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Rhythm Pharmaceuticals, Inc. (RYTM) stock

RYTMNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 5/30257% above fair value
$112.16−1.79 (-1.57%)

Close on Nov 11, 2026Market cap $7.72BP/E –Yield –

Rhythm Pharmaceuticals, Inc. grew revenue 53.5% to $239.92M over the twelve months to Jun 30, 2026. Free cash flow was -$116.63M. At the latest close the market valued the company at $7.72B.

Revenue
$239.92M
+53.5% vs. a year earlier
Operating income
-$200.63M
TTM Q2 2026
Free cash flow
-$116.63M
FY2025
EPS, diluted
-$3.11
TTM Q2 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Jun 30, 2026

Valuation

Market cap
$7.72B
P/E ratio
–
Price to sales
32.19
Price to book
74.99
Dividend yield
–
Free cash flow yield
–

Fundamentals

Revenue
$239.92M
Net income
-$205.35M
EPS, diluted
-$3.11
Free cash flow
-$116.63M
Book value per share
$1.50
Diluted shares
69M

Trading

Next earnings
Feb 25, 2027 (estimated, before the open)
Previous close
$113.95
Open
$113.76
Day's range
$112.04 – $115.20
Volume
740,315
Average volume (20 days)
1,741,342
Index membership
Russell 2000 (since Jun 2023), Russell 3000 (since Aug 2023)
Beta (5 years)
1.41
52-week range
$74.50 – $122.20
RSI (14 days)
65.5
Volatility (1 year)
54.3%
Relative volume
0.82×
WACC
11.9%

On 1 of our idea list: Most shorted (a warning list)

Index membership is inferred from the holdings of funds that track each index (IWM, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2017, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodRYTMS&P 500DifferenceRYTM per yearS&P 500 per year
1 month+23.6%-2.4%+26.0 pts
3 months-0.6%-1.2%+0.5 pts
Year to date+4.8%+12.3%−7.5 pts
1 year+12.3%+12.4%−0.1 pts
3 years+294.1%+78.8%+215.3 pts+58.0%+21.4%
5 years+730.2%+75.2%+655.0 pts+52.7%+11.9%

Twelve years at a glance

Fiscal years 2014 to 2025 and trailing twelve months, USD

Revenue

$239.92M+53.5% YoY

Gross profit

$213.53M+53.1% YoY

Operating income

-$200.63M

Net income

-$205.35M

EPS, diluted

-$3.11

Free cash flow

–
Reported periodTrailing twelve months

Press releases

Releases Rhythm Pharmaceuticals filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Rhythm Pharmaceuticals

Pharmaceutical Preparations

Rhythm Pharmaceuticals is a commercial-stage biopharmaceutical company focused on developing precision medicines to treat rare neuroendocrine diseases. The company concentrates on advancing melanocortin-4 receptor agonists designed to address hyperphagia and severe obesity resulting from impaired signaling pathways in the brain. Its primary marketed therapy is IMCIVREE, which is authorized to manage weight and control hunger in adult and pediatric patients with rare conditions such as Bardet-Biedl syndrome and specific genetic deficiencies involving pro-opiomelanocortin, proprotein convertase subtilisin/kexin type 1, or leptin receptor genes. Beyond its approved treatments, the company is evaluating earlier-stage investigational drug candidates, including bivamelagon and RM-718, for hypothalamic obesity and Prader-Willi syndrome.

Company profile, executives and history

Rhythm Pharmaceuticals stock: common questions

What is Rhythm Pharmaceuticals's stock price?

RYTM closed at $112.16 on Nov 11, 2026, down 1.57% on the day. Over the past 52 weeks it traded between $74.50 and $122.20.

What is Rhythm Pharmaceuticals's market cap?

Rhythm Pharmaceuticals was worth $7.72B at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is RYTM's P/E ratio?

Rhythm Pharmaceuticals lost money over the twelve months to Jun 30, 2026 (diluted EPS -$3.11), so it has no meaningful P/E ratio.

How much revenue does Rhythm Pharmaceuticals make?

Rhythm Pharmaceuticals reported revenue of $239.92M for the twelve months to Jun 30, 2026, up 53.5% from a year earlier.

Does Rhythm Pharmaceuticals pay a dividend?

No. Rhythm Pharmaceuticals has not paid a cash dividend over the last twelve months.

When does Rhythm Pharmaceuticals report earnings next?

Rhythm Pharmaceuticals is expected to report Q4 FY2026 results on Feb 25, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has RYTM stock performed over the past year?

Including dividends, RYTM returned +12.3% over the past year, against +12.4% for the S&P 500.

How many RYTM shares are sold short?

12M shares were sold short at the latest FINRA report, 17.14% of the float, or 23.3 days of average trading volume.

Who are Rhythm Pharmaceuticals's competitors?

Companies most similar to Rhythm Pharmaceuticals by business, industry and size include ETON, ZVRA, AMLX, PHAR, MIRM.

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