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IRDNasdaqPharmaceutical PreparationsFiscal year ends December 31

Opus Genetics, Inc.

Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 6, 2026
$3.82−0.02 (-0.52%)

Close on Oct 19, 2026

Market cap
$425.49M
P/E (TTM)
–
Dividend yield
–

Ownership

Institutional holdings as of Jun 30, 2026, from 13F filings

Held by institutions
72.8%
61M of 83M shares
Institutional holders
103
40 new, 16 sold out
Net institutional buying
15M
In Q2 2026
Insider trades, 12 months
2 buys · 17 sales
Net sold $16.27M

Shares held by institutions

Holders of more than 5%

Latest Schedule 13D (active) or 13G (passive) filed by each holder

HolderShares% of classFilingAs of
Joseph Edelman9,233,7109.99%13G (passive) amendmentJun 30, 2026
Daniel Mack7,123,5069.99%13G (passive) amendmentDec 31, 2025
Nantahala Capital Management, LLC6,250,2999.99%13G (passive) amendmentJun 30, 2025
Johnson David Edward6,077,0847.30%13G (passive) amendmentJun 30, 2026
Adage Capital Management, L.P.6,029,7758.47%13G (passive)Mar 31, 2026
Foundation Fighting Blindness, Inc.5,492,1718.00%13D (active) amendmentDec 9, 2025
Balyasny Asset Management L.P.5,480,2106.64%13G (passive) amendmentJun 30, 2026
Dames GP LLC5,110,3737.41%13G (passive)Dec 31, 2025
Wilmot B. Harkey4,839,2256.51%13G (passive) amendmentMar 31, 2026
Aaron Glenn Louis Fletcher3,683,4296.20%13G (passive)May 5, 2025

Top institutional holders

13F holdings as of Jun 30, 2026

HolderShares% of IRDValueChange% of portfolio
Nantahala Capital Management, LLC6,122,7187.36%$25.16M+4,441,3880.42%
Caligan Partners LP6,077,0847.30%$24.98M+2,0561.17%
Adage Capital Partners Gp, L.L.C.6,029,7757.25%$24.78M–0.03%
BIOS Capital Management, LP3,683,4294.43%$15.14M–36.33%
BlackRock, Inc.3,116,4873.75%$12.81M+2,968,7470.00%
Balyasny Asset Management L.P.3,087,8663.71%$12.69M+369,8370.02%
Vanguard Capital Management LLC2,958,6833.56%$12.16M+508,6960.00%
Boxer Capital Management, LLC2,815,0003.38%$11.57M+565,0000.87%
Trails Edge Capital Partners, LP2,743,6583.30%$11.28M+2,243,6581.79%
Millennium Management LLC2,302,1012.77%$9.46M−328,3310.00%
Great Point Partners LLC1,970,1872.37%$8.10M+1,645,8471.53%
Marshall Wace, Llp1,945,6092.34%$8.00M−367,7710.01%
ADAR1 Capital Management, LLC1,783,7812.14%$7.33M−65,2230.34%
Goldman Sachs Group Inc1,527,2291.84%$6.28M+1,200,4200.00%
Woodline Partners LP1,434,7131.72%$5.90M+80,6830.02%
Geode Capital Management, LLC1,367,7121.64%$5.62M+829,3650.00%
Boothbay Fund Management, LLC1,189,5151.43%$4.89M+4020.06%
Opaleye Management Inc.1,125,0001.35%$4.62M+5,0000.42%
SummitTX Capital, L.P.1,007,3511.21%$4.14MNew0.11%
State Street Corp790,1360.95%$3.25M+590,1830.00%

