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Personalis, Inc. (PSNL) stock

PSNLNasdaqServices-Medical LaboratoriesFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 4, 2026Score 5/30350% above fair value
$15.96+0.08 (+0.50%)

Close on Nov 11, 2026Market cap $1.70BP/E –Yield –

Personalis, Inc. grew revenue 16.9% to $80.77M over the twelve months to Sep 30, 2026. Free cash flow was -$107.69M. At the latest close the market valued the company at $1.70B.

Revenue
$80.77M
+16.9% vs. a year earlier
Operating income
-$126.54M
TTM Q3 2026
Free cash flow
-$107.69M
TTM Q3 2026
EPS, diluted
-$1.17
TTM Q3 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Sep 30, 2026

Valuation

Market cap
$1.70B
P/E ratio
–
Price to sales
21.10
Price to book
8.01
Dividend yield
–
Free cash flow yield
-6.32%

Fundamentals

Revenue
$80.77M
Net income
-$119.33M
EPS, diluted
-$1.17
Free cash flow
-$107.69M
Book value per share
$1.98
Diluted shares
107M

Trading

Next earnings
Feb 25, 2027 (estimated, after the close)
Previous close
$15.88
Open
$15.90
Day's range
$15.90 – $16.04
Volume
1,139,046
Average volume (20 days)
2,212,822
Index membership
Russell 2000 (since Jun 2025), Russell 3000 (since Aug 2025)
Beta (5 years)
1.88
52-week range
$4.96 – $18.89
RSI (14 days)
52.1
Volatility (1 year)
79.4%
Relative volume
0.35×
WACC
14.3%

Index membership is inferred from the holdings of funds that track each index (IWM, IWV), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodPSNLS&P 500DifferencePSNL per yearS&P 500 per year
1 month-0.2%-2.4%+2.2 pts
3 months+13.8%-1.2%+15.0 pts
Year to date+100.5%+12.3%+88.2 pts
1 year+89.1%+12.4%+76.7 pts
3 years+1464.7%+78.8%+1385.9 pts+150.1%+21.4%
5 years-15.9%+75.2%−91.1 pts-3.4%+11.9%

Ten years at a glance

Fiscal years 2016 to 2025 and trailing twelve months, USD

Revenue

$80.77M+16.9% YoY

Gross profit

$13.49M-26.8% YoY

Operating income

-$126.54M

Net income

-$119.33M

EPS, diluted

-$1.17

Free cash flow

-$107.69M
Reported periodTrailing twelve months

Press releases

Releases Personalis filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Personalis

Services-Medical Laboratories

Personalis, Inc. operates as a cancer genomics company focused on enabling personalized cancer therapies and providing diagnostic testing solutions. The company offers specialized laboratory testing services that support clinical diagnostics and pharmaceutical research and development, including population sequencing and enterprise sales. Its service offerings assist biopharmaceutical and clinical diagnostic partners in advancing cancer therapeutics, monitoring disease progression, and supporting clinical trials. Key customers include biopharmaceutical organizations such as Moderna, Pfizer, and Merck, along with healthcare entities like AstraZeneca and government initiatives such as the U.S. Department of Veterans Affairs' Million Veteran Program.

Company profile, executives and history

Personalis stock: common questions

What is Personalis's stock price?

PSNL closed at $15.96 on Nov 11, 2026, up 0.50% on the day. Over the past 52 weeks it traded between $4.96 and $18.89.

What is Personalis's market cap?

Personalis was worth $1.70B at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is PSNL's P/E ratio?

Personalis lost money over the twelve months to Sep 30, 2026 (diluted EPS -$1.17), so it has no meaningful P/E ratio.

How much revenue does Personalis make?

Personalis reported revenue of $80.77M for the twelve months to Sep 30, 2026, up 16.9% from a year earlier.

Does Personalis pay a dividend?

No. Personalis has not paid a cash dividend over the last twelve months.

When does Personalis report earnings next?

Personalis is expected to report Q4 FY2026 results on Feb 25, 2027, after the close. The date is estimated from its past reporting pattern until the company confirms it.

How has PSNL stock performed over the past year?

Including dividends, PSNL returned +89.1% over the past year, against +12.4% for the S&P 500.

How many PSNL shares are sold short?

7M shares were sold short at the latest FINRA report, 7.44% of the float, or 3.3 days of average trading volume.

Who are Personalis's competitors?

Companies most similar to Personalis by business, industry and size include GRAL, BDSX, MDXH, FLGT, XGN.

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