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Shuttle Pharmaceuticals Holdings, Inc. (SHPH) stock

SHPHNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Sep 24, 2026Score 5/30
$4.53−0.23 (-4.83%)

Close on Nov 13, 2026Market cap $4.54MP/E –Yield –

Key statistics

Valuation at the latest close; fundamentals over fiscal , balances at Jun 30, 2026

Valuation

Market cap
$4.54M
P/E ratio
–
Price to sales
–
Price to book
0.24
Dividend yield
–
Free cash flow yield
–

Fundamentals

Net income
-$10.26M
EPS, diluted
-$71.60
Book value per share
$18.90
Diluted shares
1M

Trading

Previous close
$4.76
Open
$4.64
Day's range
$4.53 – $4.65
Volume
10,278
Average volume (20 days)
28,290
Beta (5 years)
2.21
52-week range
$2.58 – $44.40
RSI (14 days)
43.4
Volatility (1 year)
141.6%
Relative volume
0.01×
WACC
16.1%

Market cap history

Month-end market cap since 2022, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 13, 2026. The S&P 500 is measured by the SPY fund.

PeriodSHPHS&P 500DifferenceSHPH per yearS&P 500 per year
1 month-12.5%-3.0%−9.5 pts
3 months-1.1%-2.8%+1.7 pts
Year to date-74.8%+11.5%−86.3 pts
1 year-80.4%+13.5%−93.9 pts
3 years-99.5%+77.7%−177.2 pts-83.5%+21.1%

Six years at a glance

Fiscal years 2020 to 2025 and trailing twelve months, USD

Operating income

-$11.22M

Net income

-$10.26M

EPS, diluted

–

Free cash flow

–
Reported periodTrailing twelve months

Press releases

Releases Shuttle Pharmaceuticals filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Shuttle Pharmaceuticals

Pharmaceutical Preparations

Shuttle Pharmaceuticals Holdings, Inc. operates as a pharmaceutical software and drug discovery enterprise centered around Molecule.ai, an artificial intelligence platform acquired in November 2025. The company previously developed clinical-stage therapeutic candidates, notably Ropidoxuridine, prior to initiating a wind-down of its clinical trials. Molecule.ai integrates a unified inference engine, an API-first framework, and modular predictive models to support molecular property prediction, multi-compound comparative analysis, and structured scientific reasoning. These software solutions serve researchers and pharmaceutical research and development teams navigating chemical exploration and early-stage drug design.

Company profile, executives and history

Shuttle Pharmaceuticals stock: common questions

What is Shuttle Pharmaceuticals's stock price?

SHPH closed at $4.53 on Nov 13, 2026, down 4.83% on the day. Over the past 52 weeks it traded between $2.58 and $44.40.

What is Shuttle Pharmaceuticals's market cap?

Shuttle Pharmaceuticals was worth $4.54M at the close on Nov 13, 2026: the share price times the diluted shares outstanding.

What is SHPH's P/E ratio?

Shuttle Pharmaceuticals lost money over fiscal 2025 (diluted EPS -$71.60), so it has no meaningful P/E ratio.

Does Shuttle Pharmaceuticals pay a dividend?

No. Shuttle Pharmaceuticals has not paid a cash dividend over the last twelve months.

How has SHPH stock performed over the past year?

Including dividends, SHPH returned -80.4% over the past year, against +13.5% for the S&P 500.

Who are Shuttle Pharmaceuticals's competitors?

Companies most similar to Shuttle Pharmaceuticals by business, industry and size include KALA, NBP, CDT, BFRG, COCP.

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