$8.47$71.03K35,745
Wagner M. Zago
Chief Scientific Officer
Jul 28, 2026Option exercise+51,000––85,000
Wagner M. Zago
Chief Scientific Officer
Jul 28, 2026Returned to company−51,000$8.56$436.56K34,000
Gene G. Kinney
President and CEO, Director
Jul 28, 2026Returned to company−84,000$8.56$719.04K68,793
Gene G. Kinney
President and CEO, Director
Jul 28, 2026Option exercise+84,000––152,793
Anne Evans Kingston
Chief Strategy Officer
Jul 28, 2026Tax withholding−3,498$8.56$29.94K63,444
Chad J. Swanson
Chief Development Officer
Jul 28, 2026Returned to company−40,800$8.56$349.25K44,200
Chad J. Swanson
Chief Development Officer
Jul 28, 2026Tax withholding−3,467$8.56$29.68K40,733
Chad J. Swanson
Chief Development Officer
Jul 28, 2026Option exercise+51,000––85,000
Michael John Isaacs
General Counsel & Company Sec.
Jul 28, 2026Tax withholding−4,694$8.56$40.18K44,131
Brandon S. Smith
Chief Operating Officer
Jul 28, 2026Returned to company−78,000$8.56$667.68K52,000
Brandon S. Smith
Chief Operating Officer
Jul 28, 2026Option exercise+78,000––130,000
Karin L. Walker
Chief Accounting Officer
Jul 28, 2026Option exercise+15,000––25,000
Karin L. Walker
Chief Accounting Officer
Jul 28, 2026Returned to company−15,000$8.56$128.40K10,000
Tran Nguyen
Chief Strategy Officer and CFO
Jul 28, 2026Returned to company−57,000$8.56$487.92K40,205
Tran Nguyen
Chief Strategy Officer and CFO
Jul 28, 2026Option exercise+57,000––97,205
William P. Scully
10% owner
Jun 16, 2026Buy+20,000$7.90$158.00K756,000
William P. Scully
10% owner
Jun 15, 2026Gift−325,000––736,000
William P. Scully
10% owner
Jun 11, 2026Buy+125,000$8.17$1.02M1,061,000
William P. Scully
10% owner
Jun 4, 2026Buy+50,000$9.31$465.50K936,000
William P. Scully
10% owner
Jun 2, 2026Buy+50,000$9.43$471.50K886,000
William P. Scully
10% owner
May 22, 2026Buy+100,000$9.81$981.00K836,000
Brandon S. Smith
Chief Operating Officer
Jul 28, 2025Award+130,000––130,000
Karin L. Walker
Chief Accounting Officer
Jul 28, 2025Award+25,000––25,000
Gene G. Kinney
President and CEO, Director
Jul 28, 2025Award+140,000––152,793
Wagner M. Zago
Chief Scientific Officer
Jul 28, 2025Award+85,000––85,000
Tran Nguyen
Chief Strategy Officer and CFO
Jul 28, 2025Award+95,000––97,205
Michael J. Malecek
Chief Legal Officer
Jul 28, 2025Award+80,000––80,000
Chad J. Swanson
Chief Development Officer
Jul 28, 2025Award+85,000––85,000
EcoR1 Capital, LLC
10% owner
May 6, 2025Sale−1,984,053$7.64$15.16M5,304,596
EcoR1 Capital, LLC
10% owner
May 5, 2025Sale−977,693$8.11$7.93M7,288,649
EcoR1 Capital, LLC
10% owner
May 2, 2025Sale−3,317,938$8.36$27.74M8,266,342
William P. Scully
10% owner
Jan 15, 2025Gift−12,000––47,000
William P. Scully
10% owner
Jan 14, 2025Buy+100,000$12.79$1.28M735,993
William P. Scully
10% owner
Jan 3, 2025Gift−1,000––635,993
William P. Scully
10% owner
Jan 2, 2025Gift−13,200––636,993
William P. Scully
10% owner
Dec 31, 2024Buy+1,200$13.37$16.04K619,393
William P. Scully
10% owner
Dec 31, 2024Buy+800$13.39$10.71K620,193
William P. Scully
10% owner
Dec 31, 2024Buy+30,000$12.99$389.70K650,193

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Short interest

Shares sold short and not yet bought back, as of Oct 30, 2026 (FINRA, reported twice a month)

Short % of float
22.67%
8M shares short
Days to cover
15.7
At 1M shares a day
Change since last report
-0.4%
From 8M shares
Short volume, 20 days
65.0%
Of volume reported to FINRA

Shares sold short, last 12 months

Short sale volume counts trades marked short on any given day, including market-maker hedging, so it runs far higher than the share of Prothena Corp Public's stock actually held short. Settlement fails (shares not delivered on time) peaked at 6,503 shares on Aug 31, 2026 over the last 90 days.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
Michael John Isaacs
Officer
Jul 29, 20268,386$71.06KJul 29, 2026Restricted Stock
Anne Evans Kingston
Officer
Jul 29, 20267,662$64.92KJul 29, 2026Restricted Stock
Michael J. Malecek
Previous Officer
Jun 9, 202680,000$740.00KJun 9, 2026EMPLOYEE RESTRICTED SHARE UNIT AWARD
Karin L. Walker
Officer
Jan 24, 20245,000$170.00KJan 24, 2024Exercise of stock options
Karin L. Walker
Officer
Dec 20, 20235,000$186.45KDec 20, 2023Exercise of Stock Options
Karin L. Walker
Officer
Nov 30, 20235,000$170.00KNov 30, 2023Exercise of stock options
Karin L. Walker
Officer
Oct 25, 20235,000$206.35KOct 25, 2023Exercise of Stock Options
Brandon S. Smith
Officer
Oct 11, 20234,000$189.16KOct 11, 2023Exercise of Stock Options
Carol D. Karp
Officer
Oct 4, 20235,000$237.00KOct 4, 2023Exercise of Stock Options
Michael J. Malecek
Officer
Sep 27, 20235,000$241.05KSep 27, 2023Exercise of Stock Option
Patel Sanjiv
Director
Sep 25, 202335,000$1.75MSep 25, 2023STOCK OPTION EXERCISE
Karin L. Walker
Officer
Sep 19, 20235,000$261.81KSep 19, 2023Stock Option Exercise
Brandon S. Smith
Officer
Sep 13, 20234,000$221.56KSep 13, 2023Exercise of stock options
Hideki Garren
Officer
Sep 13, 20232,000$110.78KSep 13, 2023Exercise of Stock Options
Carol D. Karp
Officer
Sep 6, 20235,000$273.05KSep 6, 2023Exercise of stock options

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