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Bicycle Therapeutics PLC (BCYC) stock

BCYCNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Oct 29, 2026Score 11/3077% below fair value
$3.45−0.24 (-6.50%)

Close on Nov 12, 2026Market cap $241.82MP/E –Yield 0.00%

Bicycle Therapeutics PLC grew revenue 194.7% to $83.53M over the twelve months to Sep 30, 2026. Free cash flow was -$177.04M. At the latest close the market valued the company at $241.82M.

Revenue
$83.53M
+194.7% vs. a year earlier
Operating income
-$158.23M
TTM Q3 2026
Free cash flow
-$177.04M
TTM Q3 2026
EPS, diluted
-$2.03
TTM Q3 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Sep 30, 2026

Valuation

Market cap
$241.82M
P/E ratio
–
Price to sales
2.90
Price to book
0.48
Dividend yield
0.00%
Free cash flow yield
-73.21%

Fundamentals

Revenue
$83.53M
Net income
-$141.79M
EPS, diluted
-$2.03
Free cash flow
-$177.04M
Book value per share
$7.22
Diluted shares
70M

Trading

Next earnings
Mar 16, 2027 (estimated, before the open)
Previous close
$3.69
Open
$3.65
Day's range
$3.43 – $3.66
Volume
630,101
Average volume (20 days)
408,886
Beta (5 years)
1.39
52-week range
$3.33 – $7.83
RSI (14 days)
50.0
Volatility (1 year)
50.6%
Relative volume
0.44×
WACC
11.8%

On 2 of our idea lists: Net-nets, More cash than they're worth

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodBCYCS&P 500DifferenceBCYC per yearS&P 500 per year
1 month-9.2%-2.7%−6.5 pts
3 months-15.0%-1.7%−13.3 pts
Year to date-51.3%+11.9%−63.2 pts
1 year-47.4%+12.0%−59.4 pts
3 years-74.0%+78.2%−152.2 pts-36.2%+21.2%
5 years-94.0%+73.2%−167.3 pts-43.1%+11.6%

Ten years at a glance

Fiscal years 2016 to 2025 and trailing twelve months, USD

Revenue

$83.53M+194.7% YoY

Operating income

-$158.23M

Net income

-$141.79M

EPS, diluted

-$2.03

Free cash flow

-$177.04M
Reported periodTrailing twelve months

Press releases

Releases Bicycle Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Bicycle Therapeutics

Pharmaceutical Preparations

Bicycle Therapeutics is a clinical-stage biopharmaceutical company developing synthetic bicyclic peptides, termed Bicycle molecules, to treat diseases with significant unmet medical need. The company utilizes a proprietary phage display screening platform to discover and engineer therapeutics across multiple drug modalities, including drug conjugates, radioconjugates, imaging agents, and immune cell agonists. Its primary internal pipeline centers on oncology, led by product candidates such as nuzefatide pevedotin and the radiopharmaceutical BT1702. In addition to internal discovery, the company collaborates with external biopharmaceutical partners to develop therapies across various disease indications, including cardiometabolic, central nervous system, and neuromuscular conditions.

Company profile, executives and history

Bicycle Therapeutics stock: common questions

What is Bicycle Therapeutics's stock price?

BCYC closed at $3.45 on Nov 12, 2026, down 6.50% on the day. Over the past 52 weeks it traded between $3.33 and $7.83.

What is Bicycle Therapeutics's market cap?

Bicycle Therapeutics was worth $241.82M at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is BCYC's P/E ratio?

Bicycle Therapeutics lost money over the twelve months to Sep 30, 2026 (diluted EPS -$2.03), so it has no meaningful P/E ratio.

How much revenue does Bicycle Therapeutics make?

Bicycle Therapeutics reported revenue of $83.53M for the twelve months to Sep 30, 2026, up 194.7% from a year earlier.

Does Bicycle Therapeutics pay a dividend?

No. Bicycle Therapeutics has not paid a cash dividend over the last twelve months.

When does Bicycle Therapeutics report earnings next?

Bicycle Therapeutics is expected to report Q4 FY2026 results on Mar 16, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has BCYC stock performed over the past year?

Including dividends, BCYC returned -47.4% over the past year, against +12.0% for the S&P 500.

Who are Bicycle Therapeutics's competitors?

Companies most similar to Bicycle Therapeutics by business, industry and size include AMLX, PRTA, RCUS, FHTX, WVE.

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