COCPNasdaqPharmaceutical PreparationsFiscal year ends December 31
Cocrystal Pharma, Inc.
Financials through Q2 FY2026, quarter ended Jun 30, 2026Last filing: 10-Q on Aug 13, 2026
$0.95−0.07 (-7.20%)
Close on Oct 19, 2026
- Market cap
- $13.05M
- P/E (TTM)
- –
- Dividend yield
- –
Ownership
Institutional holdings as of Jun 30, 2026, from 13F filings
Held by institutions
5.8%
1M of 19M shares
Institutional holders
27
7 new, 6 sold out
Net institutional buying
0M
In Q2 2026
Insider trades, 12 months
11 buys · 0 sales
Net bought $300.53K
Shares held by institutions
Holders of more than 5%
Latest Schedule 13D (active) or 13G (passive) filed by each holder
| Holder | Shares | % of class | Filing | As of |
|---|---|---|---|---|
| Opko Health, Inc. | 5,692,916 | 29.60% | 13D (active) | Jul 31, 2026 |
| Phillip Frost, M.D. | 2,784,719 | 13.90% | 13D (active) amendment | Aug 3, 2026 |
| Sabby Volatility Warrant Master Fund, Ltd. | – | – | 13G (passive) amendment | Dec 31, 2023 |
Top institutional holders
13F holdings as of Jun 30, 2026
| Holder | Shares | % of COCP | Value | Change | % of portfolio |
|---|---|---|---|---|---|
| Vanguard Capital Management LLC | 358,228 | 1.86% | $376.14K | +118,257 | 0.00% |
| Renaissance Technologies LLC | 179,628 | 0.93% | $188.61K | +55,700 | 0.00% |
| Two Sigma Investments, LP | 175,379 | 0.91% | $184.15K | New | 0.00% |
| Geode Capital Management, LLC | 76,208 | 0.40% | $80.03K | −14,023 | 0.00% |
| BlackRock, Inc. | 73,746 | 0.38% | $77.43K | – | 0.00% |
| Citadel Advisors LLC | 45,118 | 0.23% | $47.37K | New | 0.00% |
| Neuberger Berman Group LLC | 31,886 | 0.17% | $33.48K | – | 0.00% |
| XTX Topco Ltd | 29,342 | 0.15% | $30.81K | −6,689 | 0.00% |
| Jane Street Group, LLC | 25,761 | 0.13% | $27.05K | +13,050 | 0.00% |
| Vanguard Fiduciary Trust Co | 24,016 | 0.12% | $25.22K | – | 0.00% |
| State Street Corp | 20,543 | 0.11% | $21.57K | – | 0.00% |
| Hrt Financial LP | 20,336 | 0.11% | $21 | New | 0.00% |
| Parallel Advisors, LLC | 12,569 | 0.07% | $13.20K | – | 0.00% |
| Northern Trust Corp | 11,921 | 0.06% | $12.52K | – | 0.00% |
| Ground Swell Capital, LLC | 10,752 | 0.06% | $11.29K | New | 0.01% |
| Wells Fargo & Company/Mn | 6,257 | 0.03% | $6.57K | −782 | 0.00% |
| UBS Group AG | 4,133 | 0.02% | $4.34K | −511 | 0.00% |
| Tower Research Capital LLC (TRC) | 3,984 | 0.02% | $4.18K | −264 | 0.00% |
| Morgan Stanley | 871 | 0.00% | $915 | −77 | 0.00% |
| Northwestern Mutual Wealth Management Co | 817 | 0.00% | $858 | – | 0.00% |
Institutional buying and selling by quarter
Positions opened, added to, reduced and closed by 13F filers
| Quarter | Holders | Shares held | % of shares | New / added | Reduced / closed | Shares bought | Shares sold |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 27 | 1M | 5.8% | 7 / 3 | 7 / 6 | 0M | 0M |
