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Xeris Biopharma Holdings, Inc. (XERS) stock

XERSNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 5, 2026Score 11/30357% above fair value
$16.66+0.01 (+0.06%)

Close on Nov 13, 2026Market cap $3.04BP/E –Yield –

Xeris Biopharma Holdings, Inc. grew revenue 38.4% to $368.26M over the twelve months to Sep 30, 2026. Operating income rose 377.3% to $46.78M, moving the operating margin from 3.7% to 12.7%. At the latest close the market valued the company at $3.04B.

Revenue
$368.26M
+38.4% vs. a year earlier
Operating income
$46.78M
+377.3% vs. a year earlier
EPS, diluted
-$0.06
TTM Q3 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Sep 30, 2026

Valuation

Market cap
$3.04B
P/E ratio
–
Price to sales
8.25
Price to book
62.26
Dividend yield
–
Free cash flow yield
–

Fundamentals

Revenue
$368.26M
Net income
-$6.50M
EPS, diluted
-$0.06
Book value per share
$0.26
Diluted shares
190M

Trading

Next earnings
Mar 1, 2027 (estimated, before the open)
Previous close
$16.65
Open
$16.59
Day's range
$16.31 – $16.76
Volume
3,399,068
Average volume (20 days)
3,465,684
Index membership
Russell 2000 (since Jun 2022), Russell 3000 (since Aug 2022)
Beta (5 years)
1.15
52-week range
$5.25 – $16.88
RSI (14 days)
85.4
Volatility (1 year)
57.1%
Relative volume
1.39×
WACC
10.9%

Index membership is inferred from the holdings of funds that track each index (IWM, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2021, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 13, 2026. The S&P 500 is measured by the SPY fund.

PeriodXERSS&P 500DifferenceXERS per yearS&P 500 per year
1 month+63.3%-3.0%+66.4 pts
3 months+100.0%-2.8%+102.8 pts
Year to date+112.2%+11.5%+100.7 pts
1 year+129.5%+13.5%+116.0 pts
3 years+928.4%+77.7%+850.7 pts+117.5%+21.1%
5 years+678.5%+72.6%+605.9 pts+50.7%+11.5%

Seven years at a glance

Fiscal years 2019 to 2025 and trailing twelve months, USD

Revenue

$368.26M+38.4% YoY

Gross profit

$321.80M+43.0% YoY

Operating income

$46.78M+377.3% YoY

Net income

-$6.50M

EPS, diluted

-$0.06

Free cash flow

–
Reported periodTrailing twelve months

Press releases

Releases Xeris Biopharma filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Xeris Biopharma

Pharmaceutical Preparations

Xeris Biopharma Holdings, Inc. is a commercial-stage biopharmaceutical company that develops and commercializes therapies for patients with chronic endocrine and neurological conditions. Its commercial portfolio includes Recorlev, a cortisol synthesis inhibitor prescribed for adults with endogenous Cushing’s syndrome who cannot undergo or have not been cured by surgery; Gvoke, a ready-to-use liquid glucagon administered for severe hypoglycemia in pediatric and adult diabetes patients; and Keveyis, a treatment for primary periodic paralysis. The company also advances development pipeline candidates such as XP-8121 for hypothyroidism and collaborates with external pharmaceutical partners using its proprietary formulation platforms.

Company profile, executives and history

Xeris Biopharma stock: common questions

What is Xeris Biopharma's stock price?

XERS closed at $16.66 on Nov 13, 2026, up 0.06% on the day. Over the past 52 weeks it traded between $5.25 and $16.88.

What is Xeris Biopharma's market cap?

Xeris Biopharma was worth $3.04B at the close on Nov 13, 2026: the share price times the diluted shares outstanding.

What is XERS's P/E ratio?

Xeris Biopharma lost money over the twelve months to Sep 30, 2026 (diluted EPS -$0.06), so it has no meaningful P/E ratio.

How much revenue does Xeris Biopharma make?

Xeris Biopharma reported revenue of $368.26M for the twelve months to Sep 30, 2026, up 38.4% from a year earlier.

Does Xeris Biopharma pay a dividend?

No. Xeris Biopharma has not paid a cash dividend over the last twelve months.

When does Xeris Biopharma report earnings next?

Xeris Biopharma is expected to report Q4 FY2026 results on Mar 1, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has XERS stock performed over the past year?

Including dividends, XERS returned +129.5% over the past year, against +13.5% for the S&P 500.

How many XERS shares are sold short?

9M shares were sold short at the latest FINRA report, 5.20% of the float, or 4.3 days of average trading volume.

Who are Xeris Biopharma's competitors?

Companies most similar to Xeris Biopharma by business, industry and size include CORT, ARDX, ETON, HRMY, PHAR.

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