Prime Medicine, Inc. (PRME) stock
PRMENasdaqBiological Products, (No Diagnostic Substances)Fiscal year ends December 31
$4.27+0.38 (+9.77%)
Close on Nov 13, 2026Market cap $774.48MP/E –Yield –
Prime Medicine operating margin
Operating margin is operating income as a percentage of revenue.
Prime Medicine's operating margin for the twelve months ending Dec 31, 2025 was -4498.1%. For fiscal 2025 it was -4498.1%, against -6787.4% the year before.
Annual operating margin
| Period | Period end | Value | Change (pts) |
|---|---|---|---|
| FY2025 | Dec 31, 2025 | -4498.1% | +2289.3 |
| FY2024 | Dec 31, 2024 | -6787.4% | −6769.5 |
| FY2020 | Dec 31, 2020 | -17.9% | – |
Quarterly operating margin
Change is against the same quarter a year earlier.
| Period | Period end | Value | Change (pts) |
|---|---|---|---|
| Q3 FY2026 | Sep 30, 2026 | -947.7% | +2655.6 |
| Q4 FY2025 | Dec 31, 2025 | -5800.5% | −3774.7 |
| Q3 FY2025 | Sep 30, 2025 | -4406.0% | +21542.4 |
| Q2 FY2025 | Jun 30, 2025 | -4787.2% | +3392.4 |
| Q1 FY2025 | Mar 31, 2025 | -3603.3% | – |
| Q4 FY2024 | Dec 31, 2024 | -2025.7% | – |
| Q3 FY2024 | Sep 30, 2024 | -25948.3% | – |
| Q1 FY2024 | Mar 31, 2024 | -8179.5% | – |
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