| Q1 2026 | 26 | 1M | 4.0% | 4 / 6 | 4 / 4 | 0M | 0M |
| Q4 2025 | 28 | 1M | 4.0% | 7 / 3 | 9 / 1 | 0M | 0M |
| Q3 2025 | 22 | 1M | 3.5% | 4 / 3 | 5 / 4 | 0M | 0M |
| Q2 2025 | 22 | 1M | 3.6% | 1 / 6 | 4 / 3 | 0M | 0M |
| Q1 2025 | 24 | 1M | 3.9% | 2 / 5 | 5 / 2 | 0M | 0M |
| Q4 2024 | 24 | 1M | 3.7% | 5 / 4 | 5 / 1 | 0M | 0M |
| Q3 2024 | 20 | 1M | 3.7% | 7 / 4 | 2 / 0 | 0M | 0M |
| Q2 2024 | 14 | 1M | 3.5% | 1 / 3 | 6 / 3 | 0M | 0M |
| Q1 2024 | 16 | 1M | 4.4% | 0 / 8 | 3 / 1 | 0M | 0M |
| Q4 2023 | 17 | 1M | 3.9% | 2 / 4 | 4 / 1 | 0M | 0M |
| Q3 2023 | 16 | 1M | 3.7% | 0 / 6 | 3 / 4 | 0M | 0M |
Top mutual fund and ETF holders
Latest monthly portfolio reports (Form N-PORT)
| Fund | Shares | % of COCP | Value | % of fund | As of |
|---|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 187,266 | 0.97% | $196.63K | 0.00% | Jun 30, 2026 |
| Vanguard Extended Market Index Fund | 170,962 | 0.89% | $179.51K | 0.00% | Jun 30, 2026 |
| Fidelity Extended Market Index Fund | 49,807 | 0.26% | $55.78K | 0.00% | May 31, 2026 |
| Fidelity Series Total Market Index Fund | 9,629 | 0.05% | $10.78K | 0.00% | May 31, 2026 |
| Fidelity Total Market Index Fund | 8,526 | 0.04% | $9.55K | 0.00% | May 31, 2026 |
| Fidelity Nasdaq Composite Index Fund | 6,122 | 0.03% | $6.86K | 0.00% | May 31, 2026 |
Officers, directors and major owners
People who filed Forms 3, 4 or 5 in the last two years
| Name | Role | Shares owned | % of shares | Latest filing |
|---|---|---|---|---|
| James Sapirstein | Chief Executive Officer | – | – | Jun 3, 2026 |
| James Joseph Martin | Co-CEO and CFO | 44,167 | 0.23% | Jan 13, 2026 |
| Sam Lee | President and Co-CEO | 76,355 | 0.40% | Jan 13, 2026 |
| Carol L. Brosgart | Director | – | – | Aug 21, 2026 |
| Phillip Md Et Al Frost | Director, 10% owner | 2,020,651 | 10.49% | Aug 6, 2026 |
| Anthony J. Japour | Director | 14,924 | 0.08% | Jan 13, 2026 |
| Fred Hassan | Director | 1,383,009 | 7.18% | Jan 13, 2026 |
| Richard C. Pfenniger Jr | Director | 31,400 | 0.16% | Jan 13, 2026 |
| Roger D. Kornberg | Director | 67,878 | 0.35% | Jan 13, 2026 |
| Steven D. Rubin | Director | 7,206,235 | 37.41% | Jan 13, 2026 |
Insider trades
Common stock transactions reported on Form 4, newest first
| Insider | Date | Transaction | Shares | Price | Value | Shares after |
|---|---|---|---|---|---|---|
| Phillip Md Et Al Frost Director, 10% owner | Aug 5, 2026 | Buy | +10,000 | $0.98 | $9.80K | 1,993,551 |
| Phillip Md Et Al Frost Director, 10% owner | Aug 3, 2026 | Buy | +75,000 | $0.94 | $70.50K | 1,983,551 |
| Phillip Md Et Al Frost Director, 10% owner | Feb 24, 2026 | Buy | +20,000 | $1.00 | $20.00K | 1,908,551 |
| Phillip Md Et Al Frost Director, 10% owner | Feb 6, 2026 | Buy | +50,000 | $0.95 | $47.50K | 1,888,551 |
| Phillip Md Et Al Frost Director, 10% owner | Dec 31, 2025 | Buy | +50,000 | $0.95 | $47.50K | 1,838,551 |
