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CRISPR Therapeutics AG (CRSP) stock

CRSPNasdaqBiological Products, (No Diagnostic Substances)Fiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 2, 2026Score 8/30
$42.62−3.13 (-6.84%)

Close on Nov 12, 2026Market cap $4.12BP/E –Yield –

CRISPR Therapeutics AG saw revenue fall 34.3% to $25.17M over the twelve months to Sep 30, 2026. Free cash flow was -$376.72M. At the latest close the market valued the company at $4.12B.

Revenue
$25.17M
-34.3% vs. a year earlier
Operating income
-$532.33M
TTM Q3 2026
Free cash flow
-$376.72M
TTM Q3 2026
EPS, diluted
-$4.74
TTM Q3 2026

Key statistics

Valuation at the latest close; fundamentals over the trailing twelve months, balances at Sep 30, 2026

Valuation

Market cap
$4.12B
P/E ratio
–
Price to sales
163.72
Price to book
2.50
Dividend yield
–
Free cash flow yield
-9.14%

Fundamentals

Revenue
$25.17M
Net income
-$456.14M
EPS, diluted
-$4.74
Free cash flow
-$376.72M
Book value per share
$17.04
Diluted shares
97M

Trading

Next earnings
Feb 11, 2027 (estimated, after the close)
Previous close
$45.75
Open
$45.09
Day's range
$42.38 – $45.09
Volume
2,493,021
Average volume (20 days)
1,602,938
Beta (5 years)
1.38
52-week range
$42.38 – $63.45
RSI (14 days)
32.5
Volatility (1 year)
58.4%
Relative volume
1.57×
WACC
11.8%

On 2 of our idea lists: More cash than they're worth, Most shorted (a warning list)

Market cap history

Month-end market cap since 2016, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodCRSPS&P 500DifferenceCRSP per yearS&P 500 per year
1 month-17.3%-2.7%−14.6 pts
3 months-21.1%-1.7%−19.3 pts
Year to date-18.7%+11.9%−30.6 pts
1 year-18.3%+12.0%−30.3 pts
3 years-19.8%+78.2%−98.0 pts-7.1%+21.2%
5 years-52.1%+73.2%−125.3 pts-13.7%+11.6%
10 years+143.5%+309.6%−166.1 pts+9.3%+15.1%

Thirteen years at a glance

Fiscal years 2013 to 2025 and trailing twelve months, USD

Revenue

$25.17M-34.3% YoY

Operating income

-$532.33M

Net income

-$456.14M

EPS, diluted

-$4.74

Free cash flow

-$376.72M
Reported periodTrailing twelve months

Press releases

Releases CRISPR Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About CRISPR Therapeutics

Biological Products, (No Diagnostic Substances)

The company is a biopharmaceutical firm that develops gene-based medicines using CRISPR/Cas9 gene-editing technology. It operates across four primary areas: hemoglobinopathies, in vivo editing, CAR T cell therapies, and regenerative medicine. Its approved therapy, CASGEVY, co-developed with Vertex Pharmaceuticals, treats severe sickle cell disease and transfusion-dependent beta thalassemia. Other investigational candidates address cardiovascular conditions, autoimmune disorders, cancers, and Type 1 diabetes. Its end users are patients suffering from severe genetic, hematologic, oncologic, and metabolic diseases.

Company profile, executives and history

CRISPR Therapeutics stock: common questions

What is CRISPR Therapeutics's stock price?

CRSP closed at $42.62 on Nov 12, 2026, down 6.84% on the day. Over the past 52 weeks it traded between $42.38 and $63.45.

What is CRISPR Therapeutics's market cap?

CRISPR Therapeutics was worth $4.12B at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is CRSP's P/E ratio?

CRISPR Therapeutics lost money over the twelve months to Sep 30, 2026 (diluted EPS -$4.74), so it has no meaningful P/E ratio.

How much revenue does CRISPR Therapeutics make?

CRISPR Therapeutics reported revenue of $25.17M for the twelve months to Sep 30, 2026, down 34.3% from a year earlier.

Does CRISPR Therapeutics pay a dividend?

No. CRISPR Therapeutics has not paid a cash dividend over the last twelve months.

When does CRISPR Therapeutics report earnings next?

CRISPR Therapeutics is expected to report Q4 FY2026 results on Feb 11, 2027, after the close. The date is estimated from its past reporting pattern until the company confirms it.

How has CRSP stock performed over the past year?

Including dividends, CRSP returned -18.3% over the past year, against +12.0% for the S&P 500.

How many CRSP shares are sold short?

17M shares were sold short at the latest FINRA report, 18.27% of the float, or 13.1 days of average trading volume.

Who are CRISPR Therapeutics's competitors?

Companies most similar to CRISPR Therapeutics by business, industry and size include EDIT, CRBU, DTIL, SGMOQ, CCCC.

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