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Denali Therapeutics Inc. (DNLI) stock

DNLINasdaqBiological Products, (No Diagnostic Substances)Fiscal year ends December 31
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Nov 3, 2026Score 6/30
$18.89−0.84 (-4.26%)

Close on Nov 12, 2026Market cap $3.02BP/E –Yield –

Denali Therapeutics statistics

64 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.

Important dates

Next earnings
Feb 25, 2027 (estimated, during market hours)
Last ex-dividend date
No dividends
Fundamentals through
Jun 30, 2026
Share price as of
Nov 12, 2026

Valuation ratiosIndustry

Market Cap
$3.02B
$280.48M
Enterprise Value
$2.31B
$148.62M
PB Ratio
3.62
2.05
P/TBV Ratio
3.77
2.29

Share statisticsIndustry

Shares Change (YoY)
5.81%
10.9%
Shares Change (QoQ)
0.69%
0.51%
Float
149M
49M
Shares Held by Insiders
6.64%
12.1%
Shares Held by Institutions
97.7%
56.4%

Short sellingIndustry

Short Interest
15M
–
Short Interest Change
-5.04%
-0.76%
Short % of Float
9.85%
9.04%
Short % of Shares Outstanding
9.19%
6.30%
Days to Cover
9.91
5.13

Stock price statisticsIndustry

52-Week High
$27.30
–
52-Week Low
$15.34
–
20-Day Moving Average
$19.18
–
50-Day Moving Average
$19.86
–
200-Day Moving Average
$21.24
–
Average True Range (14)
$0.91
–
Price Change (1 Week)
-4.21%
1.51%
Price Change (1 Month)
5.71%
-2.35%
Price Change (3 Months)
-22.6%
-21.1%
Price Change (6 Months)
-2.58%
-22.6%
Price Change (YTD)
14.4%
-22.6%
Price Change (1 Year)
7.45%
-20.7%
Price Change (3 Years)
16.6%
-27.4%
Price Change (5 Years)
-62.8%
-77.3%
Average Volume (10 Days)
2M
–
Average Volume (20 Days)
2M
–
Average Volume (90 Days)
2M
–
Relative Volume
0.80
0.79
Relative Strength Index (14)
44.6
44.7
Volatility (1 Year)
54.0%
80.4%
Beta (5 Years)
1.66
1.07

Returns on capitalIndustry

Return on Equity (ROE)
-54.9%
-51.2%
Return on Assets (ROA)
-44.0%
-40.6%
Return on Invested Capital (ROIC)
-343.4%
-32.9%
Return on Capital Employed (ROCE)
-50.8%
-38.0%

Financial positionIndustry

Current Ratio
8.37
3.30
Quick Ratio
7.93
2.42

EfficiencyIndustry

Profits Per Employee
-$1.02M
-$683.67K
Employee Count
503
75
WACC
13.3%
10.1%

Income statement (TTM)Industry

Operating Income
-$542.70M
-$20.99M
Net Income
-$511.45M
-$21.61M
EBITDA
-$530.47M
-$16.85M
EPS (Diluted)
-$2.84
-$0.75

Balance sheetIndustry

Net Cash (Debt)
$710.47M
$17.46M
Net Cash Per Share
$4.44
$0.72
Equity (Book Value)
$835.18M
$53.27M
Book Value Per Share
$5.22
$1.50
Tangible Book Value
$799.93M
$26.82M
Working Capital
$663.84M
$79.47M

Cash flow (TTM)Industry

Operating Cash Flow
-$434.04M
-$12.27M
Capital Expenditures
-$3.42M
-$944.00K
Free Cash Flow
-$437.46M
-$18.20M
FCF Per Share
-$2.74
-$0.42

Dividends and yieldsIndustry

Earnings Yield
-16.9%
-20.8%
FCF Yield
-14.5%
-9.58%

Scores and fair valueIndustry

Altman Z-Score
1.96
0.30
Piotroski F-Score
3
4

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodDNLIS&P 500DifferenceDNLI per yearS&P 500 per year
1 month-0.3%-2.7%+2.4 pts
3 months-25.2%-1.7%−23.5 pts
Year to date+14.4%+11.9%+2.5 pts
1 year+7.8%+12.0%−4.2 pts
3 years+16.5%+78.2%−61.7 pts+5.2%+21.2%
5 years-62.8%+73.2%−136.0 pts-17.9%+11.6%

Short interest

Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.

15M DNLI shares were sold short on Oct 30, 2026, down 5.0% from the previous report, or 9.85% of the shares available to trade. At recent volumes it would take 9.9 days to buy them back. Over the last 20 sessions, 42.9% of the volume reported to FINRA was short selling.

Settlement dateShares shortChangeAvg. daily volumeDays to cover
Oct 30, 202614,694,882-5.0%1,483,3299.9
Oct 15, 202615,475,322+0.1%1,918,3798.1
Sep 30, 202615,463,975-9.8%2,023,7147.6
Sep 15, 202617,139,415+3.0%1,431,79412.0
Aug 31, 202616,642,362-7.3%951,21617.5
Aug 14, 202617,959,465+3.0%1,446,97112.4
Jul 31, 202617,434,654+8.7%1,438,87812.1
Jul 15, 202616,035,916+0.5%1,910,7588.4
Jun 30, 202615,949,089+3.5%2,295,3827.0
Jun 15, 202615,407,744+2.8%1,827,1458.4
May 29, 202614,990,471+6.9%1,870,1188.0
May 15, 202614,026,925-5.3%1,867,5257.5

Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.

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