| Phillip Md Et Al Frost Director, 10% owner | Dec 30, 2025 | Buy | +20,000 | $0.97 | $19.40K | 1,788,551 |
| Phillip Md Et Al Frost Director, 10% owner | Dec 26, 2025 | Buy | +40,000 | $0.97 | $38.80K | 1,768,551 |
| Phillip Md Et Al Frost Director, 10% owner | Dec 24, 2025 | Buy | +25,000 | $0.97 | $24.25K | 1,728,551 |
| Phillip Md Et Al Frost Director, 10% owner | Nov 26, 2025 | Buy | +1,500 | $1.00 | $1.50K | 1,701,051 |
| Phillip Md Et Al Frost Director, 10% owner | Nov 26, 2025 | Buy | +2,500 | $0.99 | $2.48K | 1,703,551 |
| Phillip Md Et Al Frost Director, 10% owner | Nov 25, 2025 | Buy | +20,000 | $0.94 | $18.80K | 1,699,551 |
| Phillip Md Et Al Frost Director, 10% owner | Oct 28, 2025 | Award | +359,713 | $1.39 | $500.00K | 1,679,551 |
| Richard C. Pfenniger Jr Director | Oct 28, 2025 | Award | +20,000 | – | – | 31,400 |
| Fred Hassan Director | Oct 28, 2025 | Award | +359,713 | $1.39 | $500.00K | 1,383,009 |
| James Joseph Martin Co-CEO and CFO | Oct 28, 2025 | Award | +3,598 | $1.39 | $5.00K | 44,167 |
| Sam Lee President and Co-CEO | Oct 9, 2024 | Award | +40,000 | – | – | 76,355 |
| James Joseph Martin Co-CEO and CFO | Oct 9, 2024 | Award | +40,000 | – | – | 40,569 |
| Fred Hassan Director | Oct 9, 2024 | Award | +8,067 | – | – | 1,023,296 |
| Steven D. Rubin Director | Oct 9, 2024 | Award | +18,957 | – | – | 2,660,242 |
| Phillip Md Et Al Frost Director, 10% owner | Oct 9, 2024 | Award | +27,100 | – | – | 27,100 |
| Roger D. Kornberg Director | Oct 9, 2024 | Award | +28,109 | – | – | 28,109 |
| Anthony J. Japour Director | Oct 9, 2024 | Award | +14,924 | – | – | 14,924 |
| Richard C. Pfenniger Jr Director | Oct 9, 2024 | Award | +8,067 | – | – | 11,400 |
| Phillip Md Et Al Frost Director, 10% owner | Apr 4, 2023 | Buy | +1,015,229 | $1.97 | $2.00M | 1,319,838 |
| Richard C. Pfenniger Jr Director | Aug 20, 2021 | Buy | +40,000 | $1.03 | $41.20K | 40,000 |
| Raymond F. Schinazi 10% owner | May 4, 2021 | Sale | −575,000 | $2.95 | $1.70M | 7,674,960 |
| Raymond F. Schinazi 10% owner | Oct 25, 2019 | Buy | +7,906 | $1.15 | $9.09K | 9,257,863 |
| Raymond F. Schinazi 10% owner | Oct 24, 2019 | Buy | +5,094 | $1.15 | $5.86K | 9,249,957 |
| Raymond F. Schinazi 10% owner | Oct 23, 2019 | Buy | +3,935 | $1.04 | $4.09K | 9,244,863 |
| Raymond F. Schinazi Director, 10% owner | May 10, 2018 | Option exercise | +263,158 | $1.90 | $500.00K | 985,384 |
| Raymond F. Schinazi Director, 10% owner | May 10, 2018 | Award | +10,209 | $1.90 | $19.40K | 995,593 |
| Raymond F. Schinazi Director, 10% owner | May 3, 2018 | Award | +420,737 | $1.90 | $799.40K | 722,226 |
| Phillip Md Et Al Frost Director, 10% owner | May 3, 2018 | Award | +105,263 | $1.90 | $200.00K | 3,655,265 |
