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Stoke Therapeutics, Inc. (STOK) stock

STOKNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 6/30182% above fair value
$26.20−1.56 (-5.62%)

Close on Nov 12, 2026Market cap $1.69BP/E –Yield –

Stoke Therapeutics, Inc. saw revenue fall 86.2% to $27.59M over the twelve months to Jun 30, 2026. Operating income fell 654.5% to -$223.38M, moving the operating margin from 20.2% to -809.7%. Free cash flow was -$180.68M, down 395.5% from a year earlier. At the latest close the market valued the company at $1.69B.

Revenue
$27.59M
-86.2% vs. a year earlier
Operating income
-$223.38M
-654.5% vs. a year earlier
Free cash flow
-$180.68M
-395.5% vs. a year earlier
EPS, diluted
-$3.41
-501.2% vs. a year earlier

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Jun 30, 2026

Valuation

Market cap
$1.69B
P/E ratio
–
Price to sales
61.28
Price to book
4.89
Dividend yield
–
Free cash flow yield
-10.69%

Fundamentals

Revenue
$27.59M
Net income
-$207.90M
EPS, diluted
-$3.41
Free cash flow
-$180.68M
Book value per share
$5.23
Diluted shares
66M

Trading

Next earnings
Jan 11, 2027 (estimated, before the open)
Previous close
$27.76
Open
$27.51
Day's range
$26.14 – $27.70
Volume
501,225
Average volume (20 days)
1,384,656
Index membership
Russell 2000, Russell 3000
Beta (5 years)
1.62
52-week range
$22.05 – $40.22
RSI (14 days)
48.7
Volatility (1 year)
53.2%
Relative volume
0.52×
WACC
13.0%

On 1 of our idea list: Most shorted (a warning list)

Index membership is inferred from the holdings of funds that track each index (IWM, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodSTOKS&P 500DifferenceSTOK per yearS&P 500 per year
1 month+8.5%-2.7%+11.2 pts
3 months-20.5%-1.7%−18.8 pts
Year to date-17.5%+11.9%−29.3 pts
1 year+4.3%+12.0%−7.7 pts
3 years+515.0%+78.2%+436.8 pts+83.2%+21.2%
5 years-7.8%+73.2%−81.1 pts-1.6%+11.6%

Nine years at a glance

Fiscal years 2017 to 2025 and trailing twelve months, USD

Revenue

$27.59M-86.2% YoY

Operating income

-$223.38M-654.5% YoY

Net income

-$207.90M-496.1% YoY

EPS, diluted

-$3.41-501.2% YoY

Free cash flow

-$180.68M-395.5% YoY
Reported periodTrailing twelve months

Press releases

Releases Stoke Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Stoke Therapeutics

Pharmaceutical Preparations

Stoke Therapeutics, Inc. is a clinical-stage biotechnology company that develops antisense oligonucleotide medicines to address the genetic causes of severe diseases. Utilizing its Targeted Augmentation of Nuclear Gene Output platform, the company restores protein expression in haploinsufficiency disorders affecting the central nervous system and the eye. Its lead product candidate is zorevunersen, an investigational treatment for Dravet syndrome, and its pipeline includes STK-002 for autosomal dominant optic atrophy alongside preclinical research programs. Stoke Therapeutics develops these therapies for patients with rare genetic conditions and collaborates with biopharmaceutical partners including Biogen and Acadia Pharmaceuticals.

Company profile, executives and history

Stoke Therapeutics stock: common questions

What is Stoke Therapeutics's stock price?

STOK closed at $26.20 on Nov 12, 2026, down 5.62% on the day. Over the past 52 weeks it traded between $22.05 and $40.22.

What is Stoke Therapeutics's market cap?

Stoke Therapeutics was worth $1.69B at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is STOK's P/E ratio?

Stoke Therapeutics lost money over the twelve months to Jun 30, 2026 (diluted EPS -$3.41), so it has no meaningful P/E ratio.

How much revenue does Stoke Therapeutics make?

Stoke Therapeutics reported revenue of $27.59M for the twelve months to Jun 30, 2026, down 86.2% from a year earlier.

Does Stoke Therapeutics pay a dividend?

No. Stoke Therapeutics has not paid a cash dividend over the last twelve months.

When does Stoke Therapeutics report earnings next?

Stoke Therapeutics is expected to report Q4 FY2026 results on Jan 11, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has STOK stock performed over the past year?

Including dividends, STOK returned +4.3% over the past year, against +12.0% for the S&P 500.

How many STOK shares are sold short?

11M shares were sold short at the latest FINRA report, 28.45% of the float, or 6.8 days of average trading volume.

Who are Stoke Therapeutics's competitors?

Companies most similar to Stoke Therapeutics by business, industry and size include QURE, WVE, PRQR, NAMS, KROS.

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