Institutional buying and selling by quarter

Positions opened, added to, reduced and closed by 13F filers

QuarterHoldersShares held% of sharesNew / addedReduced / closedShares boughtShares sold
Q2 202610361M72.8%40 / 3412 / 1621M6M
Q1 20267945M54.6%28 / 1615 / 628M8M
Q4 20255928M33.4%16 / 198 / 59M0M
Q3 20254819M22.9%10 / 124 / 42M1M
Q2 20254318M21.2%7 / 108 / 94M1M
Q1 20254615M17.5%14 / 78 / 1011M0M
Q4 2024434M4.4%14 / 126 / 82M0M
Q3 2024383M3.0%8 / 610 / 60M0M
Q2 2024373M3.2%3 / 715 / 140M1M
Q1 2024494M4.2%8 / 1310 / 91M1M
Q4 2023504M4.5%12 / 139 / 111M1M
Q3 2023504M4.5%12 / 1112 / 110M0M

Top mutual fund and ETF holders

Latest monthly portfolio reports (Form N-PORT)

FundShares% of IRDValue% of fundAs of
Vanguard Total Stock Market Index Fund2,239,3882.69%$9.20M0.00%Jun 30, 2026
iShares Russell 2000 ETF1,348,6901.62%$5.54M0.01%Jun 30, 2026
Vanguard Extended Market Index Fund652,2780.78%$2.68M0.00%Jun 30, 2026
Fidelity Small Cap Index Fund583,6510.70%$2.17M0.01%Jul 31, 2026
iShares Russell 2000 Growth ETF502,8840.60%$2.07M0.01%Jun 30, 2026
Fidelity Extended Market Index Fund224,3770.27%$978.28K0.00%May 31, 2026
iShares Micro-Cap ETF179,7820.22%$738.90K0.05%Jun 30, 2026
Schwab Small-Cap Index Fund130,0410.16%$482.45K0.01%Jul 31, 2026
Master Small Cap Index Series100,0990.12%$411.41K0.01%Jun 30, 2026
Fidelity Total Market Index Fund95,0020.11%$414.21K0.00%May 31, 2026
Nuveen Small Cap Blend Index Fund71,3430.09%$264.68K0.01%Jul 31, 2026
Fidelity Series Total Market Index Fund66,8100.08%$291.29K0.00%May 31, 2026
EQ/2000 Managed Volatility Portfolio58,4110.07%$240.07K0.01%Jun 30, 2026
Fidelity Small Cap Growth Index Fund49,8810.06%$205.01K0.01%Jun 30, 2026
Fidelity Nasdaq Composite Index Fund45,6720.05%$199.13K0.00%May 31, 2026

Officers, directors and major owners

People who filed Forms 3, 4 or 5 in the last two years

NameRoleShares owned% of sharesLatest filing
George MagrathChief Executive Officer, Director2,048,4852.46%Sep 11, 2026
Benjamin R. YerxaPresident, Director704,1060.85%Jul 27, 2026
Robert E. GagnonChief Financial Officer556,3750.67%Sep 8, 2026
Joseph K. SchachleChief Operating Officer291,4400.35%Jul 27, 2026
Ashwath JayagopalChief Scientific & Dev. Ofc.509,2330.61%Apr 27, 2026
Rabourn Amy ZarembaHead of Fin. Quality Assurance188,6710.23%Apr 27, 2026
Bernhard HoffmannSVP of Corp. Dev.185,4460.22%Mar 17, 2025
Nirav S. JhaveriChief Financial Officer194,2930.23%Mar 17, 2025
Cam GallagherDirector2,883,1113.47%Sep 8, 2026
Foundation Fighting Blindness, Inc.Director9,492,17111.41%May 20, 2026
Fighting Blindness Retinal Degeneration Fund FoundationDirector3,792,1714.56%May 20, 2026
Sean AinsworthDirector321,6920.39%Apr 22, 2026
Jean BennettDirector259,0190.31%Apr 22, 2026
Adrienne L. GravesDirector127,5140.15%Apr 22, 2026
James S. J. ManusoDirector317,3180.38%Apr 22, 2026
Richard J. RodgersDirector343,0220.41%Apr 22, 2026
Susan BentonDirector243,8940.29%Apr 22, 2026

