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AC Immune SA (ACIU) stock

ACIUNasdaqPharmaceutical PreparationsFiscal year ends December 31
Financials through fiscal 2025, year ended Dec 31, 2025Last filing: 20-F on Mar 13, 2026Score 3/30
$2.26−0.03 (-1.31%)

Close on Nov 11, 2026Market cap $229.94MP/E –Yield –

AC Immune SA saw revenue fall 86.9% to CHF 3.57M over fiscal 2025. Free cash flow was -CHF 70.16M, down 207.5% from a year earlier. At the latest close the market valued the company at CHF 188.37M.

Revenue
CHF 3.57M
-86.9% vs. a year earlier
Operating income
-CHF 69.32M
FY2025
Free cash flow
-CHF 70.16M
-207.5% vs. a year earlier
EPS, diluted
-0.70 CHF
FY2025

Key statistics

Valuation at the latest close; fundamentals over fiscal 2025, balances at Jun 30, 2026

Valuation

Market cap
CHF 188.37M
P/E ratio
–
Price to sales
52.72
Price to book
–
Dividend yield
–
Free cash flow yield
-37.25%

Fundamentals

Revenue
CHF 3.57M
EPS, diluted
-0.70 CHF
Free cash flow
-CHF 70.16M

Trading

Previous close
$2.29
Open
$2.32
Day's range
$2.23 – $2.33
Volume
91,489
Average volume (20 days)
208,308
Beta (5 years)
1.19
RSI (14 days)
46.0
Volatility (1 year)
66.3%
Relative volume
0.45×
WACC
10.8%

Market cap history

Month-end market cap since 2016, using shares outstanding reported at the time

Total return vs. the S&P 500

Price change plus reinvested dividends, to the close on Nov 11, 2026. The S&P 500 is measured by the SPY fund.

PeriodACIUS&P 500DifferenceACIU per yearS&P 500 per year
1 month-9.6%-2.4%−7.2 pts
3 months-11.0%-1.2%−9.9 pts
Year to date-28.0%+12.3%−40.3 pts
1 year-33.3%+12.4%−45.8 pts
3 years-22.1%+78.8%−100.9 pts-8.0%+21.4%
5 years-62.6%+75.2%−137.8 pts-17.9%+11.9%
10 years-85.0%+311.1%−396.1 pts-17.3%+15.2%

Twelve years at a glance

Fiscal years 2014 to 2025, CHF

Revenue

CHF 3.57M-86.9% YoY

Operating income

-CHF 69.32M

EPS, diluted

-0.70 CHF

Free cash flow

-CHF 70.16M-207.5% YoY
Reported period

Press releases

Releases AC Immune filed with the SEC as exhibits to Form 8-K or 6-K

All press releases and earnings

About AC Immune

Pharmaceutical Preparations

AC Immune SA is a clinical-stage biopharmaceutical company that discovers and develops precision therapeutics and diagnostic agents for neurodegenerative disorders, particularly Alzheimer’s disease and Parkinson’s disease. The company's pipeline comprises active immunotherapies, brain-penetrant small molecule inhibitors, monoclonal antibodies, and diagnostic positron emission tomography imaging tracers. These investigational candidates target misfolded pathological proteins, including amyloid beta, tau, alpha-synuclein, and TDP-43. AC Immune operates primarily through research, development, and licensing arrangements with major global pharmaceutical companies, which serve as commercialization partners alongside clinical trial participants.

Company profile, executives and history

AC Immune stock: common questions

What is AC Immune's stock price?

ACIU closed at $2.26 on Nov 11, 2026, down 1.31% on the day.

What is AC Immune's market cap?

AC Immune was worth $229.94M at the close on Nov 11, 2026: the share price times the diluted shares outstanding.

What is ACIU's P/E ratio?

AC Immune lost money over fiscal 2025 (diluted EPS -0.70 CHF), so it has no meaningful P/E ratio.

How much revenue does AC Immune make?

AC Immune reported revenue of CHF 3.57M for fiscal 2025, down 86.9% from a year earlier.

Does AC Immune pay a dividend?

No. AC Immune has not paid a cash dividend over the last twelve months.

How has ACIU stock performed over the past year?

Including dividends, ACIU returned -33.3% over the past year, against +12.4% for the S&P 500.

Who are AC Immune's competitors?

Companies most similar to AC Immune by business, industry and size include COYA, ACRS, DNTH, IMNM, PRAX.

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