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Agios Pharmaceuticals, Inc. (AGIO) stock

AGIONasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through Q3 FY2026, quarter ended Sep 30, 2026Last filing: 10-Q on Nov 5, 2026Score 13/302% below fair value
$31.59−0.17 (-0.54%)

Close on Nov 13, 2026Market cap $1.89BP/E –Yield –

Agios Pharmaceuticals statistics

79 measures from SEC filings and the closing price. Hover a name for the formula; the last column is the median of companies in the same industry group.

Important dates

Next earnings
Feb 11, 2027 (estimated, before the open)
Last ex-dividend date
No dividends
Fundamentals through
Sep 30, 2026
Share price as of
Nov 13, 2026

Valuation ratiosIndustry

Market Cap
$1.89B
$272.32M
Enterprise Value
$978.98M
$146.23M
PS Ratio
13.39
3.66
PB Ratio
1.93
2.00
P/TBV Ratio
1.93
2.22

Enterprise valuationIndustry

EV / Sales
6.95
2.57

Share statisticsIndustry

Shares Change (YoY)
1.71%
10.8%
Shares Change (QoQ)
0.30%
0.50%
Float
59M
49M
Shares Held by Insiders
1.12%
11.7%
Shares Held by Institutions
110.7%
56.4%

Short sellingIndustry

Short Interest
7M
–
Short Interest Change
-5.38%
-0.80%
Short % of Float
11.1%
9.01%
Short % of Shares Outstanding
10.9%
6.30%
Days to Cover
5.17
5.15

Stock price statisticsIndustry

52-Week High
$46.00
–
52-Week Low
$22.24
–
20-Day Moving Average
$33.66
–
50-Day Moving Average
$33.09
–
200-Day Moving Average
$31.85
–
Average True Range (14)
$1.85
–
Price Change (1 Week)
7.41%
-1.15%
Price Change (1 Month)
-2.26%
-4.87%
Price Change (3 Months)
-6.07%
-21.0%
Price Change (6 Months)
12.1%
-20.6%
Price Change (YTD)
16.1%
-23.6%
Price Change (1 Year)
-27.6%
-22.4%
Price Change (3 Years)
41.7%
-29.5%
Price Change (5 Years)
-24.8%
-77.9%
Price Change (10 Years)
-52.8%
-65.4%
Average Volume (10 Days)
1M
–
Average Volume (20 Days)
1M
–
Average Volume (90 Days)
1M
–
Relative Volume
0.33
0.70
Relative Strength Index (14)
46.3
43.4
Volatility (1 Year)
79.8%
80.1%
Beta (5 Years)
1.41
1.07

MarginsIndustry

Gross Margin
93.8%
53.1%
Operating Margin
-297.7%
-38.7%
Profit Margin
-264.8%
-31.6%
EBITDA Margin
-297.7%
-27.7%
FCF Margin
-238.5%
-9.56%

Returns on capitalIndustry

Return on Equity (ROE)
-32.9%
-49.9%
Return on Assets (ROA)
-30.4%
-40.6%
Return on Invested Capital (ROIC)
-1169.2%
-32.9%
Return on Capital Employed (ROCE)
-42.5%
-37.9%

Financial positionIndustry

Current Ratio
9.69
3.30
Quick Ratio
11.69
2.39

GrowthIndustry

Revenue Growth (YoY)
214.4%
6.82%
Revenue Growth (3Y CAGR)
56.0%
2.25%

EfficiencyIndustry

Asset Turnover
0.11
0.40
Inventory Turnover
0.25
2.73
Revenue Per Employee
$261.30K
$429.29K
Profits Per Employee
-$691.83K
-$689.41K
Employee Count
539
74
WACC
12.1%
10.2%

Income statement (TTM)Industry

Revenue
$140.84M
$66.37M
Gross Profit
$132.12M
$120.78M
Operating Income
-$419.32M
-$21.37M
Net Income
-$372.90M
-$22.35M
EBITDA
-$419.32M
-$17.21M
EPS (Diluted)
-$6.32
-$0.76

Balance sheetIndustry

Net Cash (Debt)
$907.00M
$17.76M
Net Cash Per Share
$15.19
$0.80
Equity (Book Value)
$979.34M
$53.89M
Book Value Per Share
$16.40
$1.50
Tangible Book Value
$979.34M
$27.13M
Working Capital
$674.51M
$79.99M

Cash flow (TTM)Industry

Operating Cash Flow
-$331.68M
-$12.38M
Capital Expenditures
-$4.28M
-$1.00M
Free Cash Flow
-$335.97M
-$18.21M
FCF Per Share
-$5.63
-$0.42

Dividends and yieldsIndustry

Earnings Yield
-19.8%
-21.8%
FCF Yield
-17.8%
-9.44%

Scores and fair valueIndustry

Altman Z-Score
11.86
0.23
Piotroski F-Score
1
4

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 13, 2026. The S&P 500 is measured by the SPY fund.

PeriodAGIOS&P 500DifferenceAGIO per yearS&P 500 per year
1 month+4.6%-3.0%+7.6 pts
3 months-5.6%-2.8%−2.8 pts
Year to date+16.1%+11.5%+4.6 pts
1 year-25.7%+13.5%−39.2 pts
3 years+48.0%+77.7%−29.7 pts+14.0%+21.1%
5 years-24.8%+72.6%−97.4 pts-5.5%+11.5%
10 years-50.8%+308.2%−359.0 pts-6.8%+15.1%

Short interest

Shares sold short and not yet covered, reported by brokers to FINRA twice a month. Latest settlement date Oct 30, 2026.

7M AGIO shares were sold short on Oct 30, 2026, down 5.4% from the previous report, or 11.05% of the shares available to trade. At recent volumes it would take 5.2 days to buy them back. Over the last 20 sessions, 58.7% of the volume reported to FINRA was short selling.

Settlement dateShares shortChangeAvg. daily volumeDays to cover
Oct 30, 20266,524,140-5.4%1,261,8115.2
Oct 15, 20266,894,856-1.7%1,232,0825.6
Sep 30, 20267,016,166-7.2%1,089,9106.4
Sep 15, 20267,557,252+0.3%798,8619.5
Aug 31, 20267,535,054-1.2%893,0378.4
Aug 14, 20267,629,012+11.5%1,090,6467.0
Jul 31, 20266,840,722+3.2%1,330,2075.1
Jul 15, 20266,630,197-1.9%1,033,0806.4
Jun 30, 20266,756,481-2.1%1,331,0555.1
Jun 15, 20266,898,306-0.4%1,042,6036.6
May 29, 20266,926,807-7.0%848,5658.2
May 15, 20267,450,870+6.8%859,1038.7

Ratios use trailing-twelve-month results and the latest balance sheet. How we calculate.

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