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Palisade Bio, Inc. (PALI) stock

PALINasdaqBiological Products, (No Diagnostic Substances)Fiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 10, 2026Score 6/30
$1.14−0.03 (-2.56%)

Close on Nov 12, 2026Market cap $198.67MP/E –Yield –

Palisade Bio, Inc. reported revenue of $500.00K for the twelve months to Sep 30, 2026. At the latest close the market valued the company at $198.67M.

Revenue
$500.00K
TTM Q3 2026
Operating income
-$48.13M
TTM Q3 2026
EPS, diluted
-$0.30
FY2025

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Sep 30, 2026

Valuation

Market cap
$198.67M
P/E ratio
–
Price to sales
397.34
Price to book
1.77
Dividend yield
–
Free cash flow yield
–

Fundamentals

Revenue
$500.00K
Net income
-$43.70M
EPS, diluted
-$0.30
Book value per share
$0.53
Diluted shares
212M

Trading

Previous close
$1.17
Open
$1.16
Day's range
$1.13 – $1.18
Volume
985,371
Average volume (20 days)
3,860,768
Index membership
Russell 2000 (since Jun 2026)
Beta (5 years)
0.97
52-week range
$1.08 – $2.85
RSI (14 days)
38.2
Volatility (1 year)
89.8%
Relative volume
0.34×
WACC
9.7%

On 1 of our idea list: More cash than they're worth

Index membership is inferred from the holdings of funds that track each index (IWM), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2011, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodPALIS&P 500DifferencePALI per yearS&P 500 per year
1 month-28.3%-2.7%−25.6 pts
3 months-41.8%-1.7%−40.1 pts
Year to date-51.5%+11.9%−63.4 pts
1 year-44.1%+12.0%−56.1 pts
3 years-85.7%+78.2%−163.8 pts-47.7%+21.2%
5 years-99.9%+73.2%−173.2 pts-77.6%+11.6%
10 years-100.0%+309.6%−409.6 pts-71.5%+15.1%

Fifteen years at a glance

Fiscal years 2011 to 2025 and trailing twelve months, USD

Revenue

$500.00K

Operating income

-$48.13M

Net income

-$43.70M

EPS, diluted

–

Free cash flow

–
Reported periodTrailing twelve months

Press releases

Releases Palisade Bio filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Palisade Bio

Biological Products, (No Diagnostic Substances)

The company is a clinical-stage biopharmaceutical business focused on developing oral phosphodiesterase-4 inhibitor prodrugs for inflammatory and fibrotic diseases. Its primary product candidate, PALI-2108, is an orally delivered therapy engineered for targeted bacterial bioactivation in the lower gastrointestinal tract. Alongside its therapeutic candidates, the business develops biomarker assays to identify individuals who are likely to respond to treatment. Its target patient populations consist of individuals suffering from inflammatory bowel diseases, specifically ulcerative colitis and Crohn's disease, including fibrostenosing Crohn's disease.

Company profile, executives and history

Palisade Bio stock: common questions

What is Palisade Bio's stock price?

PALI closed at $1.14 on Nov 12, 2026, down 2.56% on the day. Over the past 52 weeks it traded between $1.08 and $2.85.

What is Palisade Bio's market cap?

Palisade Bio was worth $198.67M at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is PALI's P/E ratio?

Palisade Bio lost money over fiscal 2025 (diluted EPS -$0.30), so it has no meaningful P/E ratio.

How much revenue does Palisade Bio make?

Palisade Bio reported revenue of $500.00K for the twelve months to Sep 30, 2026.

Does Palisade Bio pay a dividend?

No. Palisade Bio has not paid a cash dividend over the last twelve months.

How has PALI stock performed over the past year?

Including dividends, PALI returned -44.1% over the past year, against +12.0% for the S&P 500.

How many PALI shares are sold short?

29M shares were sold short at the latest FINRA report, 17.63% of the float, or 7.8 days of average trading volume.

Who are Palisade Bio's competitors?

Companies most similar to Palisade Bio by business, industry and size include CRDF, YARW, IMA, CMPX, SRRK.

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