| Raymond F. Schinazi Director, 10% owner | Jul 11, 2017 | Option exercise | +1,706,978 | $0.05 | $85.35K | 277,227,831 |
| Raymond F. Schinazi Director, 10% owner | Apr 20, 2017 | Award | +4,166,667 | $0.24 | $1.00M | 9,044,717 |
| Sam Lee PRESIDENT | Dec 23, 2016 | Sale | −2,200,000 | $0.44 | $968.00K | 13,087,847 |
| Gary Wilcox INTERIM CEO, Director | Sep 1, 2016 | Buy | +10,000 | $0.41 | $4.10K | 16,948,605 |
| Raymond F. Schinazi Director, 10% owner | Sep 1, 2016 | Buy | +4,878,050 | $0.41 | $2.00M | 4,878,050 |
| David S. Block Director | Sep 1, 2016 | Buy | +10,000 | $0.41 | $4.10K | 168,696 |
| Steven D. Rubin Director | Mar 15, 2016 | Buy | +39,216 | $0.51 | $20.00K | 733,484 |
| David S. Block Director | Mar 15, 2016 | Buy | +50,000 | $0.51 | $25.50K | 158,696 |
| Jane Ph D. Hsiao Director | Mar 15, 2016 | Buy | +1,235,294 | $0.51 | $630.00K | 3,435,294 |
| Phillip Md Et Al Frost Director, 10% owner | Mar 15, 2016 | Buy | +2,941,177 | $0.51 | $1.50M | 106,500,147 |
| Jeffrey A. Meckler CHIEF EXECUTIVE OFFICER, Director | Mar 15, 2016 | Buy | +294,118 | $0.51 | $150.00K | 657,161 |
| Steven D. Rubin Director | Mar 15, 2016 | Buy | +39,216 | $0.51 | $20.00K | 93,564 |
| Raymond F. Schinazi Director, 10% owner | Mar 15, 2016 | Buy | +2,941,176 | $0.51 | $1.50M | 275,520,853 |
| Gary Wilcox Director | Mar 15, 2016 | Buy | +49,020 | $0.51 | $25.00K | 16,938,605 |
| Jeffrey A. Meckler CHIEF EXECUTIVE OFFICER, Director | Dec 23, 2015 | Buy | +100,000 | $0.58 | $58.00K | 363,043 |
| Raymond F. Schinazi Director, 10% owner | Apr 21, 2015 | Buy | +3,464,855 | $0.92 | $3.19M | 272,579,677 |
| Jeffrey A. Meckler Director | Mar 25, 2015 | Buy | +163,043 | $0.92 | $150.00K | 263,043 |
| Steven D. Rubin Director | Mar 25, 2015 | Buy | +54,348 | $0.92 | $50.00K | 694,268 |
| David S. Block Director | Mar 25, 2015 | Buy | +108,696 | $0.92 | $100.00K | 108,696 |
| Gamma Investments Trust Frost 10% owner | Mar 25, 2015 | Buy | +3,464,855 | $0.92 | $3.19M | 103,558,969 |
| Jane Ph D. Hsiao Director | Mar 25, 2015 | Buy | +2,200,000 | $0.92 | $2.02M | 2,200,000 |
| Gary Wilcox CHIEF EXECUTIVE OFFICER, Director | Mar 25, 2015 | Buy | +54,348 | $0.92 | $50.00K | 16,889,585 |
| Phillip Md Et Al Frost Director, 10% owner | Mar 3, 2015 | Option exercise | +87,726,389 | – | – | 100,094,114 |
| Jane Ph D. Hsiao Director | Mar 3, 2015 | Option exercise | +5,496,654 | – | – | 5,496,654 |
| Raymond F. Schinazi Director, 10% owner | Mar 3, 2015 | Option exercise | +269,114,822 | – | – | 269,114,822 |
| Sam Lee PRESIDENT | Mar 3, 2015 | Option exercise | +15,287,847 | – | – | 15,287,847 |
| Gary Wilcox CHIEF EXECUTIVE OFFICER, Director | Mar 3, 2015 | Option exercise | +16,835,237 | – | – | 16,835,237 |
Awards, option exercises, tax withholding and gifts are shown alongside open-market buys and sales. Each name links to the filing on SEC EDGAR.