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Spruce Biosciences, Inc. (SPRB) stock

SPRBNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 9, 2026Score 3/30
$42.89−3.31 (-7.16%)

Close on Nov 12, 2026Market cap $123.27MP/E –Yield –

Spruce Biosciences statistics

61 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.

Important dates

Next earnings
Mar 8, 2027 (estimated, before the open)
Last ex-dividend date
No dividends
Fundamentals through
Sep 30, 2026
Share price as of
Nov 12, 2026

Valuation ratiosIndustry

Market Cap
$123.27M
$280.48M
Enterprise Value
$43.39M
$148.62M
PB Ratio
1.86
2.05
P/TBV Ratio
1.86
2.29

Share statisticsIndustry

Shares Change (YoY)
245.4%
10.9%
Shares Change (QoQ)
4.40%
0.51%
Float
813,385
49M
Shares Held by Insiders
71.7%
12.1%
Shares Held by Institutions
69.7%
56.4%

Short sellingIndustry

Short Interest
531,380
–
Short Interest Change
1.77%
-0.76%
Short % of Float
65.3%
9.04%
Short % of Shares Outstanding
18.5%
6.30%
Days to Cover
6.95
5.13

Stock price statisticsIndustry

52-Week High
$127.90
–
52-Week Low
$38.06
–
20-Day Moving Average
$44.67
–
50-Day Moving Average
$47.51
–
200-Day Moving Average
$54.25
–
Average True Range (14)
$3.56
–
Price Change (1 Week)
0.42%
1.51%
Price Change (1 Month)
10.0%
-2.35%
Price Change (3 Months)
-18.5%
-21.1%
Price Change (6 Months)
-27.3%
-22.6%
Price Change (YTD)
-50.8%
-22.6%
Price Change (1 Year)
-61.9%
-20.7%
Price Change (3 Years)
-47.1%
-27.4%
Price Change (5 Years)
-87.2%
-77.3%
Average Volume (10 Days)
70,685
–
Average Volume (20 Days)
74,409
–
Average Volume (90 Days)
77,628
–
Relative Volume
0.59
0.79
Relative Strength Index (14)
44.9
44.7
Volatility (1 Year)
84.3%
80.4%

Returns on capitalIndustry

Return on Equity (ROE)
-187.3%
-51.2%
Return on Assets (ROA)
-125.2%
-40.6%
Return on Capital Employed (ROCE)
-86.8%
-38.0%

Financial positionIndustry

Current Ratio
4.83
3.30
Quick Ratio
4.69
2.42
Debt / Equity
0.12
0.49
Interest Coverage
-21.35
-6.35

EfficiencyIndustry

Profits Per Employee
-$8.39M
-$683.67K
Employee Count
8
75

Income statement (TTM)Industry

Operating Income
-$63.58M
-$20.99M
Net Income
-$67.15M
-$21.61M
EBITDA
-$61.95M
-$16.85M
EPS (Diluted)
-$35.41
-$0.75

Balance sheetIndustry

Total Debt
$7.82M
$116.91M
Net Cash (Debt)
$79.88M
$17.46M
Net Cash Per Share
$27.79
$0.72
Equity (Book Value)
$66.30M
$53.27M
Book Value Per Share
$23.07
$1.50
Tangible Book Value
$66.30M
$26.82M
Working Capital
$71.59M
$79.47M

Cash flow (TTM)Industry

Operating Cash Flow
-$51.07M
-$12.27M

Dividends and yieldsIndustry

Earnings Yield
-54.5%
-20.8%

Taxes and interestIndustry

Interest Expense
$2.98M
$2.93M

Scores and fair valueIndustry

Altman Z-Score
-3.67
0.30
Piotroski F-Score
3
4

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodSPRBS&P 500DifferenceSPRB per yearS&P 500 per year
1 month+0.0%-2.7%+2.7 pts
3 months-8.9%-1.7%−7.1 pts
Year to date-50.8%+11.9%−62.7 pts
1 year-58.0%+12.0%−70.0 pts
3 years-45.6%+78.2%−123.7 pts-18.3%+21.2%
5 years-87.2%+73.2%−160.4 pts-33.7%+11.6%

Short interest

Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.

1M SPRB shares were sold short on Oct 30, 2026, up 1.8% from the previous report, or 65.33% of the shares available to trade. At recent volumes it would take 7.0 days to buy them back. Over the last 20 sessions, 62.1% of the volume reported to FINRA was short selling.

Settlement dateShares shortChangeAvg. daily volumeDays to cover
Oct 30, 2026531,380+1.8%76,4467.0
Oct 15, 2026522,120+21.0%78,8476.6
Sep 30, 2026431,541+3.7%95,3334.5
Sep 15, 2026416,140-5.5%125,0923.3
Aug 31, 2026440,243+9.2%73,6856.0
Aug 14, 2026403,031-6.1%38,68110.4
Jul 31, 2026429,122+3.2%56,4477.6
Jul 15, 2026415,860+15.7%68,2636.1
Jun 30, 2026359,389+36.8%114,0153.1
Jun 15, 2026262,616+8.6%50,0605.3
May 29, 2026241,927+12.5%57,2624.2
May 15, 2026215,061+4.3%36,7665.8

Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.

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