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Madrigal Pharmaceuticals, Inc. (MDGL) stock

MDGLNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 5/308% above fair value
$433.03+0.43 (+0.10%)

Close on Nov 11, 2026Market cap $10.00BP/E –Yield –

Madrigal Pharmaceuticals, Inc. grew revenue 149.0% to $1.28B over the twelve months to Jun 30, 2026. Free cash flow was -$206.29M. At the latest close the market valued the company at $10.00B.

Revenue
$1.28B
+149.0% vs. a year earlier
Operating income
-$322.62M
TTM Q2 2026
Free cash flow
-$206.29M
TTM Q2 2026
EPS, diluted
-$11.28
TTM Q2 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Jun 30, 2026

Valuation

Market cap
$10.00B
P/E ratio
–
Price to sales
7.79
Price to book
19.10
Dividend yield
–
Free cash flow yield
-2.06%

Fundamentals

Revenue
$1.28B
Net income
-$325.10M
EPS, diluted
-$11.28
Free cash flow
-$206.29M
Book value per share
$17.97
Diluted shares
29M

Trading

Next earnings
Feb 18, 2027 (estimated, before the open)
Previous close
$432.60
Open
$433.56
Day's range
$431.55 – $440.21
Volume
296,900
Average volume (20 days)
572,645
Index membership
Russell 1000 (since Jun 2026), Russell 3000
Beta (5 years)
0.73
52-week range
$353.54 – $615.00
RSI (14 days)
44.4
Volatility (1 year)
43.6%
Relative volume
0.83×
WACC
8.5%

Index membership is inferred from the holdings of funds that track each index (IWB, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2010, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodMDGLS&P 500DifferenceMDGL per yearS&P 500 per year
1 month-8.2%-2.4%−5.8 pts
3 months-19.1%-1.2%−18.0 pts
Year to date-25.6%+12.3%−37.9 pts
1 year-20.0%+12.4%−32.5 pts
3 years+211.9%+78.8%+133.1 pts+46.1%+21.4%
5 years+371.2%+75.2%+296.0 pts+36.3%+11.9%
10 years+2583.0%+311.1%+2271.9 pts+39.0%+15.2%

Fifteen years at a glance

Fiscal years 2011 to 2025 and trailing twelve months, USD

Revenue

$1.28B+149.0% YoY

Gross profit

–

Operating income

-$322.62M

Net income

-$325.10M

EPS, diluted

-$11.28

Free cash flow

-$206.29M
Reported periodTrailing twelve months

Press releases

Releases Madrigal Pharmaceuticals filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Madrigal Pharmaceuticals

Pharmaceutical Preparations

The company is a biopharmaceutical enterprise dedicated to developing and commercializing therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), an inflammatory liver condition that causes progressive scarring and organ impairment. Its principal commercial offering is Rezdiffra (resmetirom), an oral thyroid hormone receptor beta agonist taken once daily to address liver fat accumulation and fibrosis. In addition, the firm advances a clinical pipeline that includes glucagon-like peptide-1 receptor agonists, diacylglycerol O-acyltransferase 2 inhibitors, and small interfering RNA programs designed to address complementary metabolic and genetic pathways of liver disease. Its treatments target adult patients diagnosed with noncirrhotic MASH who exhibit moderate to advanced liver fibrosis.

Company profile, executives and history

Madrigal Pharmaceuticals stock: common questions

What is Madrigal Pharmaceuticals's stock price?

MDGL closed at $433.03 on Nov 11, 2026, up 0.10% on the day. Over the past 52 weeks it traded between $353.54 and $615.00.

What is Madrigal Pharmaceuticals's market cap?

Madrigal Pharmaceuticals was worth $10.00B at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is MDGL's P/E ratio?

Madrigal Pharmaceuticals lost money over the twelve months to Jun 30, 2026 (diluted EPS -$11.28), so it has no meaningful P/E ratio.

How much revenue does Madrigal Pharmaceuticals make?

Madrigal Pharmaceuticals reported revenue of $1.28B for the twelve months to Jun 30, 2026, up 149.0% from a year earlier.

Does Madrigal Pharmaceuticals pay a dividend?

No. Madrigal Pharmaceuticals has not paid a cash dividend over the last twelve months.

When does Madrigal Pharmaceuticals report earnings next?

Madrigal Pharmaceuticals is expected to report Q4 FY2026 results on Feb 18, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has MDGL stock performed over the past year?

Including dividends, MDGL returned -20.0% over the past year, against +12.4% for the S&P 500.

How many MDGL shares are sold short?

2M shares were sold short at the latest FINRA report, 12.71% of the float, or 7.6 days of average trading volume.

Who are Madrigal Pharmaceuticals's competitors?

Companies most similar to Madrigal Pharmaceuticals by business, industry and size include CORT, INSM, MIRM, KNSA, PTCT.

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