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Aprea Therapeutics, Inc. (APRE) stock

APRENasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 4, 2026Score 6/30
$0.44−0.00 (-1.01%)

Close on Nov 12, 2026Market cap $5.54MP/E –Yield –

Key statistics

Valuation at the latest close; fundamentals over fiscal , balances at Sep 30, 2026

Valuation

Market cap
$5.54M
P/E ratio
–
Price to sales
–
Price to book
0.16
Dividend yield
–
Free cash flow yield
–

Fundamentals

Net income
-$14.14M
EPS, diluted
-$0.70
Book value per share
$0.64
Diluted shares
54M

Trading

Next earnings
Mar 15, 2027 (estimated, before the open)
Previous close
$0.44
Open
$0.45
Day's range
$0.44 – $0.45
Volume
149,386
Average volume (20 days)
156,240
Beta (5 years)
1.47
52-week range
$0.41 – $1.49
RSI (14 days)
34.1
Volatility (1 year)
96.5%
Relative volume
0.63×
WACC
12.3%

Market cap history

Month-end market cap since 2019, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 12, 2026. The S&P 500 is measured by the SPY fund.

PeriodAPRES&P 500DifferenceAPRE per yearS&P 500 per year
1 month-25.8%-2.7%−23.1 pts
3 months-35.6%-1.7%−33.8 pts
Year to date-48.4%+11.9%−60.3 pts
1 year-65.1%+12.0%−77.1 pts
3 years-88.5%+78.2%−166.7 pts-51.4%+21.2%
5 years-99.6%+73.2%−172.8 pts-66.1%+11.6%

Ten years at a glance

Fiscal years 2016 to 2025 and trailing twelve months, USD

Operating income

-$15.28M

Net income

-$14.14M

EPS, diluted

-$0.70

Free cash flow

–
Reported periodTrailing twelve months

Press releases

Releases Aprea Therapeutics filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About Aprea Therapeutics

Pharmaceutical Preparations

Aprea Therapeutics is a clinical-stage precision medicine biopharmaceutical company dedicated to discovering and developing targeted therapies for patients with biomarker-defined cancers. Utilizing the concept of synthetic lethality, the company designs small molecule inhibitors that target specific cancer-related genetic alterations and DNA damage response pathways to selectively destroy cancer cells while sparing healthy tissue. Aprea Therapeutics focuses on advancing its core pipeline programs, which feature its clinical-stage WEE1 kinase inhibitor, APR-1051, and its oral macrocyclic ATR inhibitor, ATRN-119, alongside preclinical candidates such as the DYRK1 inhibitor APR-1602.

Company profile, executives and history

Aprea Therapeutics stock: common questions

What is Aprea Therapeutics's stock price?

APRE closed at $0.44 on Nov 12, 2026, down 1.01% on the day. Over the past 52 weeks it traded between $0.41 and $1.49.

What is Aprea Therapeutics's market cap?

Aprea Therapeutics was worth $5.54M at the close on Nov 12, 2026: the share price times the diluted shares outstanding.

What is APRE's P/E ratio?

Aprea Therapeutics lost money over the twelve months to Sep 30, 2026 (diluted EPS -$0.70), so it has no meaningful P/E ratio.

Does Aprea Therapeutics pay a dividend?

No. Aprea Therapeutics has not paid a cash dividend over the last twelve months.

When does Aprea Therapeutics report earnings next?

Aprea Therapeutics is expected to report Q4 FY2026 results on Mar 15, 2027, before the open. The date is estimated from its past reporting pattern until the company confirms it.

How has APRE stock performed over the past year?

Including dividends, APRE returned -65.1% over the past year, against +12.0% for the S&P 500.

How many APRE shares are sold short?

1M shares were sold short at the latest FINRA report, 4.46% of the float, or 2.6 days of average trading volume.

Who are Aprea Therapeutics's competitors?

Companies most similar to Aprea Therapeutics by business, industry and size include PRLD, TNGX, IDYA, ZNTL, ALLR.

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