Denali Therapeutics Inc.
Close on Oct 19, 2026
- Market cap
- $3.38B
- P/E (TTM)
- –
- Dividend yield
- –
Earnings
Next report expected Nov 5, 2026, during market hours (estimated from past report dates)
| Quarter | Reported | Time | Revenue | EPS (GAAP) | EPS (adjusted) |
|---|---|---|---|---|---|
| Q2 FY2026 Ended Jun 30, 2026 | Aug 6, 2026 | During market hours | $3.60M | $-0.68 | – |
| Q1 FY2026 Ended Mar 31, 2026 | May 7, 2026 | During market hours | – | $-0.69 | – |
| Q4 FY2025 Ended Dec 31, 2025 | Feb 26, 2026 | During market hours | – | $-0.73 | – |
| Q3 FY2025 Ended Sep 30, 2025 | Nov 6, 2025 | During market hours | – | – | – |
| Q2 FY2025 Ended Jun 30, 2025 | Aug 11, 2025 | During market hours | – | – | – |
| Q1 FY2025 Ended Mar 31, 2025 | May 6, 2025 | During market hours | – | $-0.78 | – |
| Q4 FY2024 Ended Dec 31, 2024 | Feb 27, 2025 | During market hours | – | – | – |
| Q3 FY2024 Ended Sep 30, 2024 | Nov 6, 2024 | During market hours | – | $-0.63 | – |
| Q2 FY2024 Ended Jun 30, 2024 | Aug 1, 2024 | Before market open | – | $-0.59 | – |
| Q1 FY2024 Ended Mar 31, 2024 | May 7, 2024 | During market hours | – | $-0.68 | – |
| Q4 FY2023 Ended Dec 31, 2023 | Feb 27, 2024 | Before market open | – | $-0.86 | – |
Company guidance
Outlook given with results on Aug 6, 2026, compared with the previous outlook
| Measure | Period | Guidance | vs. prior |
|---|---|---|---|
| AVLAYAH net product revenue | third-quarter 2026 | $10.00M to $12.00M | New |
Figures and the sentence they come from are taken from the company's earnings release. Hover a measure to read the source sentence.
Press releases
Announcements Denali Therapeutics filed with the SEC
Denali Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Enters Agreement to Sell Rare Pediatric Disease
Material agreement · Regulation FD disclosure · EX-99.1 to Form 8-K
Biogen and Denali Therapeutics Provide Update on Phase 2b LUMA Study of BIIB122 (DNL151) in Early-Stage Parkinson’s Disease
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports First Quarter 2026 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces U.S. FDA Approval of AVLAYAH™ (tividenofusp alfa-eknm) for Treatment of Hunter Syndrome (MPS II)
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Key Anticipated Milestones and Priorities for 2026 Including Commercial Launch of Tividenofusp Alfa for Hunter Syndrome
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Announces Pricing of Public Offering of Common Stock and Pre-Funded Warrants
Material agreement · Other events · EX-99.1 to Form 8-K
EX-99.1 to Form 8-K
Regulation FD disclosure · Other events · EX-99.1 to Form 8-K
Denali Therapeutics Reports Third Quarter 2025 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces FDA Review Extension of BLA for Tividenofusp Alfa for the Treatment of MPS II (Hunter Syndrome)
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Second Quarter 2025 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces FDA Acceptance and Priority Review of Biologics License Application (BLA) for Tividenofusp Alfa for Hunter Syndrome (MPS II)
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Announces Initiation of BLA Filing for Accelerated Approval of Tividenofusp Alfa for the Treatment of Hunter Syndrome (MPS II) and
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Business Highlights
Material agreement · Agreement terminated · Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Key Anticipated 2025 Milestones and
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Announces Topline Results for Regimen G Evaluating eIF2B Agonist DNL343 in the Phase 2/3 HEALEY ALS Platform Trial
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Third Quarter 2024 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports Second Quarter 2024 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports First Quarter 2024 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces $500 million Private Placement Equity Financing
Material agreement · Unregistered share sale · Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Announces Key Anticipated 2024 Milestones and Priorities to Further Advance Its Therapeutics Portfolio for Neurodegeneration and Lysosomal Storage Diseases
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Third Quarter 2023 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports Second Quarter 2023 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Robust Reduction in Neurofilament Light (NfL) with DNL310 (ETV:IDS) Treatment in MPS II (Hunter Syndrome)
Other events · EX-99.1 to Form 8-K
Denali Therapeutics Reports First Quarter 2023 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Key Anticipated 2023 Milestones for Its Therapeutic Portfolio for Neurodegeneration and Lysosomal Storage Diseases
Regulation FD disclosure · EX-99.1 to Form 8-K
Denali Therapeutics Reports Third Quarter 2022 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Pricing of $275 Million Public Offering of Common Stock
Material agreement · Other events · EX-99.1 to Form 8-K
Denali Therapeutics Announces Proposed Offering of Common Stock
Results of operations · Other events · EX-99.1 to Form 8-K
EX-99.2 to Form 8-K
Results of operations · Other events · EX-99.2 to Form 8-K
Risks Related to Our Business, Financial Condition and Capital Requirements
Results of operations · Other events · EX-99.3 to Form 8-K
Denali Therapeutics Reports Second Quarter 2022 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports First Quarter 2022 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Reports Fourth Quarter and Full Year 2021 Financial Results and Business Highlights
Results of operations · EX-99.1 to Form 8-K
Denali Therapeutics Announces Progression and Expansion of Broad Therapeutic Portfolio for Neurodegeneration and Expected Key Milestones in 2022
Regulation FD disclosure · EX-99.1 to Form 8-K