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Monopar Therapeutics (MNPR) stock

MNPRNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 12, 2026Score 7/30
$71.73−0.05 (-0.07%)

Close on Nov 11, 2026Market cap $481.46MP/E –Yield –

Monopar Therapeutics reported revenue of $0 for fiscal 2025. At the latest close the market valued the company at $481.46M.

Revenue
$0
FY2025
Operating income
-$25.49M
TTM Q3 2026
EPS, diluted
-$2.41
TTM Q3 2026

Key statistics

Valuation at the latest close; fundamentals over fiscal 2025, balances at Sep 30, 2026

Valuation

Market cap
$481.46M
P/E ratio
–
Price to sales
–
Price to book
3.79
Dividend yield
–
Free cash flow yield
–

Fundamentals

Revenue
$0
Net income
-$20.60M
EPS, diluted
-$2.41
Book value per share
$14.84
Diluted shares
9M

Trading

Next earnings
Nov 12, 2026 (estimated, before the open)
Previous close
$71.78
Open
$72.87
Day's range
$70.80 – $72.87
Volume
157,460
Average volume (20 days)
136,536
Index membership
Russell 2000 (since Jun 2025)
Beta (5 years)
0.78
52-week range
$50.07 – $124.82
RSI (14 days)
44.6
Volatility (1 year)
63.8%
Relative volume
0.80×
WACC
8.8%

On 1 of our idea list: Most shorted (a warning list)

Index membership is inferred from the holdings of funds that track each index (IWM), as reported to the SEC for Jun 30, 2026. Join dates come from quarterly fund reports since 2019, so they are accurate to the quarter.

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodMNPRS&P 500DifferenceMNPR per yearS&P 500 per year
1 month-9.2%-2.4%−6.7 pts
3 months-37.3%-1.2%−36.2 pts
Year to date+9.8%+12.3%−2.4 pts
1 year-14.0%+12.4%−26.5 pts
3 years+3791.0%+78.8%+3712.2 pts+238.9%+21.4%
5 years+186.3%+75.2%+111.2 pts+23.4%+11.9%

Eleven years at a glance

Fiscal years 2015 to 2025 and trailing twelve months, USD

Revenue

–

Operating income

-$25.49M

Net income

-$20.60M

EPS, diluted

-$2.41
Reported periodTrailing twelve months

Press releases

Releases Monopar Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Monopar Therapeutics

Pharmaceutical Preparations

Monopar Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for Wilson disease and targeted radiopharmaceuticals for oncology. Its primary therapeutic asset is ALXN1840, an investigational oral small molecule designed to bind and remove copper in Wilson disease patients. The company's oncology pipeline consists of uPAR-targeted radiopharmaceutical candidates, including MNPR-101-Zr for diagnostic imaging, MNPR-101-Lu for radioimmunotherapy, and preclinical MNPR-101-Ac for treating advanced solid cancers. Monopar develops its pipeline through internal programs and strategic licensing, aiming to serve individuals affected by rare genetic disorders and advanced malignancies.

Company profile, executives and history

Monopar Therapeutics stock: common questions

What is Monopar Therapeutics's stock price?

MNPR closed at $71.73 on Nov 11, 2026, down 0.07% on the day. Over the past 52 weeks it traded between $50.07 and $124.82.

What is Monopar Therapeutics's market cap?

Monopar Therapeutics was worth $481.46M at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is MNPR's P/E ratio?

Monopar Therapeutics lost money over the twelve months to Sep 30, 2026 (diluted EPS -$2.41), so it has no meaningful P/E ratio.

How much revenue does Monopar Therapeutics make?

Monopar Therapeutics reported revenue of $0 for fiscal 2025.

Does Monopar Therapeutics pay a dividend?

No. Monopar Therapeutics has not paid a cash dividend over the last twelve months.

When does Monopar Therapeutics report earnings next?

Monopar Therapeutics is expected to report Q3 FY2026 results on Nov 12, 2026, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has MNPR stock performed over the past year?

Including dividends, MNPR returned -14.0% over the past year, against +12.4% for the S&P 500.

Who are Monopar Therapeutics's competitors?

Companies most similar to Monopar Therapeutics by business, industry and size include RLYB, MREO, CNSP, AMLX, ARWR.

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