Insider trades

Common stock transactions reported on Form 4, newest first

InsiderDateTransactionSharesPriceValueShares after
George Magrath
Chief Executive Officer, Director
Sep 9, 2026Tax withholding−75,541$5.97$450.98K2,048,485
George Magrath
Chief Executive Officer, Director
Sep 9, 2026Option exercise+392,157$1.15$450.98K2,124,026
Cam Gallagher
Director
Sep 8, 2026Option exercise+784,314$1.15$901.96K2,800,111
Robert E. Gagnon
Chief Financial Officer
Sep 3, 2026Sale(10b5-1 plan)−28,000$4.54$127.12K556,375
Joseph K. Schachle
Chief Operating Officer
Jul 23, 2026Sale−4,644$2.94$13.65K291,440
George Magrath
Chief Executive Officer, Director
Jul 23, 2026Sale−9,475$2.95$27.95K1,731,869
Robert E. Gagnon
Chief Financial Officer
Jul 23, 2026Sale−7,783$2.95$22.96K584,375
Benjamin R. Yerxa
President, Director
Jul 23, 2026Sale−7,429$2.97$22.06K704,106
Fighting Blindness Retinal Degeneration Fund Foundation
Director
May 18, 2026Sale−1,700,000$4.35$7.39M3,792,171
Rabourn Amy Zaremba
Head of Fin. Quality Assurance
Apr 23, 2026Sale−1,641$5.20$8.53K188,671
Ashwath Jayagopal
Chief Scientific & Dev. Ofc.
Apr 23, 2026Sale−7,542$5.19$39.14K509,233
Robert E. Gagnon
Chief Financial Officer
Apr 23, 2026Sale−7,842$5.18$40.62K592,158
George Magrath
Chief Executive Officer, Director
Apr 23, 2026Sale−9,511$5.22$49.65K1,741,344
Joseph K. Schachle
Chief Operating Officer
Apr 23, 2026Sale−4,697$5.22$24.52K296,084
Benjamin R. Yerxa
President, Director
Apr 23, 2026Sale−7,470$5.24$39.14K711,535
Richard J. Rodgers
Director
Apr 20, 2026Award+24,367––343,022
Sean Ainsworth
Director
Apr 20, 2026Award+24,367––321,692
James S. J. Manuso
Director
Apr 20, 2026Award+24,367––317,318
Susan Benton
Director
Apr 20, 2026Award+24,367––243,894
Jean Bennett
Director
Apr 20, 2026Award+24,367––259,019
Cam Gallagher
Director
Apr 20, 2026Award+24,367––2,015,797
Adrienne L. Graves
Director
Apr 20, 2026Award+24,367––127,514
Ashwath Jayagopal
Chief Scientific & Dev. Ofc.
Mar 16, 2026Sale−3,719$5.12$19.04K516,775
George Magrath
Chief Executive Officer, Director
Mar 16, 2026Sale−24,438$5.21$127.32K1,750,855
Joseph K. Schachle
Chief Operating Officer
Mar 16, 2026Sale−3,719$5.25$19.52K300,781
Rabourn Amy Zaremba
Head of Fin. Quality Assurance
Mar 16, 2026Sale−2,816$5.25$14.78K190,312
Ashwath Jayagopal
Chief Scientific & Dev. Ofc.
Feb 12, 2026Tax withholding−5,313$3.39$18.01K520,494
Robert E. Gagnon
Chief Financial Officer
Jan 22, 2026Award+400,000––600,000
Rabourn Amy Zaremba
Head of Fin. Quality Assurance
Jan 22, 2026Award+86,500––193,128
Ashwath Jayagopal
Chief Scientific & Dev. Ofc.
Jan 22, 2026Award+400,000––525,807
Joseph K. Schachle
Chief Operating Officer
Jan 22, 2026Award+250,000––304,500
George Magrath
Chief Executive Officer, Director
Jan 22, 2026Award+483,639––1,775,293
Benjamin R. Yerxa
President, Director
Jan 22, 2026Award+400,000––719,005
Rabourn Amy Zaremba
Head of Fin. Quality Assurance
Jan 18, 2026Tax withholding−3,390$2.10$7.12K106,628
Rabourn Amy Zaremba
Head of Fin. Quality Assurance
Jan 10, 2026Tax withholding−3,950$1.93$7.62K110,018
Cam Gallagher
Director
Jan 6, 2026Award+67,000––1,991,430
Sean Ainsworth
Director
Jan 1, 2026Award+42,507––297,325
Jean Bennett
Director
Jan 1, 2026Award+21,127––234,652
James S. J. Manuso
Director
Jan 1, 2026Award+31,188––292,951
Adrienne L. Graves
Director
Jan 1, 2026Award+23,643––103,147
Cam Gallagher
Director
Dec 31, 2025Award+33,000––1,924,430
Cam Gallagher
Director
Dec 29, 2025Buy+83,000$1.97$163.51K83,000
Cam Gallagher
Director
Dec 29, 2025Buy+81,000$1.98$160.38K1,891,430
Fighting Blindness Retinal Degeneration Fund Foundation
Director
Dec 9, 2025Sale−4,000,000$2.15$8.60M5,492,171
George Magrath
Chief Executive Officer, Director
Nov 1, 2025Tax withholding−30,350$2.30$69.81K1,291,654
George Magrath
Chief Executive Officer, Director
Nov 1, 2025Tax withholding−30,350$2.30$69.81K1,291,654
Benjamin R. Yerxa
President, Director
Oct 22, 2025Tax withholding−23,795$1.95$46.40K319,005
Robert E. Gagnon
Chief Financial Officer
Sep 10, 2025Award+200,000––200,000
Sean Ainsworth
Director
Aug 25, 2025Award+86,956$1.15$100.00K254,818
Cam Gallagher
Director
Aug 25, 2025Award+869,565$1.15$1,000.00K1,810,430
Foundation Fighting Blindness, Inc.
Director, 10% owner
May 5, 2025Conversion+6,927,419––9,492,171
Susan Benton
Director
Apr 30, 2025Award+79,504––219,527
Richard J. Rodgers
Director
Apr 30, 2025Award+79,504––318,655
Jean Bennett
Director
Apr 30, 2025Award+79,504––213,525
Sean Ainsworth
Director
Apr 30, 2025Award+79,504––167,862
James S. J. Manuso
Director
Apr 30, 2025Award+79,504––261,763
Cam Gallagher
Director
Apr 30, 2025Award+79,504––940,865
Adrienne L. Graves
Director
Apr 30, 2025Award+79,504––79,504
Cam Gallagher
Director
Mar 24, 2025Award+784,314––861,361
George Magrath
Chief Executive Officer, Director
Mar 24, 2025Award+392,157––1,322,004

Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.

Planned insider sales

Notices of proposed sale filed on Form 144 before shares are sold

SellerFiledSharesMarket valuePlanned saleAcquired through
Robert E. Gagnon
Officer
Sep 3, 202628,000$124.60KSep 3, 2026Vested Restricted Stock Units
Robert E. Gagnon
Officer
Jul 23, 20267,783$23.74KJul 23, 2026Vested Restricted Stock Units
Benjamin R. Yerxa
Officer
Jul 23, 20267,429$22.06KJul 23, 2026RSU GRANT VEST
Joseph K. Schachle
Officer
Jul 23, 20264,644$13.65KJul 23, 2026RSU Grant Vest
George Magrath
Officer
Jul 23, 20269,475$28.90KJul 23, 2026Vested Restricted Stock Units
Ashwath Jayagopal
Officer
Apr 23, 20267,542$39.16KApr 23, 2026RSU GRANT VEST
Robert E. Gagnon
Officer
Apr 23, 20267,842$40.66KApr 23, 2026RSU GRANT VEST
George Magrath
Officer
Apr 23, 20269,511$127.33KApr 23, 2026RSU GRANT VEST
Benjamin R. Yerxa
Officer
Apr 23, 20267,470$39.12KApr 23, 2026RSU GRANT VEST
Joseph K. Schachle
Officer
Apr 23, 20264,697$24.52KApr 23, 2026RSU GRANT VES
George Magrath
Officer
Mar 16, 202624,438$127.33KMar 16, 2026RSU Grant Vest